Transcriptional Regulation of Proto-Oncogene c-fos

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

1987 • 3,057 citations

Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements

1987 • 2,107 citations

Regulation of Inducible and Tissue-Specific Gene Expression

1987 • 1,640 citations

The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter

1983 • 1,471 citations

Induction of c-fos gene and protein by growth factors precedes activation of c-myc

1984 • 1,463 citations

Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

1986 • 1,424 citations

Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene

1987 • 1,364 citations

Human Proto-Oncogene c- jun Encodes a DNA Binding Protein with Structural and Functional Properties of Transcription Factor AP-1

1987 • 1,353 citations

The c-fos protein interacts with c-JunAP-1 to stimulate transcription of AP-1 responsive genes

1988 • 1,352 citations

Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region

1985 • 1,244 citations

Role of ion flux in the control of c-fos expression

1986 • 1,006 citations

Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein

1984 • 949 citations

Oncogene jun encodes a sequence-specific trans- activator similar to AP-1

1988 • 940 citations

Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinate regulation with c-fos or c-myc.

1987 • 888 citations

Identification of a protein-binding site that mediates transcriptional response of the c-fos gene to serum factors

1986 • 883 citations

Transient accumulation of c-fos RNA following serum stimulation requires a conserved 5′ element and c-fos 3′ sequences

1985 • 871 citations

An RNA polymerase II transcription factor binds to an upstream element in the adenovirus major late promoter

1985 • 763 citations

Activation of the AIDS Retrovirus Promoter by the Cellular Transcription Factor, Sp1

1986 • 741 citations

Trans-acting protein factors and the regulation of eukaryotic transcription: lessons from studies on DNA tumor viruses.

1988 • 736 citations

Human CCAAT-binding proteins have heterologous subunits

1988 • 712 citations

FBJ murine osteosarcoma virus: identification and molecular cloning of biologically active proviral DNA

1982 • 668 citations

Fos-Associated Protein p39 Is the Product of the jun Proto-Oncogene

1988 • 643 citations

Transcriptional autoregulation of the proto-oncogene fos

1988 • 630 citations

Common DNA binding site for Fos protein complexesand transcription factor AP-1

1988 • 613 citations

c-fos protein can induce cellular transformation: A novel mechanism of activation of a cellular oncogene

1984 • 601 citations

Requirement for fos gene expression in the transcriptional activation of collagenase by other oncogenes and phorbol esters

1988 • 597 citations

Complexity of the early genetic response to growth factors in mouse fibroblasts.

1988 • 579 citations

Effect of protein synthesis inhibitors on growth factor activation of c-fos, c-myc, and actin gene transcription.

1986 • 548 citations

Differential expression of cellular oncogenes during pre- and postnatal development of the mouse

1982 • 540 citations

The Fos Complex and Fos-Related Antigens Recognize Sequence Elements That Co ntain AP-1 Binding Sites

1988 • 532 citations

Viral and cellular fos proteins: A comparative analysis

1984 • 523 citations

Nucleoprotein complexes that regulate gene expression in adipocyte differentiation: direct participation of c-fos

1987 • 523 citations

Multiple protein-binding sites in the 5'-flanking region regulate c-fos expression.

1986 • 516 citations

ADENOVIRUS PROMOTERS AND E1A TRANSACTIVATION

1986 • 460 citations

Calcium and growth factor pathways of c-fos transcriptional activation require distinct upstream regulatory sequences.

1988 • 404 citations

Identification and purification of a polypeptide that binds to the c-fos serum response element.

1987 • 398 citations

Adenovirus DNA replication in vitro: identification of a host factor that stimulates synthesis of the preterminal protein-dCMP complex.

1982 • 350 citations

Induction of c-fos during myelomonocytic differentiation and macrophage proliferation

1985 • 340 citations

Deregulated c-fos expression interferes with normal bone development in transgenic mice

1987 • 337 citations

Virus Induction of Osteosarcomas in Mice

1966 • 314 citations

Inducible binding of a factor to the c-fos enhancer

1986 • 310 citations

c-fos Sequence Necessary for Basal Expression and Induction by Epidermal Growth Factor, 12-O-Tetradecanoyl Phorbol-13-Acetate and the Calcium Ionophore

1987 • 304 citations

Differentiation of F9 teratocarcinoma stem cells after transfer of c-fos proto-oncogenes

1984 • 303 citations

Interaction of a common cellular transcription factor, ATF, with regulatory elements in both E1a- and cyclic AMP-inducible promoters.

1988 • 290 citations

Evidence of DNA: protein interactions that mediate HSV-1 immediate early gene activation by VP16.

1988 • 289 citations

Activation of the c-fos gene by UV and phorbol ester: different signal transduction pathways converge to the same enhancer element.

1988 • 271 citations

Viral and cellular fos proteins are complexed with a 39,000-dalton cellular protein.

1985 • 249 citations

The c-fos serum response element responds to protein kinase C-dependent and -independent signals but not to cyclic AMP.

1988 • 245 citations

Mutation of the c-fos gene dyad symmetry element inhibits serum inducibility of transcription in vivo and the nuclear regulatory factor binding in vitro.

1987 • 238 citations

DNA-bound Fos proteins activate transcription in yeast

1988 • 223 citations

Regulation of c-fosgene expression in hamster fibroblasts: initiation and elongation of transcription and mRNA degradation

1987 • 218 citations

Binding of the virion protein mediating alpha gene induction in herpes simplex virus 1-infected cells to its cis site requires cellular proteins.

1987 • 217 citations

Two different factors bind to the alpha-domain of the polyoma virus enhancer, one of which also interacts with the SV40 and c-fos enhancers.

1987 • 179 citations

The Adenovirus Major Late Transcription Factor Activates the Rat γ-Fibrinogen Promoter

1987 • 177 citations

Analysis of the differentiation-promoting potential of inducible c-fos genes introduced into embryonal carcinoma cells.

1985 • 173 citations

Expression of c-onc genes: c-fos transcripts accumulate to high levels during development of mouse placenta, yolk sac and amnion.

1983 • 171 citations

Identification of a Transcriptional Enhancer Element Upstream from the Proto-Oncogene fos

1985 • 171 citations

Inducible binding of a factor to the c-fos regulatory region.

1987 • 168 citations

Transcriptional activation encoded by the v-fos gene.

1986 • 161 citations

Interaction of GAL4 and GAL80 gene regulatory proteins in vitro.

1987 • 161 citations

Purification of the c-fos enhancer-binding protein.

1987 • 156 citations

The Heat Shock Response in HeLa Cells is Accompanied by Elevated Expression of the c-fos Proto-Oncogene

1987 • 147 citations

Proto-oncogene c-fos expression in growth regions of fetal bone and mesodermal web tissue

1987 • 133 citations

Wounding a fibroblast monolayer results in the rapid induction of the c-fos proto-oncogene.

1986 • 117 citations

Modulation of c-"os gene transcription by negative and positive cellular factors

1987 • 110 citations

Expression of c-fos in NIH3T3 cells is very low but inducible throughout the cell cycle.

1986 • 97 citations

Purification of intercalator-released p67, a polypeptide that interacts specifically with the c-fos serum response element

1987 • 92 citations

c-fos expression interferes with thymus development in transgenic mice

1988 • 84 citations

Structure-function analysis of fos protein: A single amino acid change activates the immortalizing potential of v-fos

1987 • 81 citations

Extended life span and tumorigenicity of nonestablished mouse connective tissue cells transformed by the fos oncogene of FBR-MuSV

1985 • 75 citations

Regulation of c-fos transcription in mouse fibroblasts: identification of DNase I-hypersensitive sites and regulatory upstream sequences.

1985 • 63 citations

Viral Etiology of Bone Cancer1

2015 • 56 citations

Expression of c-fos in parietal endoderm, amnion and differentiating F9 teratocarcinoma cells

1985 • 47 citations

The c-fos proto-oncogene in murine 3LL carcinoma clones controls the expression of MHC genes.

1988 • 26 citations

Induction of c-fosGene Expression by Interferons

1988 • 18 citations