The Role of CSF‐1 in Normal and Neoplastic Breast Physiology

Stat5a is mandatory for adult mammary gland development and lactogenesis.

1997 • 1,106 citations

Multiple hormone interactions in the developmental biology of the mammary gland.

1980 • 866 citations

Apparent role of the macrophage growth factor, CSF-1, in placental development

1987 • 506 citations

Structural alteration of viral homologue of receptor proto-oncogene fms at carboxyl terminus

1986 • 478 citations

Mammary plasminogen activator: correlation with involution, hormonal modulation and comparison between normal and neoplastic tissue

1979 • 437 citations

Biology and action of colony-stimulating factor-1

1997 • 430 citations

Macrophage growth factor CSF-1 stimulates human monocyte production of interferon, tumor necrosis factor, and colony stimulating activity.

1986 • 397 citations

Regulation of colony-stimulating factor 1 during pregnancy.

1986 • 314 citations

Urokinase-plasminogen activator, a new and independent prognostic marker in breast cancer.

1990 • 294 citations

A point mutation in the extracellular domain of the human CSF-1 receptor (c-fms proto-oncogene product) activates its transforming potential

1988 • 242 citations

Anti-Colony-Stimulating Factor-1 Antibody Staining in Primary Breast Adenocarcinomas Correlates With Marked Inflammatory Cell Infiltrates and Prognosis

1994 • 226 citations

The Biology of CSF-1 and Its Receptor

1992 • 216 citations

Development of the Human Mammary Gland

1987 • 199 citations

Proteinases of the mammary gland: developmental regulation in vivo and vectorial secretion in culture

1991 • 181 citations

Colony stimulating factor 1 is required for mammary gland development during pregnancy.

1994 • 177 citations

Activation of the feline c-fms proto-oncogene: Multiple alterations are required to generate a fully transformed phenotype

1988 • 164 citations

The Product of the c- fms Proto-Oncogene: a Glycoprotein with Associated Tyrosine Kinase Activity

1985 • 162 citations

Expression of colony-stimulating factor-1 in the human uterus and placenta

1992 • 161 citations

Ovarian adenocarcinomas express fms-complementary transcripts and fms antigen, often with coexpression of CSF-1.

1990 • 147 citations

A transmissible feline fibrosarcoma of viral origin.

1971 • 138 citations

Overexpression of epithelial macrophage colony-stimulating factor (CSF-1) and CSF-1 receptor: a poor prognostic factor in epithelial ovarian cancer, contrasted with a protective effect of stromal CSF-1.

1997 • 137 citations

Mutation of Tyr697, a GRB2-binding site, and Tyr721, a PI 3-kinase binding site, abrogates signal transduction by the murine CSF-1 receptor expressed in Rat-2 fibroblasts.

1993 • 136 citations

Constitutive production of macrophage colony-stimulating factor by human ovarian and breast cancer cell lines.

1989 • 135 citations

Regulation of Urokinase-Type Plasminogen Activator Gene Transcription by Macrophage Colony-Stimulating Factor

1995 • 130 citations

Epidermal Growth Factor Receptor, but Not c-erbB-2, Activation Prevents Lactogenic Hormone Induction of the β-Casein Gene in Mouse Mammary Epithelial Cells

1990 • 129 citations

FMS (CSF-1 receptor) and CSF-1 transcripts and protein are expressed by human breast carcinomas in vivo and in vitro.

1991 • 124 citations

CSF-1 and its receptor in breast carcinomas and neoplasms of the female reproductive tract

1997 • 121 citations

Impaired tumor growth in colony-stimulating factor 1 (CSF-1)-deficient, macrophage-deficientop/op mouse: Evidence for a role of CSF-1-dependent macrophages in formation of tumor stroma

1996 • 118 citations

Role of colony-stimulating factor-1 in reproduction and development

1997 • 110 citations

M‐CSF (monocyte colony stimulating factor) and M‐CSF receptor expression by breast tumour cells: M‐CSF mediated recruitment of tumour infiltrating monocytes?

1992 • 100 citations

Hormonal Regulation of Milk Protein Gene Expression

1989 • 100 citations

Expression of the macrophage colony-stimulating factor and its receptor in gynecologic malignancies

1991 • 99 citations

Endogenous receptor-bound urokinase mediates tissue invasion of human monocytes.

1989 • 96 citations

Expression of CSF-1/c-fms and SF/c-kit mRNA during preimplantation mouse development

1992 • 92 citations

Macrophage colony-stimulating factor (CSF-1) enhances invasiveness in CSF-1 receptor-positive carcinoma cell lines.

1992 • 89 citations

High level expression of fms proto-oncogene mRNA is observed in clinically aggressive human endometrial adenocarcinomas

1988 • 84 citations

Macrophage colony-stimulating factor mediates invasion of ovarian cancer cells through urokinase.

1995 • 84 citations

Expression of the Colony-Stimulating Factor-1 Receptor (c-fms Proto-Oncogene Product) in the Human Uterus and Placenta1

1992 • 80 citations

Uncoupling of the proliferation and differentiation signals mediated by the murine macrophage colony-stimulating factor receptor expressed in myeloid FDC-P1 cells.

1995 • 76 citations

Oncogene amplification correlates with dense lymphocyte infiltration in human breast cancers: A role for hematopoietic growth factor release by tumor cells?

1990 • 72 citations

Growth and differentiation signals regulated by the M-CSF receptor

1997 • 66 citations

Expression of transforming growth factors alpha and beta-1 messenger RNA in the bovine mammary gland during different stages of development and lactation

1997 • 66 citations

Colony-stimulating factor-1 in primary ascites of ovarian cancer is a significant predictor of survival

1993 • 63 citations

Identification of Macrophage Colony-Stimulating Factor in Human Milk and Mammary Gland Epithelial Cells

1995 • 60 citations

Lactation status influences expression of CCAAT/enhancer binding protein isoform mRNA in the mouse mammary gland

1998 • 58 citations

Isolation of v-fms and its human cellular homolog

1983 • 57 citations

The cytokine CSF-1 (M-CSF) expressed by endometrial carcinomas in vivo and in vitro, may also be a circulating tumor marker of neoplastic disease activity in endometrial carcinoma patients

1990 • 55 citations

Transcriptional regulation of the c-fms (CSF-1R) proto-oncogene in human breast carcinoma cells by glucocorticoids.

1995 • 53 citations

Prognostic significance of colony-stimulating factor receptor expression in ipsilateral breast cancer recurrence.

1998 • 53 citations

Expression of a viral oncoprotein during mammary gland development alters cell fate and function: induction of p53-independent apoptosis is followed by impaired milk protein production in surviving cells.

1996 • 47 citations

Recognition of activated CSF-1 receptor in breast carcinomas by a tyrosine 723 phosphospecific antibody

1997 • 43 citations

CSF-1 and c-fms gene expression in human carcinoma cell lines

1988 • 41 citations

Oncogene expression in vivo by ovarian adenocarcinomas and mixed-mullerian tumors.

1989 • 40 citations

Transformation of murine fibroblasts by a retrovirus encoding the murine c-fms proto-oncogene.

1989 • 35 citations

Expression of CSF-I and CSF-I receptor by normal lactating mammary epithelial cells

1998 • 34 citations

Changes in the phosphorylation states of connexin43 in myoepithelial cells of lactating rat mammary glands.

1997 • 32 citations

Understanding mammary gland development through the imbalanced expression of growth regulators

1996 • 25 citations

Random mutagenesis of CSF-1 receptor (FMS) reveals multiple sites for activating mutations within the extracellular domain.

1992 • 24 citations

Expression of Colony‐Stimulating Factor‐1 and Its Receptor (the Protein Product of c‐fms) in Invasive Breast Tumor Cells

1993 • 17 citations

Co‐expression of M‐CSF transcripts and protein, FMS (M‐CSF receptor) transcripts and protein, and steroid receptor content in adenocarcinomas of the ovary

1994 • 13 citations

Complex regulation of macrophage colony-stimulating factor in the HL-60 promyelocytic cell line.

1991 • 10 citations

Expression of neu Antigen in Normal Lactating and Prepartum Mammary Epithelial Cells

1995 • 5 citations

Clinical Application of Tissue and Serum Markers in Breast Cancer

2003 • 4 citations