Subcellular Distribution of Two Spin Trapping Agents in Rat Heart: Possible Explanation for Their Different Protective Effects Against Doxorubicin-Induced Cardiotoxicity

A clinicopathologic analysis of adriamycin cardiotoxicity

1973 • 1,534 citations

Adriamycin: The Role of Lipid Peroxidation in Cardiac Toxicity and Tumor Response

1977 • 1,116 citations

The Anthracycline Antineoplastic Drugs

1981 • 794 citations

Demonstration of free radical generation in "stunned" myocardium of intact dogs with the use of the spin trap alpha-phenyl N-tert-butyl nitrone.

1988 • 691 citations

Effect of anthracycline antibiotics on oxygen radical formation in rat heart.

1983 • 634 citations

Redox cycling of anthracyclines by cardiac mitochondria. I. Anthracycline radical formation by NADH dehydrogenase.

1986 • 608 citations

Molecular Pharmacology

1964 • 599 citations

Redox cycling of anthracyclines by cardiac mitochondria. II. Formation of superoxide anion, hydrogen peroxide, and hydroxyl radical.

1986 • 525 citations

Subcellular effects of adriamycin in the heart: A concise review

1987 • 463 citations

[2] Subcellular fractionation of rat liver

1974 • 438 citations

Stoichiometry of sodium-calcium exchange in cardiac sarcolemmal vesicles. Coupling to the sodium pump.

1979 • 407 citations

Anthracycline antibiotic augmentation of microsomal electron transport and free radical formation.

1977 • 365 citations

Adriamycin-induced free radical formation in the perfused rat heart: implications for cardiotoxicity.

1988 • 251 citations

Free radicals and reperfusion-induced arrhythmias: protection by spin trap agent PBN in the rat heart.

1987 • 179 citations

Problems associated with spin trapping oxygen-centered free radicals in biological systems

1989 • 148 citations

Cytofluorescence localization of adriamycin and daunorubicin.

1974 • 121 citations

Enzymatic activation and binding of adriamycin to nuclear DNA.

1984 • 94 citations

[24] Isolation of nuclei from liver and other tissues

1974 • 89 citations

Doxorubicin cardiotoxicity

1982 • 78 citations

Reperfusion-Induced Arrhythmias and Free Radicals

1987 • 71 citations

Identification of the site of adriamycin-activation in the heart cell

1988 • 43 citations

The production of hydroxyl radicals by adriamycin in red blood cells

1983 • 42 citations

Protective Effects of Spin-Trapping Agents on Adriamycin-Induced Cardiotoxicity in Isolated Rat Atria

1991 • 30 citations

Adriamycin uptake, intracellular binding and cytotoxicity in Chinese hamster ovary cells

1985 • 26 citations