Germline mutations in WTX cause a sclerosing skeletal dysplasia but do not predispose to tumorigenesis

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

2001 • 156,143 citations

Wnt/β-Catenin Signaling in Development and Disease

2006 • 5,286 citations

qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data.

2007 • 3,701 citations

A census of human cancer genes

2004 • 3,190 citations

Tumor Suppressor Genes

1991 • 1,784 citations

High Bone Density Due to a Mutation in LDL-Receptor–Related Protein 5

2002 • 1,577 citations

Wnt/β-Catenin Signaling in Mesenchymal Progenitors Controls Osteoblast and Chondrocyte Differentiation during Vertebrate Skeletogenesis

2005 • 1,536 citations

Canonical Wnt Signaling in Differentiated Osteoblasts Controls Osteoclast Differentiation

2005 • 1,493 citations

Sclerostin Binds to LRP5/6 and Antagonizes Canonical Wnt Signaling

2005 • 1,294 citations

A Mutation in the LDL Receptor–Related Protein 5 Gene Results in the Autosomal Dominant High–Bone-Mass Trait

2002 • 1,279 citations

Canonical WNT Signaling Promotes Osteogenesis by Directly Stimulating Runx2 Gene Expression

2005 • 1,092 citations

Distinct roles for Hedgehog and canonical Wnt signaling in specification,differentiation and maintenance of osteoblast progenitors

2006 • 956 citations

A Robust Algorithm for Copy Number Detection Using High-Density Oligonucleotide Single Nucleotide Polymorphism Genotyping Arrays

2005 • 651 citations

Essential Role of β-Catenin in Postnatal Bone Acquisition

2005 • 570 citations

Deletion of a Single Allele of the Dkk1 Gene Leads to an Increase in Bone Formation and Bone Mass

2006 • 517 citations

High Bone Mass in Mice Expressing a Mutant LRP5 Gene

2003 • 494 citations

Lrp5-independent activation of Wnt signaling by lithium chloride increases bone formation and bone mass in mice

2005 • 487 citations

The Wnt Antagonist Secreted Frizzled-Related Protein-1 Is a Negative Regulator of Trabecular Bone Formation in Adult Mice

2004 • 439 citations

Wilms Tumor Suppressor WTX Negatively Regulates WNT/ß-Catenin Signaling

2007 • 393 citations

An X Chromosome Gene, WTX , Is Commonly Inactivated in Wilms Tumor

2007 • 330 citations

Deficiency of PORCN, a regulator of Wnt signaling, is associated with focal dermal hypoplasia

2007 • 276 citations

Wnt10b Increases Postnatal Bone Formation by Enhancing Osteoblast Differentiation

2007 • 267 citations

Mutations in X-linked PORCN, a putative regulator of Wnt signaling, cause focal dermal hypoplasia

2007 • 264 citations

Wilms tumor genetics: Mutations in WT1, WTX, and CTNNB1 account for only about one‐third of tumors

2008 • 198 citations

Osteoblasts Directly Control Lineage Commitment of Mesenchymal Progenitor Cells through Wnt Signaling

2007 • 156 citations

Multiple roles of mesenchymal β-catenin during murine limb patterning

2006 • 127 citations

AMER1 regulates the distribution of the tumor suppressor APC between microtubules and the plasma membrane

2007 • 88 citations

Functional inactivation of the WTX gene is not a frequent event in Wilms’ tumors

2008 • 71 citations

OSTEOPATHIA STRIATA—VOORHOEVE'S DISEASE

1953 • 60 citations

Osteopathia striata with cranial sclerosis: literature reappraisal argues for X-linked inheritance.

2000 • 29 citations

Deleted Work

1955 • 0 citations