The Sympathetic Nervous System in Hypertension

Sodium ions, calcium ions, blood pressure regulation, and hypertension: a reassessment and a hypothesis

1977 • 1,317 citations

Electrogenic sodium pump in nerve and muscle cells.

1972 • 787 citations

Age as a determinant of renal sodium conservation in normal man.

1976 • 420 citations

Factors influencing blood pressure in salt-sensitive patients with hypertension

1980 • 370 citations

Decreased Beta-adrenoreceptor responsiveness as related to age, blood pressure, and plasma catecholamines in patients with essential hypertension.

1980 • 325 citations

The role of the solitary and paramedian reticular nuclei in mediating cardiovascular reflex responses from carotid baro‐ and chemoreceptors

1972 • 257 citations

Effect of chronic hypertension and sympathetic denervation on wall/lumen ratio of cerebral vessels.

1980 • 253 citations

Receptors under pressure. An update on baroreceptors.

1980 • 250 citations

Role of the Renal Sympathetic Nerves in the Development and Maintenance of Hypertension in the Spontaneously Hypertensive Rat

1980 • 217 citations

Central and peripheral adrenergic mechanisms in the development of deoxycorticosterone-saline hypertension in rats.

1975 • 201 citations

Role of paraventricular and supraoptic nuclei in central cardiovascular regulation in the cat

1980 • 186 citations

Role of Central and Peripheral Adrenergic Mechanisms in Neurogenic Hypertension Produced by Brainstem Lesions in Rat

1974 • 163 citations

Reduced baroreceptor sensitivity in borderline hypertension.

1975 • 160 citations

Effects of high and low sodium intake on arterial pressure and forearm vasular resistance in borderline hypertension. A preliminary report.

1975 • 156 citations

Disturbances in neurogenic control of the circulation

1981 • 155 citations

Depressed function of a ouabain-sensitive sodium-potassium pump in blood vessels from renal hypertensive dogs.

1976 • 153 citations

Abnormal baroreflex control of heart rate in prehypertensive and hypertensive Dahl genetically salt-sensitive rats.

1981 • 140 citations

Prevention of the development of renal hypertension by anteroventral third ventricular tissue lesions.

1977 • 137 citations

Comparison of Sympathetic Nerve Activity in Normotensive and Hypertensive Subjects

1973 • 133 citations

Electrogenic sodium pump in arterial smooth muscle cells

1974 • 130 citations

Experimental hypertension of the rat: Reciprocal changes of norepinephrine turnover in heart and brain-stem

1971 • 128 citations

Relationship between Sodium Intake and Norepinephrine Storage during the Development of Experimental Hypertension

1968 • 126 citations

Effects of central and peripheral angiotensin blockade in hypertensive rats

1978 • 117 citations

Humoral factors and the sodium-potassium pump in volume expanded hypertension

1979 • 115 citations

Neural Mechanisms in Hypertension

1980 • 109 citations

Enhanced alpha-adrenoreceptor-mediated vasoconstriction in essential hypertension.

1981 • 106 citations

Neurogenic contribution to hindquarters vasoconstriction during high sodium intake in Dahl strain of genetically hypertensive rat

1980 • 105 citations

Attenuated pressor responses to intracranially injected stimuli and altered antidiuretic activity following preoptic-hypothalamic periventricular ablation

1978 • 103 citations

Prevention of salt-induced hypertension in the Dahl strain by 6-hydroxydopamine

1979 • 102 citations

Augmentation of cardiopulmonary baroreflex control of forearm vascular resistance in borderline hypertension.

1982 • 102 citations

Differential baroreflex control of heart rate and vascular resistance in rabbits. Relative role of carotid, aortic, and cardiopulmonary baroreceptors.

1982 • 99 citations

Role of the renal nerves in the pathogenesis of one-kidney renal hypertension in the rat.

1981 • 97 citations

Altered calcium sequestration by subcellular fractions of vascular smooth muscle from spontaneously hypertensive rats

1976 • 95 citations

Interrelationships of sodium intake, hypertension, and norepinephrine storage in the rat.

1969 • 94 citations

Decreased cardiac beta-adrenergic receptors in deoxycorticosterone-salt and renal hypertensive rats.

1979 • 93 citations

Calcium accumulation and enzymatic activities of subcellular fractions from aortas and ventricles of genetically hypertensive rats.

1976 • 90 citations

Central resetting of baroreflex in the spontaneously hypertensive rat.

1983 • 89 citations

Control of blood pressure by carotid sinus baroreceptors in human beings

1979 • 82 citations

Renal vascular reactivity in the young spontaneously hypertensive rat.

1980 • 81 citations

The effect of ouabain on noradrenaline output from peripheral adrenergic neurones of isolated guinea‐pig vas deferens

1978 • 68 citations

Effects of sodium, angiotensin, and steroids on vascular reactivity in man.

1974 • 67 citations

Sympathetic nerves protect against stroke in stroke-prone hypertensive rats. A preliminary report.

1981 • 67 citations

Cellular basis for increased sensitivity of vascular smooth muscle in spontaneously hypertensive rats.

1976 • 63 citations

Alterations in central and peripheral adrenergic receptors in deoxycorticosterone/salt hypertensive rats

1980 • 56 citations

Arterial baroreflexes in renal hypertensive rabbits. Selectivity and redundancy of baroreceptor influence on heart rate, vascular resistance, and lumbar sympathetic nerve activity.

1983 • 54 citations

Effect of lesions of the anteroventral third ventricle (AV3V) on the development of hypertension in spontaneously hypertensive rats.

1982 • 50 citations

Adrenergic reactivity of the myocardium in hypertension

1978 • 49 citations

Comparison of β-adrenergic receptors and the adenylate cyclase system with muscarinic receptors and guanylate cyclase activities in the heart of spontaneously hypertensive rats

1981 • 47 citations

Sympathetic cross-innervation of SHR and genetic controls suggests a trophic influence on vascular muscle membranes.

1981 • 42 citations

Effect of chronic sodium depletion on cerebrospinal fluid and plasma catecholamines.

1981 • 39 citations

Sensitization of vagal cardiopulmonary baroreflex by chronic digoxin

1982 • 37 citations

Relationship between plasma sodium concentration and vascular reactivity in man

1971 • 37 citations

Peripheral ß-Receptor Responsiveness in Patients With Essential Hypertension

1979 • 31 citations

Effect of cross-transplantation on normotensive and spontaneously hypertensive rat arterial muscle membrane.

1981 • 22 citations

Possible role of phosphorylation-dephosphorylation in the regulation of calcium metabolism in cardiovascular tissues of SHR.

1980 • 12 citations

Autonomic dysfunctions in human hypertension.

1981 • 11 citations

Reduced Responsiveness to -Adrenergic Stimulation in Renal Hypertensive Rats

1978 • 8 citations