Radioprotection by WR-2721 in vitro at low oxygen tensions: Implications for its mechanisms of action

Active versus passive absorption kinetics as the basis for selective protection of normal tissues by S-2-(3-aminopropylamino)-ethylphosphorothioic acid.

1980 • 300 citations

Radiation response of multicell spheroids--an in vitro tumour model.

1976 • 236 citations

Radiosensitization of Hypoxic Tumor Cells by Depletion of Intracellular Glutathione

1982 • 176 citations

Radiobiolgoical and biochemical studies of thiophosphate radioprotective compounds related to cysteamine.

1971 • 135 citations

Interaction of Cultured Mammalian Cells with WR-2721 and Its Thiol, WR-1065: Implications for Mechanisms of Radioprotection

1983 • 132 citations

Distribution of 35 S-Labeled WR-2721 in Normal and Malignant Tissues of the Mouse

1976 • 97 citations

A Comparative Study of the Radioprotective Effects of Cysteamine, WR-2721, and WR-1065 in Cultured Human Cells

1979 • 82 citations

Variable Radiobiological Responses of Spheroids

1980 • 76 citations

Rationale for initial clinical trials and future development of radioprotectors.

1980 • 73 citations

Quantitation of the radiotherapeutic importance of naturally-hypoxic normal tissues from collated experiments with rodents using single doses

1979 • 56 citations

Correlation between the Radiobiological Oxygen Constant,K, and the Non-protein Sulphydryl Content of Mammalian Cells

1980 • 54 citations

Mammalian cell studies with diamide

1979 • 44 citations

Protective drugs in cancer therapy: Optimal clinical testing and future directions

1982 • 38 citations

In VitroEvaluation of Some Latent Radioprotective Compounds

1976 • 19 citations

In vitro studies on the absorption of WR-2721 by tumors and normal tissues

1982 • 11 citations