A randomized, double‐blind comparison of two dosage levels of recombinant factor VIIa in the treatment of joint, muscle and mucocutaneous haemorrhages in persons with haemophilia A and B, with and without inhibitors

Incidence of development of factor VIII and factor IX inhibitors in haemophiliacs

1992 • 613 citations

Recombinant Factor VIII for the Treatment of Previously Untreated Patients with Hemophilia A -- Safety, Efficacy, and Development of Inhibitors

1993 • 482 citations

A multicenter study of recombinant factor VIII (recombinate): safety, efficacy, and inhibitor risk in previously untreated patients with hemophilia A. The Recombinate Study Group.

1994 • 352 citations

The Effect of Activated Prothrombin-Complex Concentrate (FEIBA) on Joint and Muscle Bleeding in Patients with Hemophilia A and Antibodies to Factor VIII

1981 • 303 citations

Human Recombinant DNA–Derived Antihemophilic Factor (Factor VIII) in the Treatment of Hemophilia A

1990 • 261 citations

Efficacy of Prothrombin-Complex Concentrates in Hemophiliacs with Antibodies to Factor VIII

1980 • 257 citations

Pharmacokinetics and pharmacodynamics of recombinant factor VIIa

1994 • 256 citations

Recombinant Factor VIII for the Treatment of Previously Untreated Patients with Hemophilia A

1993 • 183 citations

Frequency of inhibitor development in haemophiliacs treated with low-purity factor VIII

1993 • 164 citations

Factors IXa and Xa play distinct roles in tissue factor-dependent initiation of coagulation

1995 • 162 citations

Thrombogenicity associated with factor IX complex concentrates.

1991 • 154 citations

The Use of Porcine Factor VIII Concentrate (Hyate:C) in the Treatment of Patients With Inhibitor Antibodies to Factor VIII

1989 • 151 citations

Autoplex versus proplex: a controlled, double-blind study of effectiveness in acute hemarthroses in hemophiliacs with inhibitors to factor VIII

1983 • 125 citations

Major Surgery in Haemophilic Patients with Inhibitors Using Recombinant Factor VIla

1996 • 121 citations

Recombinant human extrinsic pathway inhibitor. Production, isolation, and characterization of its inhibitory activity on tissue factor-initiated coagulation reactions.

1990 • 114 citations

The effect of activated prothrombin-complex concentrate (FEIBA) on joint and muscle bleedings in patients with haemophilia A with an inhibitor to Factor VIII

1982 • 90 citations

Recombinant Activated Factor VII in the Treatment of Bleeding Episodes in Patients With Inherited and Acquired Bleeding Disorders

1993 • 90 citations

Acute myocardial infarction during treatment with an activated prothrombin complex concentrate in a patient with Factor VIII deficiency and a factor VIII inhibitor

1988 • 81 citations

Recombinant Factor VIla (NovoSeven®) in the Treatment of Internal Bleeding in Patients with Factor VIM and IX Inhibitors

1996 • 75 citations

The incidence of factor VIII inhibitors in patients with severe hemophilia A

1995 • 71 citations

Use of recombinant activated factor VII for treatment of a retropharyngeal hemorrhage in a hemophilic patient with a high titer inhibitor

1989 • 63 citations

NovoSeven® (Recombinant Factor VIla) in Central Nervous System Bleeds

1996 • 62 citations

Recombinant activated factor VII (rFVIIa) therapy for intracranial hemorrhage in hemophilia a patients with inhibitors

1994 • 55 citations

Adverse Effects of Treatment with Porcine Factor VIII

1991 • 51 citations

Management of Hemophilia Patients with Inhibitors

1992 • 39 citations

Successful Hemostasis During a Major Orthopedic Operation by Using Recombinant Activated Factor VII in a Patient With Severe Hemophilia A and a Potent Inhibitor

1994 • 25 citations

Porcine factor VIII: preparation and use in treatment of inhibitor patients.

1984 • 24 citations

PROLONGED RECOMBINANT ACTIVATED FACTOR VII (rFVIIa) TREATMENT FOR SEVERE BLEEDING IN A FACTOR‐IX‐DEFICIENT PATIENT WITH AN INHIBITOR

1991 • 20 citations

Activated recombinant factor VII in the treatment of retroperitoneal haemorrhage in a patient with factor VIII inhibitor.

1994 • 3 citations