CD4+CD25+ Regulatory T Cells Inhibit Experimental Anti-Glomerular Basement Membrane Glomerulonephritis in Mice

Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells

2010 • 5,969 citations

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

2004 • 4,872 citations

Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor Foxp3

2003 • 4,529 citations

A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

1997 • 3,625 citations

N<scp>aturally</scp>A<scp>rising</scp>CD4⁺R<scp>egulatory</scp>T C<scp>ells for</scp>I<scp>mmunologic</scp>S<scp>elf</scp>-T<scp>olerance and</scp>N<scp>egative</scp>C<scp>ontrol of</scp>I<scp>mmune</scp>R<scp>esponses</scp>

2003 • 3,323 citations

CD4+CD25+ suppressor T cells: more questions than answers

2002 • 2,202 citations

Loss of Functional Suppression by CD4+CD25+ Regulatory T Cells in Patients with Multiple Sclerosis

2004 • 1,835 citations

Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

2001 • 1,659 citations

Cell Contact–Dependent Immunosuppression by Cd4+Cd25+Regulatory T Cells Is Mediated by Cell Surface–Bound Transforming Growth Factor β

2001 • 1,609 citations

Ex Vivo Isolation and Characterization of Cd4+Cd25+ T Cells with Regulatory Properties from Human Blood

2001 • 1,168 citations

Cutting Edge: Cure of Colitis by CD4+CD25+ Regulatory T Cells

2003 • 933 citations

CD4+CD25+ T Cells Inhibit Both the Induction and Effector Function of Autoreactive T Cells and Represent a Unique Lineage of Immunoregulatory Cells

1998 • 893 citations

Large-scale in vitro expansion of polyclonal human CD4+CD25high regulatory T cells

2004 • 505 citations

Human CD4+CD25+ thymocytes and peripheral T cells have immune suppressive activityin vitro

2001 • 498 citations

Defective Suppressor Function of Human CD4+ CD25+ Regulatory T Cells in Autoimmune Polyglandular Syndrome Type II

2004 • 359 citations

A mononuclear cell component in experimental immunological glomerulonephritis.

1978 • 317 citations

Regulatory T Cells in the Control of Autoimmunity: the Essential Role of Transforming Growth Factor β and Interleukin 4 in the Prevention of Autoimmune Thyroiditis in Rats by Peripheral CD4+CD45RC− Cells and CD4+CD8− Thymocytes

1999 • 269 citations

CD4+CD25+ regulatory T-cell deficiency in patients with hepatitis C-mixed cryoglobulinemia vasculitis

2003 • 221 citations

The Impact of T Helper and T Regulatory Cells on the Regulation of Anti-Double-Stranded DNA B Cells

2002 • 220 citations

Plasminogen and Plasminogen Activators Protect against Renal Injury in Crescentic Glomerulonephritis

1997 • 201 citations

Growth and expansion of human T regulatory type 1 cells are independent from TCR activation but require exogenous cytokines

2002 • 194 citations

Susceptibility to anti-glomerular basement membrane disease and Goodpasture syndrome is linked to MHC class II genes and the emergence of T cell-mediated immunity in mice.

1997 • 177 citations

Evidence for a pathogenic role of a cell-mediated immune mechanism in experimental glomerulonephritis.

1978 • 175 citations

Th2 cells are less susceptible than Th1 cells to the suppressive activity of CD25+ regulatory thymocytes because of their responsiveness to different cytokines

2003 • 172 citations

Th1 responsiveness to nephritogenic antigens determines susceptibility to crescentic glomerulonephritis in mice

1997 • 168 citations

A Comparative Study between T Regulatory Type 1 and CD4+CD25+ T Cells in the Control of Inflammation

2003 • 153 citations

CD4+CD25+ T Cells Lyse Antigen-Presenting B Cells by Fas-Fas Ligand Interaction in an Epitope-Specific Manner

2003 • 142 citations

Control of Immune Pathology by Regulatory T Cells

2003 • 136 citations

IFN-γ Mediates Crescent Formation and Cell-Mediated Immune Injury in Murine Glomerulonephritis

1999 • 134 citations

P-selectin deficiency exacerbates experimental glomerulonephritis: a protective role for endothelial P-selectin in inflammation

1999 • 124 citations

New avian model of experimental glomerulonephritis consistent with mediation by cellular immunity. Nonhumorally mediated glomerulonephritis in chickens.

1984 • 118 citations

Regulation by CD25+ lymphocytes of autoantigen-specific T-cell responses in Goodpasture's (anti-GBM) disease

2003 • 111 citations

Goodpasture Disease

1999 • 104 citations

CD4⁺T-Cell Subsets That Mediate Immunological Memory toMycobacterium tuberculosisInfection in Mice

2000 • 95 citations

Identification of a clinically relevant immunodominant region of collagen IV in Goodpasture disease

1999 • 89 citations

A cell-mediated reaction against glomerular-bound immune complexes.

1979 • 87 citations

IL-12 directs severe renal injury, crescent formation and Th1 responses in murine glomerulonephritis

1999 • 87 citations

Cell-mediated immune injury in the kidney: Acute nephritis induced in the rat by azobenzenearsonate

1994 • 78 citations

Murine interstitial nephritis. II. The adoptive transfer of disease with immune T lymphocytes produces a phenotypically complex interstitial lesion.

1984 • 67 citations

Major Histocompatibility Complex Class II Expression by Intrinsic Renal Cells Is Required for Crescentic Glomerulonephritis

1998 • 64 citations

Transfer of experimental glomerulonephritis in chickens by mononuclear cells

1988 • 63 citations

Increased expression of transforming growth factor-?? in renal disease

1994 • 47 citations

Regulatory interactions of αβ and γλ T cells in glomerulonephritis

2000 • 45 citations