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Identification of 19 (R)-OH prostaglandin E2 as a selective prostanoid EP2-receptor agonist

Data up to Jan 2025

Published1993
Citations34
References31

Total Citations Per Year

Abstract

References (31)

Advances in prostaglandin, thromboxane, and leukotriene research

1985 • 759 citations

Comparison of the effects of prostacyclin (PGI2), prostaglandin E1 and D2 on platelet aggregation in different species

1978 • 339 citations

The classification of prostaglandin DP‐receptors in platelets and vasculature using BW A868C, a novel, selective and potent competitive antagonist

1989 • 196 citations

Prostaglandin E receptor subtypes in smooth muscle: agonist activities of stable prostacyclin analogues

1986 • 167 citations

Prostanoid receptors — the development of a working classification

1984 • 150 citations

Characterization of prostanoid relaxant/inhibitory receptors (ψ) using a highly selective agonist, TR4979

1986 • 149 citations

ANTAGONISM OF THE THROMBOXANE‐SENSITIVE CONTRACTILE SYSTEMS OF THE RABBIT AORTA, DOG SAPHENOUS VEIN AND GUINEA‐PIG TRACHEA

1982 • 142 citations

Transformation of prostaglandin D2 to 9 alpha, 11 beta-(15S)-trihydroxyprosta-(5Z,13E)-dien-1-oic acid (9 alpha, 11 beta-prostaglandin F2): a unique biologically active prostaglandin produced enzymatically in vivo in humans.

1985 • 136 citations

19-HydroxyIated E prostaglandins as the major prostaglandins of human semen

1974 • 135 citations

Evidence for distinct prostaglandin I2 and D2 receptors in human platelets.

1979 • 118 citations

In vitro characterization of prostanoid EP‐receptors in the non‐pregnant human myometrium

1991 • 100 citations

Antagonism of prostaglandin E2 by 1-acetyl-2-(8-chloro-10,11-dihydrodibenz (b,f) (1,4) oxazepine-10-carbonyl) hydrazine (SC-19220).

1969 • 93 citations

Studies on the ocular pharmacology of prostaglandin D2.

1990 • 86 citations

New evidence with selective agonists and antagonists for the subclassification of PGE2-sensitive (EP) receptors.

1987 • 85 citations

Characterisation of the prostanoid receptors mediating contraction of guinea-pig isolated trachea

1985 • 83 citations

Suppression of natural killer cell activity by human seminal plasma in vitro: identification of 19-OH-PGE as the suppressor factor.

1986 • 64 citations

Evidence for homogeneity of thromboxane A2 receptor using structurally different antagonists

1988 • 60 citations

Origin of prostaglandins in human semen

1982 • 49 citations

The antagonism by BW A868C of PGD2 and BW245C activation of human platelet adenylate cyclase

1989 • 47 citations

Prostaglandin concentrations in the semen of hypogonadal men during treatment with testosterone

1976 • 39 citations

Prostanoid-induced blood-aqueous barrier breakdown in rabbits involves the EP2 receptor subtype.

1990 • 36 citations

Quantification of prostaglandins in human seminal fluid

1982 • 33 citations

On the multiplicity of platelet prostaglandin receptors

1984 • 29 citations

Biochemical characterization of prostaglandin 19-hydroxylase of seminal vesicles.

1988 • 29 citations

On the origin of prostaglandins in human seminal fluid

1985 • 25 citations

Effects of 19-hydroxy-prostaglandins on oviductal and uterine motility

1977 • 24 citations

Ca2+ transients evoked by prostanoids in Swiss 3T3 cells suggest an FP-receptor mediated response.

1991 • 23 citations

Rapid and slow hydroxylators of seminal E prostaglandins

1988 • 14 citations

Marked Differential Effects of Prostanoid Metabolites on Rabbit Intraocular Pressure

1989 • 7 citations

Relationship between prostaglandins in human seminal fluid and fertility.

1983 • 7 citations

Biosynthesis of 19-hydroxy and 20-hydroxy E prostaglandins in seminal fluids.

1987 • 2 citations

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Identification of 19 (R)-OH prostaglandin E2 as a selective prostanoid EP2-receptor… (1993) – Prostaglandins | Metascience Observatory Explorer