O⁶-Methylgaunine-DNA Methyltransferase Activity in Cerebral Gliomas: A guidance for nitrosourea treatment?

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Randomized Comparisons of Radiotherapy and Nitrosoureas for the Treatment of Malignant Glioma after Surgery

1980 • 1,625 citations

Meta-analysis of radiation therapy with and without adjuvant chemotherapy for malignant gliomas in adults

1993 • 872 citations

Results of a randomized trial comparing BCNU plus radiotherapy, streptozotocin plus radiotherapy, BCNU plus hyperfractionated radiotherapy, and BCNU following misonidazole plus radiotherapy in the postoperative treatment of malignant glioma

1989 • 178 citations

O⁶-Alkylguanine-DNA alkyltransferase activity in human brain and brain tumors

1984 • 137 citations

O6-Alkylguanine-DNA alkyltransferase and sensitivity to procarbazine in human brain-tumor xenografts

1989 • 122 citations

Response of cultured human brain tumors to nitrosoureas: Correlation with clinical data

1981 • 66 citations

O6-methylguanine methyltransferase activity and sensitivity of Japanese tumor cell strains to 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)- 3-nitrosourea hydrochloride.

1987 • 32 citations

Hypersensitivity of human tumor xenografts lacking O⁶-alkylguanine-DNA alkyltransferase to the anti-tumor agent 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea

1989 • 25 citations

Tumor Cell Resistance

2015 • 25 citations

Linkage between O6-methylguanine-DNA methyltransferase (O6-MT) activity and cellular resistance to antitumour nitrosoureas in cultured rat brain tumour cell strains

1990 • 17 citations

O6-Methylguanine-DNA Methyltransferase (O6-MT) Activity as an Index of Drug Responsiveness to Antitumor Chloroethylnitrosoureas in Xenografted Brain Tumors

1991 • 7 citations

DNA lability induced by nimustine and ramustine in rat glioma cells.

1988 • 7 citations