The Role of Cytokines which Signal through the Common γ Chain Cytokine Receptor in the Reversal of HIV Specific CD4+ and CD8+ T Cell Anergy

Vigorous HIV-1-Specific CD4 ⁺ T Cell Responses Associated with Control of Viremia

1997 • 1,868 citations

T Cell Anergy

2003 • 1,418 citations

lnterleukin-2 programs mouse αβ T lymphocytes for apoptosis

1991 • 1,027 citations

HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors

2002 • 986 citations

Direct Visualization of Antigen-specific CD8+T Cells during the Primary Immune Response to Epstein-Barr Virus In Vivo

1998 • 902 citations

HIV-1-specific CD4+ T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression

1999 • 766 citations

Crosslinking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis.

1992 • 689 citations

IL-2, Regulatory T Cells, and Tolerance

2004 • 566 citations

Cytokine-driven Proliferation and Differentiation of Human Naive, Central Memory, and Effector Memory CD4+ T Cells

2001 • 538 citations

HIV-1 Viremia Prevents the Establishment of Interleukin 2–producing HIV-specific Memory CD4+ T Cells Endowed with Proliferative Capacity

2003 • 443 citations

Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi.

1998 • 431 citations

Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo

2003 • 384 citations

Reversal of in vitro T cell clonal anergy by IL-2 stimulation

1992 • 339 citations

The qualitative nature of the primary immune response to HIV infection is a prognosticator of disease progression independent of the initial level of plasma viremia

1997 • 282 citations

Impaired function of circulating HIV-specific CD8+ T cells in chronic human immunodeficiency virus infection

2000 • 273 citations

Maintenance of Large Numbers of Virus-Specific CD8+ T Cells in HIV-Infected Progressors and Long-Term Nonprogressors

2000 • 271 citations

High-level HIV-1 viremia suppresses viral antigen-specific CD4⁺T cell proliferation

2001 • 215 citations

A Significant Number of Human Immunodeficiency Virus Epitope-Specific Cytotoxic T Lymphocytes Detected by Tetramer Binding Do Not Produce Gamma Interferon

2000 • 201 citations

IL-15 mimics T cell receptor crosslinking in the induction of cellular proliferation, gene expression, and cytotoxicity in CD8⁺memory T cells

2002 • 199 citations

Diminished Proliferation of Human Immunodeficiency Virus-Specific CD4⁺T Cells Is Associated with Diminished Interleukin-2 (IL-2) Production and Is Recovered by Exogenous IL-2

2003 • 198 citations

Persistent numbers of tetramer+ CD8+ T cells, but loss of interferon-γ+ HIV-specific T cells during progression to AIDS

2002 • 186 citations

CD40 ligand-deficient mice generate a normal primary cytotoxic T-lymphocyte response but a defective humoral response to a viral infection

1996 • 154 citations

Primary Human Immunodeficiency Virus Type 1 Infection: Review of Pathogenesis and Early Treatment Intervention in Humans and Animal Retrovirus Infections

1993 • 150 citations

Cytomegalovirus (CMV)–Specific T Cell Immunity after Renal Transplantation Mediates Protection from CMV Disease by Limiting the Systemic Virus Load

1999 • 134 citations

Efficacy of Low‐Dose Subcutaneous Interleukin‐2 to Treat Advanced Human Immunodeficiency Virus Type 1 in Persons with ⩽250/μL CD4 T Cells and Undetectable Plasma Virus Load

1999 • 107 citations

Functional Impairment of Simian Immunodeficiency Virus-Specific CD8⁺T Cells during the Chronic Phase of Infection

2001 • 88 citations

HIV-1-Specific Memory CD4+ T Cells Are Phenotypically Less Mature Than Cytomegalovirus-Specific Memory CD4+ T Cells

2004 • 88 citations

Pilot Study of the Effects of Intermittent Interleukin‐2 on Human Immunodeficiency Virus (HIV)–Specific Immune Responses in Patients Treated during Recently Acquired HIV Infection

2002 • 83 citations

Characterization of HIV-1-specific T-helper cells in acute and chronic infection

1999 • 74 citations

The effects of natural altered peptide ligands on the whole blood cytotoxic T lymphocyte response to human immunodeficiency virus

1995 • 74 citations

Enhanced ELISPOT detection of antigen-specific T cell responses from cryopreserved specimens with addition of both IL-7 and IL-15—the Amplispot assay

2002 • 69 citations

Serum Cytokine Profiles in Acute Primary HIV-1 Infection and in Infectious Mononucleosis

1996 • 61 citations

HIV-1–specific CD4+ T lymphocyte turnover and activation increase upon viral rebound

2005 • 52 citations

HIV-1–specific CD4+ T lymphocyte turnover and activation increase upon viral rebound

2005 • 46 citations

Viro-immunological studies in acute HIV-1 infection

1994 • 37 citations

The acute retroviral syndrome and the pathogenesis of HIV-1 infection

1993 • 37 citations

Determinants of HIV-Specific CD8 T-cell responses in HIV-infected pediatric patients and enhancement of HIV-gag-specific responses with exogenous IL-15☆

2003 • 34 citations

Use of interleukin 15 to enhance interferon-γ production by antigen-specific stimulated lymphocytes from rhesus macaques

2003 • 27 citations

How HIV Evades CTL Recognition

2003 • 18 citations