Anticonvulsant and proconvulsant effects of inhibitors of GABA degradation in the amygdala-kindling model

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Modification of seizure activity by electrical stimulation: II. Motor seizure

1972 • 6,939 citations

A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples

1978 • 6,494 citations

Stereotaxic atlases for the cat, rabbit and rat

1967 • 508 citations

Enzyme-Activated Irreversible Inhibitors

1979 • 420 citations

Evidence implicating substantia nigra in regulation of kindled seizure threshold

1984 • 301 citations

Electrophysiological methods in biological research

1968 • 278 citations

The Limbic System: Functional Organization and Clinical Disorders

1987 • 256 citations

Seizure Protection and Increased Nerve-Terminal GABA: Delayed Effects of GABA Transaminase Inhibition

1980 • 175 citations

Is amygdala kindling in rats a model for drug-resistant partial epilepsy?

1986 • 163 citations

Dynamic utilization of GABA in substantia nigra: regulation by dopamine and GABA in the striatum, and its clinical and behavioral implications

1981 • 154 citations

GABA in plasma and cerebrospinal fluid of different species. Effects of ?-acetylenic GABA, ?-vinyl GABA and sodium valproate

1979 • 131 citations

The pharmacology of GABA-transaminase inhibitors

1981 • 116 citations

Effect of Inhibitors of GABA Aminotransferase on the Metabolism of GABA in Brain Tissue and Synaptosomal Fractions

1981 • 98 citations

Further evidence for abnormal GABAergic circuits in amygdala-kindled rats

1987 • 97 citations

Anti-seizure and anti-epileptogenic effect of γ-vinyl γ-aminobutyric acid in amygdaloid kindling

1986 • 87 citations

Effects of single doses of vigabatrin on CSF concentrations of GABA, homocarnosine, homovanillic acid and 5-hydroxyindoleacetic acid in patients with complex partial epilepsy

1988 • 78 citations

Effects of γ-acetylenic GABA and γ-vinyl GABA on metrazol-activated, and kindled seizures

1979 • 69 citations

In vivo effects of aminooxyacetic acid and valproic acid on nerve terminal (synaptosomal) GABA levels in discrete brain areas of the rat

1985 • 66 citations

Effect of microinjections of γ-vinyl GABA or isoniazid into substantia nigra on the development of amygdala kindling in rats

1987 • 65 citations

Anticonvulsant efficacy of clonazepam and the β-carboline ZK 93423 during chronic treatment in amygdala-kindled rats

1987 • 64 citations

Improved Method for Isolating Synaptosomes from 11 Regions of One Rat Brain: Electron Microscopic and Biochemical Characterization and Use in the Study of Drug Effects on Nerve Terminal γ‐Aminobutyric Acid in Vivo

1985 • 61 citations

Amygdaloid Kindling and the GABA System

1980 • 61 citations

Development of tolerance to the anticonvulsant effect of diazepam in amygdala-kindled rats

1985 • 58 citations

Epileptogenic γ-aminobutyric acid-withdrawal syndrome after chronic, intracortical infusion in baboons

1987 • 52 citations

Gamma-vinyl GABA

1985 • 52 citations

Anticonvulsant and biochemical effects of inhibitors of gaba aminotransferase and valproic acid during subchronic treatment in mice

1982 • 49 citations

Pharmacological investigation of gamma-aminobutyric acid (gaba) and fully-developed generalized seizures in the amygdala-kindled rat

1982 • 49 citations

Kindling-induced changes in EEG recorded during stimulation from the site of stimulation

1987 • 44 citations

Comparison of the anticonvulsant effects of two novel GABA uptake inhibitors and diazepam in amygdaloid kindled rats

1985 • 43 citations

Development of a synaptosomal model to determine drug-induced in vivo changes in GABA-levels of nerve endings in 11 brain regions of the rat

1984 • 43 citations

Microinjections of the γ-aminobutyrate antagonist, bicuculline methiodide, into the caudate-putamen prevent amygdala-kindled seizures in rats

1987 • 41 citations

One to three day dose intervals during subchronic treatment of epileptic gerbils with γ-vinyl GABA: anticonvulsant efficacy and alterations in regional brain GABA levels

1987 • 40 citations

Tolerance to Beneficial and Adverse Effects of Antiepileptic Drugs

1987 • 36 citations

Anticonvulsant effect of intracortical, chronic infusion of GABA in kindled rats: Focal seizures upon withdrawal

1987 • 36 citations

Marked increase in anticonvulsant activity but decrease in wet-dog shake behaviour during short-term treatment of amygdala-kindled rats with valproic acid

1988 • 34 citations

Inhibition of kindling-induced generalized seizures by aminooxyacetic acid

1980 • 31 citations

Development of tolerance to the anticonvulsant effect of GABAmimetic drugs in genetically epilepsy-prone gerbils

1986 • 27 citations

Epilepsy and GABA Receptor Agonists Basic and Therapeutic Research

1986 • 19 citations

γ-Acetylenic GABA antagonizes the decrease in synaptosomal GABA concentrations but not the Scizures induced by 3-mercaptopropionic acid in rats

1986 • 9 citations