Transvection and long‐distance gene regulation

Position-independent, high-level expression of the human β-globin gene in transgenic mice

1987 • 1,955 citations

How eukaryotic transcriptional activators work

1988 • 1,924 citations

Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites

1986 • 922 citations

Four Genes Responsible for a Position Effect on Expression From HML and HMR in Saccharomyces cerevisiae

1987 • 709 citations

Purification and cloning of a DNA binding protein from yeast that binds to both silencer and activator elements

1987 • 637 citations

Identification of a nonhistone chromosomal protein associated with heterochromatin in Drosophila melanogaster and its gene.

1986 • 618 citations

Cohabitation of scaffold binding regions with upstream/enhancer elements of three developmentally regulated genes of D. melanogaster

1986 • 587 citations

A glimpse at chromosomal order

1987 • 423 citations

A group of genes controlling the spatial expression of the bithorax complex in Drosophila

1985 • 413 citations

In vivo binding pattern of a trans-regulator of homoeotic genes in Drosophila melanogaster

1989 • 302 citations

The Theory and Application of a New Method of Detecting Chromosomal Rearrangements in Drosophila melanogaster

1954 • 280 citations

Genes controlling essential cell-cycle functions in Drosophila melanogaster.

1989 • 255 citations

Dependence of position-effect variegation in Drosophila on dose of a gene encoding an unusual zinc-finger protein

1990 • 229 citations

A new homeotic mutation in the Drosophila bithorax complex removes a boundary separating two domains of regulation.

1990 • 225 citations

Genetic analysis of the enhancer of zeste locus and its role in gene regulation in Drosophila melanogaster.

1990 • 209 citations

Spatial regulation of antennapedia and bithorax gene expression by the Polycomb locus in Drosophila

1986 • 204 citations

An enhancer stimulates transcription in Trans when attached to the promoter via a protein bridge

1989 • 202 citations

The Drosophila melanogaster suppressor of Hairy-wing protein binds to specific sequences of the gypsy retrotransposon.

1988 • 197 citations

A Bacterial Enhancer Functions to Tether a Transcriptional Activator Near a Promoter

1990 • 190 citations

Tissue-specific transcriptional enhancers may act in trans on the gene located in the homologous chromosome: the molecular basis of transvection in Drosophila.

1990 • 188 citations

The bithorax complex: control of segmental identity

1987 • 188 citations

RAP-1 factor is necessary for DNA loop formation in vitro at the silent mating type locus HML

1989 • 184 citations

Similarity Between the Transcriptional Silencer Binding Proteins ABF1 and RAP1

1989 • 180 citations

The yeast RAD50 gene encodes a predicted 153-kD protein containing a purine nucleotide-binding domain and two large heptad-repeat regions.

1989 • 139 citations

Position effect variegation in Drosophila: Towards a genetics of chromatin assembly

1989 • 134 citations

The Drosophila zeste protein binds cooperatively to sites in many gene regulatory regions: implications for transvection and gene regulation.

1988 • 120 citations

Mutations in polycombeotic, a Drosophila polycomb-group gene, cause a wide range of maternal and zygotic phenotypes.

1990 • 110 citations

Transactivation of the Xenopus rRNA gene promoter by its enhancer

1989 • 108 citations

Functional domains of SIR4, a gene required for position effect regulation in Saccharomyces cerevisiae.

1987 • 105 citations

Trans-inactivation of the Drosophila brown gene: evidence for transcriptional repression and somatic pairing dependence.

1989 • 99 citations

The anterobithorax and bithorax mutations of the bithorax complex.

1986 • 98 citations

INTERACTIONS OF ZESTE MUTATIONS WITH LOCI EXHIBITING TRANSVECTION EFFECTS IN DROSOPHILA MELANOGASTER

1982 • 92 citations

Contrabithorax mutations cause inappropriate expression of Ultrabithorax products in Drosophila

1985 • 86 citations

Homeosis and the interaction of zeste and white in Drosophila

1989 • 85 citations

The Drosophila zeste gene and transvection

1989 • 84 citations

Self-association of the Drosophila zeste protein is responsible for transvection effects.

1990 • 80 citations

Developmental expression of the Drosophila zeste gene and localization of zeste protein on polytene chromosomes.

1988 • 67 citations

The product of the Drosophila zeste gene binds to specific DNA sequences in white and Ubx.

1987 • 61 citations

Gene Activity dependent on Chromosome Synapsis in the Polytene Chromosomes of Drosophila melanogaster

1967 • 51 citations

The Drosophila zeste locus is nonessential.

1989 • 44 citations

Genetic analysis of the larval secretion gene Sgs-4 and its regulatory chromosome sites in Drosophila melanogaster

1981 • 43 citations

THE OCCURRENCE OF X-RAY INDUCED DOMINANT LETHAL MUTATIONS IN HABROBRACON

1945 • 34 citations

Materials for the Study of the Position Effect of Normal and Mutant Genes

1944 • 26 citations

Proximity-dependent enhancement of Sgs-4 gene expression in D. melanogaster

1986 • 20 citations