Annexin 1 is Overexpressed and Specifically Secreted During Experimentally Induced Colitis in Rats

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Measurement of Cutaneous Inflammation: Estimation of Neutrophil Content with an Enzyme Marker

1982 • 3,566 citations

Hapten-Induced Model of Chronic Inflammation and Ulceration in the Rat Colon

1989 • 1,681 citations

Annexins: the problem of assessing the biological role for a gene family of multifunctional calcium- and phospholipid-binding proteins

1994 • 1,113 citations

The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes.

1990 • 940 citations

Anti-inflammatory actions of steroids: molecular mechanisms

1993 • 740 citations

Hapten-induced model of chronic inflammation and ulceration in the rat colon

1989 • 706 citations

Cloning and expression of human lipocortin, a phospholipase A2 inhibitor with potential anti-inflammatory activity

1986 • 671 citations

UV-Assay with Pyruvate and NADH

1974 • 580 citations

Lipocortin and the mechanism of action of the glucocorticoids

1988 • 499 citations

Glucocorticoids inhibit the induction of nitric oxide synthase in macrophages

1990 • 455 citations

Lipocortin-1: cellular mechanisms and clinical relevance

1994 • 383 citations

A novel pathway for secretory proteins?

1990 • 292 citations

Modulation of IL-1-induced neutrophil migration by dexamethasone and lipocortin 1.

1993 • 223 citations

Ectocytosis caused by sublytic autologous complement attack on human neutrophils. The sorting of endogenous plasma-membrane proteins and lipids into shed vesicles

1991 • 219 citations

Annexin I is phosphorylated in the multivesicular body during the processing of the epidermal growth factor receptor.

1993 • 210 citations

Purification and partial sequence analysis of a 37-kDa protein that inhibits phospholipase A2 activity from rat peritoneal exudates.

1986 • 204 citations

Human recombinant lipocortin 1 has acute local anti-inflammatory properties in the rat paw edema test.

1989 • 204 citations

Anti-inflammatory lipocortin 1 production by peripheral blood leucocytes in response to hydrocortisone

1990 • 186 citations

Selective secretion of annexin 1, a protein without a signal sequence, by the human prostate gland

1991 • 184 citations

Recombinant human lipocortin 1 inhibits thromboxane release from guinea-pig isolated perfused lung

1987 • 166 citations

Lipocortin-1 is an endogenous inhibitor of ischemic damage in the rat brain.

1991 • 134 citations

The mechanism of matrix vesicle formation. Studies on the composition of chondrocyte microvilli and on the effects of microfilament-perturbing agents on cellular vesiculation.

1987 • 134 citations

Treatment With 16, 16'-Dimethyl Prostaglandin E2 Before and After Induction of Colitis With Trinitrobenzenesulfonic Acid in Rats Decreases Inflammation

1989 • 130 citations

Biosynthesis, secretion and extracellular localization of anchorin CII, a collagen-binding protein of the calpactin family.

1988 • 122 citations

Relation of peroxidase activity in gut mucosa to inflammation

1978 • 118 citations

Enhanced expression of group II phospholipase A₂ gene in the tissues of endotoxin shock rats and its suppression by glucocorticoid

1990 • 111 citations

Identification of Phospholipid-dependent Calcium-binding Proteins as Constituents of Matrix Vesicles

1989 • 110 citations

Inhibition of O2- generation by dexamethasone is mimicked by lipocortin I in alveolar macrophages.

1989 • 108 citations

Dexamethasone induces the expression of the mRNA of lipocortin 1 and 2 and the release of lipocortin 1 and 5 in differentiated, but not undifferentiated U‐937 cells

1991 • 104 citations

Expression of annexins on the surfaces of non-metastatic and metastatic human and rodent tumor cells

1993 • 102 citations

Lipocortin 1 Mediates an Early Inhibitory Action of Glucocorticoids on the Secretion of ACTH by the Rat Anterior Pituitary Gland in vitro

1993 • 100 citations

Annexin 3 is associated with cytoplasmic granules in neutrophils and monocytes and translocates to the plasma membrane in activated cells

1994 • 86 citations

Annexin I-mediated vesicular aggregation: mechanism and role in human neutrophils

1992 • 84 citations

Interleukin Iβ and thioredoxin are secreted through a novel pathway of secretion

1991 • 80 citations

Ketotifen effectively prevents mucosal damage in experimental colitis.

1992 • 80 citations

A purified lipocortin shares the anti‐inflammatory effect of glucocorticosteroids in vivo in mice

1989 • 78 citations

Detection of Lipocortin 1 in Human Lung Lavage Fluid: Lipocortin Degradation As a Possible Proteolytic Mechanism in the Control of Inflammatory Mediators and Inflammation

1990 • 75 citations

Modulation of the Hypothalamo-Pituitary-Adrenocortical Responses to Cytokines in the Rat by Lipocortin 1 and Glucocorticoids: A Role for Lipocortin 1 in the Feedback Inhibition of CRF-41 Release?

1993 • 56 citations

Adrenalectomy decreases lipocortin-I messenger ribonucleic acid and tissue protein content in rats.

1992 • 55 citations

Glucocorticoids inhibit TNFα-induced cytosolic phospholipase A2 activity

1992 • 52 citations

Lipocortins (annexins) 1, 2, 4 and 5 are increased in the central nervous system in multiple sclerosis

1992 • 50 citations

Lipocortin-derived peptides

1994 • 49 citations

Corticosteroids increase lipocortin I in BAL fluid from normal individuals and patients with lung disease

1990 • 49 citations

Inhibition of eicosanoid and PAF formation by dexamethasone in rat inflammatory polymorphonuclear neutrophils may implicate lipocortin ‘s’

1988 • 45 citations

Identification and characterization of phospholipase A₂ inhibitory proteins in human mononuclear cells

1990 • 42 citations

Further characterization of four lipocortins from human peripheral blood mononuclear cells

1989 • 35 citations

Localization of annexins in normal and diseased human skin

1993 • 26 citations

Conceivable difference in the anti‐inflammatory mechanisms of lipocortins 1 and 5

1993 • 26 citations

Inhibition of phospholipase A2 activity of guinea-pig alveolar macrophages by lipocortin-like proteins purified from mice lung

1988 • 26 citations

Up-regulation of lipocortin-1 and its mRNA in reactive astrocytes in kainate-lesioned rat cerebellum

1994 • 20 citations

Rapid purification of two lipocortin-like proteins from mice lung

1988 • 13 citations

Lipocortin-present perforating and lipocortin-absent nonperforating Crohn's disease

1992 • 13 citations

Annexin 1 regulation in human epidermal cells.

1994 • 11 citations