Nigral D1 and striatal D2 receptors mediate the behavioral effects of dopamine agonists

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

The rat brain in stereotaxic coordinates

1983 • 28,962 citations

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1962 • 27,228 citations

Statistical Principles in Experimental Design

1964 • 8,376 citations

Stereotaxic Mapping of the Monoamine Pathways in the Rat Brain*

1971 • 3,816 citations

Multiple receptors for dopamine

1979 • 3,739 citations

Postsynaptic Supersensitivity after 6‐Hydroxy‐dopamine Induced Degeneration of the Nigro‐striatal Dopamine System

1971 • 1,922 citations

Quantitative autoradiographic localization of the D1 and D2 subtypes of dopamine receptors in rat brain

1986 • 742 citations

Dendritic release of dopamine in the substantia nigra

1981 • 732 citations

Release of dopamine from dendrites in rat substantia nigra

1976 • 644 citations

Two Distinct Central Serotonin Receptors with Different Physiological Functions

1981 • 640 citations

Dopamine in dendrites of substantia nigra neurons: suggestions for a role in dendritic terminals

1975 • 482 citations

D ₁ Dopamine Receptor Activation Required for Postsynaptic Expression of D ₂ Agonist Effects

1987 • 468 citations

Direct chemical stimulation of dopaminergic mechanisms in the neostriatum of the rat

1969 • 331 citations

Site of action of dopamine and apomorphine on compulsive gnawing behaviour in rats

1966 • 330 citations

Release of dopamine in vivo from cat substantia nigra

1977 • 318 citations

Autoradiographic localization of D1 dopamine receptors in the rat brain with [3H]SCH 23390

1986 • 310 citations

Somatosensory inattention after dopamine-depleting intracerebral 6-OHDA injections: Spontaneous recovery and pharmacological control

1979 • 279 citations

Afferent and Efferent Relationships of the Basal Ganglia

1984 • 270 citations

Dopamine release in substantia nigra?

1976 • 249 citations

Dopamine-Sensitive Adenylate Cyclase: Location in Substantia Nigra

1977 • 227 citations

Supersensitivity to apomorphine following destruction of the ascending dopamine neurons: Quantification using the rotational model

1977 • 201 citations

Dopaminergic mechanisms and motor function: Characterization of D-1 and D-2 dopamine receptor interactions

1986 • 198 citations

Lisuride and Other Dopamine Agonists

1983 • 198 citations

Behavioral correlations of dopamine receptor activation

1983 • 188 citations

CNS Dopamine Autoreceptors: Distribution, Pharmacology, and Function^a

1984 • 185 citations

Effects of the putative D-1 antagonist SCH 23390 on stereotyped behaviour induced by the D-2 agonist RU24213

1985 • 179 citations

Sniffing, rearing and locomotor responses to the D-1 dopamine agonist R-SK&F 38393 and to apomorphine: Differential interactions with the selective D-1 and D-2 antagonists SCH 23390 and metoclopramide

1985 • 158 citations

Selective D1 and D2 dopamine agonists differentially alter basal ganglia glucose utilization in rats with unilateral 6-hydroxydopamine substantia nigra lesions

1987 • 156 citations

Differential inhibition by dopamine D-1 and D-2 antagonists of circling behaviour induced by dopamine agonists in rats with unilateral 6-hydroxydopamine lesions

1984 • 153 citations

Differential involvement of dopamine D-1 and D-2 receptors in the circling behaviour induced by apomorphine, SK & F 38393, pergolide and LY 171555 in 6-hydroxydopamine-lesioned rats

1985 • 152 citations

D-1 dopamine receptors in the rat brain: Autoradiographic localization using [3H]SCH 23390

1985 • 148 citations

Direct dopaminergic action of lisuride hydrogen maleate, an ergot derivative, in mice

1976 • 144 citations

Effects of locally applied D-1 and D-2 receptor agonists and antagonists studied with brain dialysis

1988 • 136 citations

D-1 dopamine receptor stimulation enables the inhibition of nucleus accumbens neurons by a D-2 receptor agonist

1987 • 134 citations

Effect of lisuride and other ergot derivatives on monoaminergic mechanisms in rat brain

1977 • 127 citations

Topography of substantia nigra innervation by D1 receptor-containing striatal neurons

1987 • 124 citations

Bromocriptine induces marked locomotor stimulation in dopamine-depleted mice when D-1 dopamine receptors are stimulated with SKF38393

1986 • 121 citations

Effects of lisuride and LSD on cerebral monoamine systems and hallucinosis

1978 • 120 citations

Differences in the nature of the stereotyped behaviour induced by aporphine derivatives in the rat and in their actions in extrapyramidal and mesolimbic brain areas

1975 • 108 citations

D1 and D2 dopamine agonist synergism: separate sites of action?

1987 • 95 citations

Selective and stereospecific interactions of R-SK&F 38393 with [3H]piflutixol but not [3H]spiperone binding to striatal D1 and D2 dopamine receptors: Comparisons with SCH 23390

1984 • 92 citations

Opposing Roles of Dopamine D₁ and D₂ Receptors in Nigral γ‐[³H]Aminobutyric Acid Release?

1987 • 91 citations

Plasticity of [14C]2-deoxy-d-glucose incorporation into neostriatum and related structures in response to dopamine neuron damage and apomorphine replacement

1980 • 89 citations

Functions of the basal ganglia

1985 • 83 citations

The effects ofl-DOPA on regional cerebral glucose utilization in rats with unilateral lesions of the substantia nigra

1986 • 78 citations

Different neuronal location of [3H]SCH 23390 binding sites in pars reticulata and pars compacta of the substantia nigra in the rat

1986 • 75 citations

Effects of dopaminergic stimulation on functional brain metabolism in rats with unilateral substantia nigra lesions

1983 • 69 citations

Computer imaging and analysis of dopamine (D2) and serotonin (S2) binding sites in rat basal ganglia or neocortex labeled by [3H]spiroperidol.

1985 • 68 citations

Evidence that the substantia nigra is a site of action for l-DOPA

1988 • 66 citations

Topography of dopamine behaviours mediated by D1 and D2 receptors revealed by intrastriatal injection of SKF 38393, lisuride and apomorphine in rats with a unilateral 6-hydroxydopamine-induced lesion

1987 • 50 citations

Behavioural effects and supersensitivity following nigral dopamine receptor stimulation

1980 • 50 citations

Rotation produced by administration of dopamine and related substances directly into the supersensitive caudate nucleus

1978 • 43 citations

Rotational behaviour elicited by intracerebral injections of apomorphine and pergolide in 6‐hydroxy‐dopamine‐lesioned rats. I: Comparison between systemic and intrastriatal injections

1985 • 38 citations

Nigral dopaminergic mechanisms in drug-induced circling

1983 • 36 citations

Acute reduction of dopamine levels alters responses of basal ganglia neurons to selective D-1 and D-2 dopamine receptor stimulation

1988 • 30 citations

Multifocal brain sites for apomorphine-induced circling and other stereotyped motor behaviour in the 6-hydroxydopamine-lesioned rat

1982 • 29 citations

Behavioural evidence for the functionality of D-2 but not D-1 dopamine receptors at multiple brain sites in the 6-hydroxydopamine-lesioned rat

1987 • 28 citations

Role of the substantia nigra in the expression of dopamine D1 receptor-mediated and D2 receptor-mediated behaviours

1987 • 21 citations

Rotation following intranigral injections of a selective D1 or a selective D2 dopamine receptor agonist in rats

1988 • 19 citations

Behavioural effects in the rat after acute unilateral intranigral infusions of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1985 • 8 citations