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Synthesis and characterization of halogenated derivatives of the ionophore of 5-(methylamino)-2-[[3,9,11-trimethyl-8-[1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-4-benzoxazolecarboxylic acid: enhanced calcium ion transport specificity by the 4-bromo derivative

Data up to Jan 2025

Published1981
Citations48
References25

Total Citations Per Year

Abstract

References (25)

A23187: A Divalent Cation Ionophore

1972 • 1,182 citations

Relationships between calcium and cyclic nucleotides in cell activation.

1977 • 849 citations

Action of ionophore A23187 at the cellular level. Separation of effects at the plasma and mitochondrial membranes.

1976 • 225 citations

Use of ionophore A23187 to measure cytoplasmic Ca buffering and activation of the Ca pump by internal Ca

1976 • 214 citations

Structure of A23187, a divalent cation ionophore

1974 • 208 citations

Norepinephrine, vasopressin, glucagon, and A23187 induce efflux of calcium from an exchangeable pool in isolated rat hepatocytes

1978 • 186 citations

Ionophore A23187: the effect of proton concentration on complex formation with divalent and monovalent cations and the demonstration of potassium(1+) ion transport in mitochondria mediated by A23187

1976 • 163 citations

Evidence for mitochondrial localization of the hormone-responsive pool of Ca2+ in isolated hepatocytes.

1979 • 128 citations

Cation transport and specificity of ionomycin. Comparison with ionophore A23187 in rat liver mitochondria.

1980 • 112 citations

Intracellular divalent cation release in pancreatic acinar cells during stimulus-secretion coupling. I. Use of chlorotetracycline as fluorescent probe.

1978 • 108 citations

On the mechanism of A23187-induced potassium efflux in rat liver mitochondria.

1980 • 84 citations

Some effects of ionophore A23187 on energy utilization and the distribution of cations and anions in mitochondria

1976 • 68 citations

Crystal and molecular structure of the calcium ion complex of A23187

1976 • 67 citations

Ionophore A23187. Solution conformations of the calcium complex and free acid deduced from proton and carbon-13 nuclear magnetic resonance studies

1976 • 67 citations

Calcium redistribution in individual cells correlated with ionophore action on motility

1978 • 59 citations

Effects of calcium ionophores on the transport and distribution of calcium in isolated cells and in liver and kidney slices

1978 • 48 citations

Ionophore A23187 disrupts membrane structure by modifying protein–lipid interactions

1979 • 48 citations

Indicators of free magnesium in biological systems

1974 • 46 citations

A proposed numbering system for polyether antibiotics.

1976 • 43 citations

Chemical transformations of antibiotic X-537A and their effect on antibacterial activity

1973 • 38 citations

Solution conformation of the ionophore A23187 and its magnesium salt

1977 • 38 citations

Synthetic cation transport peptides: calcium transport across phospholipid membranes

1980 • 17 citations

Isosteric metal complexes of ionophore A23187

1979 • 16 citations

Transport of mono- and divalent cations across chloroplast membranes mediated by the ionophore A23187

1980 • 15 citations

Conditions limiting the use of ionophore A23187 as a probe of divalent cation involvement in biological reactions. Evidence from the slow fluorescence quenching of Type A spinach chloroplasts

1979 • 8 citations

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Synthesis and characterization of halogenated derivatives of the ionophore of… (1981) – Biochemistry | Metascience Observatory Explorer