The Concept of Critical Levels of Toxic Heavy Metals in Target Tissues
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Total Citations Per Year
Abstract
References (63)
Cadmium and health : a toxicological and epidemiological appraisal
1985 • 487 citations
Effects and dose-response relationships of toxic metals
1977 • 448 citations
Glutathione, a first line of defense against cadmium toxicity
1987 • 388 citations
Handbook of experimental pharmacology
1973 • 345 citations
Clinical Chemistry and Chemical Toxicology of Metals
1978 • 323 citations
Effect of Cadmium Salts on Testicular Tissue
1956 • 323 citations
Low-Level Fetal Lead Exposure Effect on Neurobehavioral Development in Early Infancy
1987 • 311 citations
Mercury, Mercurials and Mercaptans
1974 • 282 citations
Cadmium-induced hepatic and renal injury in chronically exposed rats: Likely role of hepatic cadmium-metallothionein in nephrotoxicity
1985 • 277 citations
The Behavior and Chemical Toxicity of U in the Kidney
1989 • 262 citations
Exposure and accumulation of cadmium in populations from Japan, the United States, and Sweden
1979 • 204 citations
Health hazards in the manufacture of alkaline accumulators with special reference to chronic cadmium poisoning; a clinical and experimental study.
1950 • 197 citations
Another Case of Hyperglobulinemia and Affection of the Central Nervous System1
1950 • 191 citations
RENAL TUBULAR MALFUNCTION AND PULMONARY EMPHYSEMA IN CADMIUM PIGMENT WORKERS
1963 • 176 citations
Renal Damage After Prolonged Exposure to Cadmium
1966 • 173 citations
Lead Dosage and the Role of the Intranuclear Inclusion Body
1970 • 168 citations
Effect of Cadmium Salts on Testicular Tissue
1956 • 162 citations
Significance of cadmium concentration in blood and in urine in workers exposed to cadmium
1979 • 138 citations
Critical concentrations of cadmium in human renal cortex: Dose‐effect studies in cadmium smelter workers
1981 • 102 citations
Aminoaciduria as a manifestation of renal tubular injury in lead intoxication and a comparison with patterns of aminoaciduria seen in other diseases
1962 • 100 citations
Factors Influencing Metabolism and Toxicity of Metals: A Consensus Report
1978 • 96 citations
Dosage-dependent disposition of cadmium administered orally to rats
1986 • 95 citations
Effects of Cadmium Exposure in Humans
1986 • 93 citations
Hazard Assessment of Chemicals
1985 • 90 citations
The critical level of cadmium in human renal cortex: A reevaluation
1983 • 84 citations
Factors influencing metabolism and toxicity of metals: a consensus report
1978 • 79 citations
Lead and the Kidney
1971 • 71 citations
Exposure and accumulation of cadmium in populations from Japan, the United States, and Sweden
1979 • 68 citations
Data on Man
1973 • 66 citations
Erythrocyte lead-binding protein after occupational exposure
1980 • 66 citations
Conceptual problems in establishing the critical concentration of cadmium in human kidney cortex
1984 • 61 citations
Absorption of Cadmium
1986 • 59 citations
The effect of dose on the disposition of lead in rats after intravenous and oral administration
1981 • 55 citations
Protective Effect of Thiol Compounds Against Cadmium-Induced Vascular Damage to Testis.
1966 • 50 citations
Reaction between Catalase and Hydrogen Peroxide
1948 • 50 citations
Erythrocyte lead‐binding protein after occupational exposure. II. Influence on lead inhibition of membrane Na+,K+‐adenosinetriphosphatase
1981 • 48 citations
Cadmium-Its in vivo detection in man
1975 • 47 citations
Effects of heavy metals on renal aspartate transport and the nature of solute movement in kidney cortex slices
1971 • 46 citations
Critical concentration of ‘unbound’ cadmium in the rabbit renal cortex
1986 • 46 citations
Some effects of uranyl acetate on proximal tubular function in rabbit kidney
1968 • 44 citations
Acute cadmium uptake by rabbit kidneys: Mechanism and effects
1990 • 40 citations
The dose-dependent deposition of cadmium into organs of Japanese quail following oral administration
1988 • 38 citations
Tissue metallothioneins in rabbits chronically exposed to cadmium, with special reference to the critical concentration of cadmium in the renal cortex.
1982 • 36 citations
Acute effects of cadmium on proximal tubular function in rabbits
1974 • 36 citations
The impact of air-lead on blood-lead in man—A critique of the recent literature
1981 • 29 citations
Kidney and bone retention functions in the human metabolism of uranium
1974 • 26 citations
Effects of uranium on rabbit renal tubules
1970 • 22 citations
Effect of age on cadmium-induced metallothionein synthesis in the rat
1988 • 21 citations
Transfer of liver cadmium to the kidney after aflatoxin induced liver damage
1980 • 21 citations
Does a critical concentration of cadmium in human renal cortex exist?
1977 • 21 citations
Protection against cadmium toxicity by zinc: Decrease in the Cd-high molecular weight protein fraction in rat liver and kidney on Zn pretreatment
1986 • 21 citations
Cadmium and the Cardiovascular System
1986 • 20 citations
Acute renal dysfunction by cadmium injected with cysteine in relation to renal critical concentration of cadmium
1986 • 16 citations
Cadmium found in non-soluble fraction of kidney homogenates and its relation to renal dysfunction after cadmium-cysteine administration
1985 • 13 citations
Specificity of acute effects of Cd on renal function
1984 • 10 citations
Effects and dose-response relationships of toxic metals : proceedings from an international meeting organized by the Subcommittee on the Toxicology of Metals of the Permanent Commission and International Association on Occupational Health, Tokyo, November 18-23, 1974
1976 • 10 citations
Kinetics of renal aspartate reabsorption and its inhibition by metals in the intact rat kidney
1985 • 7 citations
The critical level of cadmium in renal cortex: the concept and its limitations
1986 • 6 citations
The Effect of Dietary Selenium on Cadmium Cardiotoxicity
1986 • 6 citations
Nephrotoxicity of Uranyl Fluoride and Reversibility of Renal Injury in the Rat
1989 • 5 citations
A Model for Scaling the Results of U Excretion Rate Studies in Beagle Dogs to Man
1989 • 5 citations
Adaptation to Nephrotoxic Chemicals
1988 • 2 citations
Route, rate and nature of exposure as determinants of effects of heavy metals and other toxicants
1986 • 1 citations