The mode of coupling of adenylate cyclase to hormone receptors and its modulation by GTP

The Glucagon-sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver

1971 • 811 citations

ADENYL CYCLASE AS AN ADRENERGIC RECEPTOR*

1967 • 682 citations

Catecholamine-stimulated GTPase activity in turkey erythrocyte membranes

1976 • 623 citations

Adenyl Cyclase

1962 • 555 citations

Relationship between the beta-adrenergic receptor and adenylate cyclase.

1977 • 497 citations

GTP-binding proteins in membranes and the control of adenylate cyclase activity.

1977 • 456 citations

Adenyl Cyclase in Fat Cells

1969 • 352 citations

Activation of pigeon erythrocyte membrane adenylate cyclase by guanylnucleotide analogues and separation of a nucleotide binding protein.

1975 • 337 citations

Cholera

1973 • 294 citations

The mobile receptor hypothesis and “cooperativity” of hormone binding. Application to insulin

1976 • 258 citations

Evidence for Interdependent Action of Glucagon and Nucleotides on the Hepatic Adenylate Cyclase System

1974 • 244 citations

Adenyl Cyclase in Fat Cells

1970 • 235 citations

A persistent active state of the adenylate cyclase system produced by the combined actions of isoproterenol and guanylyl imidodiphosphate in frog erythrocyte membranes.

1975 • 221 citations

Stimulatory and Inhibitory Effects of Guanyl Nucleotides on Fat Cell Adenylate Cyclase

1973 • 198 citations

Coupling of hormone receptors to adenylate cyclase of different cells by cell fusion

1977 • 119 citations

Activation of Turkey erythrocyte adenylate cyclase and blocking of the catecholamine-stimulated GTPase by guanosine 5′-(γ-thio) triphosphate

1977 • 106 citations

Synergistic activation of adenylate cyclase by guanylyl imidophosphate and epinephrine

1976 • 91 citations

The quantitative aspects of drug-receptor interactions.

1975 • 83 citations

THE ROLE OF ADENINE AND GUANINE NUCLEOTIDES IN THE ACTIVITY AND RESPONSE OF ADENYLATE CYCLASE SYSTEMS TO HORMONES: EVIDENCE FOR MULTI-SITE TRANSITION STATES

1974 • 77 citations

Ligand specificity and characteristics of the β-adrenergic receptor in turkey erythrocyte plasma membranes

1975 • 59 citations

The role of GTP in the activation of adenylate cyclase

1977 • 54 citations

The absence of desensitization in the beta adrenergic receptors of turkey reticulocytes and erythrocytes and its possible origin

1978 • 46 citations

The activation of adenylate cyclase by 1‐epinephrine and guanylylimidodiphosphate and its reversal by 1‐epinephrine and GTP

1977 • 42 citations

Direct Determination of Ligand Interactions with Beta-Adrenergic Receptors on Intact Turkey Erythrocytes: Correlation of Binding with Biological Activity*

1976 • 33 citations

The regulatory control of β-receptor dependent adenylate cyclase

1976 • 30 citations

An irreversible blocker for the β-adrenergic receptor

1976 • 29 citations

Activation of turkey erythrocyte adenylate cyclase by two receptors: Adenosine and catecholamines

1977 • 27 citations

Simultaneous visualization of noradrenergic fibres and β-adrenoreceptors in pre- and postsynaptic regions in rat brain

1977 • 14 citations