Lipoprotein(a). A unique risk factor for atherothrombotic disease.

cDNA sequence of human apolipoprotein(a) is homologous to plasminogen

1987 • 1,842 citations

Intracellular Protein Degradation in Mammalian and Bacterial Cells

1974 • 1,775 citations

Increased Plasma Levels of a Rapid Inhibitor of Tissue Plasminogen Activator in Young Survivors of Myocardial Infarction

1985 • 1,364 citations

Kinetics of the activation of plasminogen by human tissue plasminogen activator. Role of fibrin.

1982 • 1,300 citations

A NEW SERUM TYPE SYSTEM IN MAN—THE L_p SYSTEM

1963 • 1,292 citations

The Mysteries Of Lipoprotein(a)

1989 • 1,247 citations

Association of levels of lipoprotein Lp(a), plasma lipids, and other lipoproteins with coronary artery disease documented by angiography.

1986 • 933 citations

Lp(a) glycoprotein phenotypes. Inheritance and relation to Lp(a)-lipoprotein concentrations in plasma.

1987 • 884 citations

Lp(a) Lipoprotein as a Risk Factor for Myocardial Infarction

1986 • 779 citations

Lipoprotein(a) modulation of endothelial cell surface fibrinolysis and its potential role in atherosclerosis

1989 • 696 citations

Lipoprotein Lp(a) and the risk for myocardial infarction

1981 • 693 citations

A potential basis for the thrombotic risks associated with lipoprotein(a)

1989 • 585 citations

Lipoprotein(a), fibrin binding, and plasminogen activation.

1990 • 460 citations

Detection and quantification of lipoprotein(a) in the arterial wall of 107 coronary bypass patients.

1989 • 455 citations

Human plasma lipoprotein [a]. Structural properties.

1983 • 448 citations

Partial amino acid sequence of apolipoprotein(a) shows that it is homologous to plasminogen.

1987 • 411 citations

HMG CoA reductase inhibitors lower LDL cholesterol without reducing Lp(a) levels.

1989 • 336 citations

The effect of thrombocytopenia on experimental arteriosclerotic lesion formation in rabbits. Smooth muscle cell proliferation and re-endothelialization.

1977 • 292 citations

Plasmin catalyzes binding of lipoprotein (a) to immobilized fibrinogen and fibrin.

1989 • 286 citations

Heterogeneity of human plasma lipoprotein (a). Isolation and characterization of the lipoprotein subspecies and their apoproteins.

1984 • 282 citations

Radioimmunoassay of human plasma Lp(a) lipoprotein

1977 • 274 citations

Genetics of the quantitative Lp(a) lipoprotein trait

1989 • 272 citations

Physicochemical properties of apolipoprotein(a) and lipoprotein(a-) derived from the dissociation of human plasma lipoprotein (a).

1986 • 272 citations

Levels of lipoprotein Lp(a) decline with neomycin and niacin treatment

1985 • 270 citations

Serum Lp(a) level as a predictor of vein graft stenosis after coronary artery bypass surgery in patients.

1988 • 255 citations

Quantitation and localization of apolipoproteins [a] and B in coronary artery bypass vein grafts resected at re-operation.

1989 • 254 citations

Relationship of plasma lipoprotein Lp(a) levels to race and to apolipoprotein B.

1985 • 242 citations

Defects in the low density lipoprotein receptor gene affect lipoprotein (a) levels: multiplicative interaction of two gene loci associated with premature atherosclerosis.

1989 • 239 citations

Teaching old dogmas new tricks

1987 • 236 citations

Localization of Individual Lysine‐Binding Regions in Human Plasminogen and Investigations on Their Complex‐Forming Properties

1980 • 224 citations

Studies on the role of specific cell surface receptors in the removal of lipoprotein (a) in man.

1983 • 211 citations

Genetics of the quantitative Lp(a) lipoprotein trait

1988 • 211 citations

Lp(a) lipoprotein as a risk factor for myocardial infarction

1986 • 203 citations

Rhesus Monkey Apolipoprotein(a)

1989 • 182 citations

Plasma Ip(a) concentration is inversely correlated with the ratio of Kringle IV/Kringle V encoding domains in the apo(a) gene.

1989 • 159 citations

The cell-binding domains of plasminogen and their function in plasma.

1988 • 134 citations

A study of methods of identification and estimation of LP(a) lipoprotein and of its significance in health, hyperlipidaemia and atherosclerosis

1974 • 133 citations

Enzyme-linked immunoassay for Lp[a].

1989 • 131 citations

The apolipoprotein(a) gene resides on human chromosome 6q26?27, in close proximity to the homologous gene for plasminogen

1988 • 130 citations

Fat feeding in humans induces lipoproteins of density less than 1.006 that are enriched in apolipoprotein [a] and that cause lipid accumulation in macrophages.

1986 • 125 citations

Isolation of apolipoprotein(a) from lipoprotein(a).

1985 • 124 citations

Lipoprotein a inhibits streptokinase-mediated activation of human plasminogen

1989 • 116 citations

Lipoprotein(a) binds to fibronectin and has serine proteinase activity capable of cleaving it.

1989 • 115 citations

Lipoprotein (a) and plasminogen are immunochemically related

1988 • 112 citations

Serum Lipids in Angiographically Assessed Coronary Atherosclerosis

1978 • 99 citations

Location of the intermediate and high affinity omega-aminocarboxylic acid-binding sites in human plasminogen.

1982 • 97 citations

Uptake of Lp(a) lipoprotein by cultured fibroblasts

1981 • 96 citations

Genetic linkage between lipoprotein(a) phenotype and a DNA polymorphism in the plasminogen gene

1988 • 91 citations

The genetics of the Lp Antigen

1974 • 84 citations

Lp(a) phenotypes, other lipoprotein parameters, and a family history of coronary heart disease in middle‐aged males

1979 • 84 citations

Lysine/fibrin binding sites of kringles modeled after the structure of kringle 1 of prothrombin

1988 • 81 citations

ATHEROGENESIS AND PLASMA CONSTITUENTS. I. DEMONSTRATION OF FIBRIN IN THE WHITE PLAQUE BY THE FLUORESCENT ANTIBODY TECHNIQUE.

1964 • 77 citations

Electron microscopy of fibrin in human atherosclerotic lesions

1965 • 74 citations

Quantitative genetic studies of the human plasma Lp(a) lipoprotein

1974 • 73 citations

The genetics of quantitative plasma Lp(a): Analysis of a large pedigree

1983 • 68 citations

Studies of Lp-Lipoprotein as a Quantitative Genetic Trait

1970 • 66 citations

CHARACTERIZATION OF THE Lp(a) LIPOPROTEIN IN HUMAN PLASMA

1970 • 59 citations

Serum lipoprotein patterns in patients with coronary atherosclerosis

1973 • 41 citations

Structural and functional changes of rhesus serum low density lipoproteins during cycles of diet-induced hypercholesterolemia.

1982 • 39 citations

The linkage with apolipoprotein (a) in lipoprotein (a) modifies the immunochemical and functional properties of apolipoprotein B

1988 • 36 citations

Beitrag zur Problematik des Lp-Systems

1966 • 31 citations

Proton NMR studies of aliphatic ligand binding to human plasminogen kringle 4

1989 • 31 citations

Immunochemical characterization of a low affinity lysine binding site within plasminogen.

1981 • 23 citations

In vivo studies on the binding sites for lipoprotein (a) on parenchymal and non‐parenchymal rat liver cells

1988 • 18 citations

The binding of antifibrinolytic amino acids to kringle-4-containing fragments of plasminogen

1984 • 18 citations

Lp(a) and the Fibrinolytic System

1990 • 13 citations

Quantitative Genetic Studies of the Human Plasma Lp(a) Lipoprotein

1974 • 7 citations

Serum Lp(a) level as a predictor of vein graft stenosis after coronary artery bypass surgery in patients

1989 • 6 citations