Restriction fragment length polymorphism of DQ and DR class II genes of the bovine major histocompatibility complex

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

The sampling theory of selectively neutral alleles

1972 • 2,158 citations

MHC-Restricted Cytotoxic T Cells: Studies on the Biological Role of Polymorphic Major Transplantation Antigens Determining T-Cell Restriction-Specificity, Function, and Responsiveness

1979 • 1,969 citations

Evolution of genes and proteins.

1983 • 1,224 citations

Role of MHC Gene Products in Immune Regulation

1981 • 705 citations

THE HOMOZYGOSITY TEST OF NEUTRALITY

1978 • 689 citations

Restriction sites containing CpG show a higher frequency of polymorphism in human DNA

1984 • 586 citations

Evolutionary Significance of the HL-A System

1972 • 523 citations

The natural history of the major histocompatibility complex

1987 • 468 citations

EVIDENCE FOR BALANCING SELECTION AT HLA

1983 • 329 citations

Complete amino acid sequence of an HLA-DR antigen-like beta chain as predicted from the nucleotide sequence: similarities with immunoglobulins and HLA-A, -B, and -C antigens.

1982 • 320 citations

Gene organization and recombinational hotspots in the murine major histocompatibility complex

1986 • 312 citations

Mutations and selection in the generation of class II histocompatibility antigen polymorphism.

1984 • 232 citations

Both alpha and beta chains of HLA-DC class II histocompatibility antigens display extensive polymorphism in their amino-terminal domains.

1984 • 190 citations

Class II genes of the human major histocompatibility complex. Organization and evolutionary relationship of the DR beta genes.

1987 • 186 citations

Alpha chain of HLA-DR transplantation antigens is a member of the same protein superfamily as the immunoglobulins

1982 • 168 citations

CG dinucleotide clusters in MHC genes and in 5′ demethylated genes

1984 • 146 citations

Characterization of the MHC class II region in cattle. The number of DQ genes varies between haplotypes

1988 • 139 citations

Linkage relationships in the bovine MHC region. High recombination frequency between class II subregions

1988 • 135 citations

Genomic hybridization of bovine class II major histocompatibility genes: 1. Extensive polymorphism of DQα and DQβ genes

1986 • 107 citations

Genomic hybridization of bovine class II major histocompatibility genes: 2. Polymorphism of DR genes and linkage disequilibrium in the DQ‐DR region

1986 • 87 citations

Contrasting evolutionary histories among tightly linked HLA loci.

1986 • 83 citations

Linkage in cattle between the major histocompatibility complex (BoLA) and the M blood group system

1984 • 45 citations

Lymphocyte-Defined Loci in Cattle

1977 • 43 citations

Gene clusters and the evolution of the major histocompatibility system

1986 • 26 citations

Genetic Polymorphism of a Bovine t-Complex Gene (TCP1) Linkage to Major Histocompatibility Genes

1988 • 23 citations

Is allograft rejection a clue to the mechanism promoting MHC polymorphism?

1987 • 12 citations

Lactate Dehydrogenase lsozymes in Barley: Polymorphism and Genetic Basis

1988 • 11 citations

The significance of immunity restriction by the major histocompatibility complex, and of the occurrence of high polymorphism at MHC loci: Two hypotheses

1981 • 8 citations