Gene Therapy for Human Genetic Disease?

Viral RNA-dependent DNA Polymerase: RNA-dependent DNA Polymerase in Virions of Rous Sarcoma Virus

1970 • 2,061 citations

Viral RNA-dependent DNA Polymerase: RNA-dependent DNA Polymerase in Virions of RNA Tumour Viruses

1970 • 1,992 citations

GENETICS OF HUMAN CELL LINES, IV. DNA-MEDIATED HERITABLE TRANSFORMATION OF A BIOCHEMICAL TRAIT

1962 • 493 citations

The integrated state of viral DNA in SV40-transformed cells.

1968 • 345 citations

Uptake of Protein by Mammalian Cells: An Underdeveloped Area

1968 • 290 citations

Transfer of Thymidine Kinase to Thymidine Kinaseless L Cells by Infection with Ultraviolet-Irradiated Herpes Simplex Virus

1971 • 268 citations

Total Synthesis of the Gene for an Alanine Transfer Ribonucleic Acid from Yeast

1970 • 262 citations

Oncogenic Viruses

1970 • 231 citations

Bacterial Virus Gene Expression in Human Cells

1971 • 204 citations

Cell Transformation by Viruses

1969 • 200 citations

Isolation of Pure lac Operon DNA*

1969 • 195 citations

Prenatal Genetic Diagnosis

1970 • 176 citations

Induced Degradation of Glycosaminoglycans in Hurler's and Hunter's Syndromes by Plasma Infusion

1971 • 161 citations

Enzyme Replacement in Fabry's Disease, an Inborn Error of Metabolism

1970 • 130 citations

Factors associated with long-term survival of diabetics

1970 • 117 citations

Correction of a Genetic Defect in a Mammalian Cell

1971 • 113 citations

Effect of Leukocyte Transfusion in a Child with Type II Mucopolysaccharidosis

1971 • 101 citations

An Enzymatic Basis for Variation in Response to Allopurinol

1968 • 96 citations

LYSOSOMES IN TYPE II GLYCOGENOSIS

1967 • 93 citations

Prospects for Genetic Intervention in Man

1970 • 93 citations

Characterization of a temperature-sensitive mutant of polyoma virus

1970 • 76 citations

Metachromatic Leukodystrophy

1969 • 75 citations

Formation of Different Hæmoglobins in Tissue Culture of Human Bone Marrow Treated with Human Deoxyribonucleic Acid

1961 • 67 citations

BACTERIAL TRANSFORMATION, WITH SPECIAL REFERENCE TO RECOMBINATION PROCESS

1970 • 58 citations

STUDIES OF THE MECHANISM OF ACTION OF THE SHOPE RABBIT PAPILLOMA VIRUS

1963 • 58 citations

Prenatal Genetic Diagnosis

1970 • 54 citations

Prenatal Genetic Diagnosis

1970 • 51 citations

A Cystic Fibrosis Pilot Survey in Three New England States

1962 • 50 citations

The Use of DNA for Gene Therapy—the Need, Experimental Approach, and Implications

1970 • 49 citations

Hyperargininemia with arginase deficiency a new familial metabolic disease

1970 • 49 citations

DNA and Gene Therapy: Uncoating of Polyoma Pseudovirus in Mouse Embryo Cells

1970 • 44 citations

DNA-Induced Transformation in Drosophila: Genetic Analysis of Transformed Stocks

1971 • 40 citations

Human Diploid Cell Transformation by DNA Extracted from the Tumor Virus SV40

1969 • 38 citations

Immunodiffusion studies on human liver and erythrocyte arginases

1965 • 32 citations

Regeneration of the Lens of the Eye in the Rabbit

1959 • 31 citations

Cerebral Lipidoses

1970 • 29 citations

On the arginase of the shope papillomas

1967 • 28 citations

Hyperarginin�mie mit Arginasedefekt Eine neue famili�re Stoffwechselst�rung

1970 • 26 citations

The SV40 Pseudovirus: Its Potential for General Transduction in Animal Cells

1970 • 26 citations

[Hyperargininemia with arginase deficiency. A new familial metabolic disease. II. Biochemical studies].

1970 • 24 citations

INDUCTION OF MELANIN SYNTHESIS IN ALBINO MOUSE SKIN BY DNA FROM PIGMENTED MICE

1969 • 24 citations

Dietary Treatment of Inborn Errors of Metabolism

1970 • 23 citations

Further observations on the role of the adenyl cyclase-cyclic AMP (CAMP) system in human lipolysis.

1971 • 23 citations

Evidence for Genetic Expression of Integrated DNA in Lymphoma Cells

1969 • 21 citations

DNA-mediated transformation of mammalian cells in culture. Increased transforming efficiency following sonication

1970 • 20 citations

Reconstitution of Viruses

1970 • 19 citations

HUMAN GENETICS

1970 • 18 citations

CHANGE IN THE STRUCTURE OF SHOPE PAPILLOMA VIRUS-INDUCED ARGINASE ASSOCIATED WITH MUTATION OF THE VIRUS

1971 • 13 citations

Studies on the arginase activity of Shope papilloma: Possible presence of isozymes

1967 • 12 citations

Specific metabolic changes in DNA-treated L1210 leukemia cells.

1967 • 8 citations

Lasting changes in acriflavine-binding induced in mammalian cells by exogenous DNA

1968 • 8 citations