Does pharmacological treatment affect the sensation of breathlessness in terminal cancer patients?

Psychophysical bases of perceived exertion

1982 • 15,133 citations

Evaluation of Clinical Methods for Rating Dyspnea

1988 • 1,594 citations

Measurement of feelings using visual analogue scales.

1969 • 1,362 citations

Significance of Respiratory Symptoms and the Diagnosis of Chronic Bronchitis in a Working Population

1959 • 923 citations

Dyspnoea, disability, and distance walked: comparison of estimates of exercise performance in respiratory disease.

1978 • 446 citations

Aminophylline Improves Diaphragmatic Contractility

1981 • 401 citations

Dyspnea in Terminally Ill Cancer Patients

1986 • 357 citations

Diminished Ventilatory Response to Hypoxia and Hypercapnia after Morphine in Normal Man

1975 • 345 citations

Regulation of Respiration

1977 • 299 citations

Stretch reflex and servo action in a variety of human muscles.

1976 • 297 citations

Effects of Theophylline on Diaphragmatic Strength and Fatigue in Patients with Chronic Obstructive Pulmonary Disease

1984 • 290 citations

Effect of Bilateral Carotid-Body Resection on Ventilatory Control at Rest and during Exercise in Man

1971 • 273 citations

Breathing: Hering-Breuer Centenary Symposium.

1971 • 269 citations

THE SENSATION OF BREATHLESSNESS

1963 • 251 citations

Effects of Dihydrocodeine, Alcohol, and Caffeine on Breathlessness and Exercise Tolerance in Patients with Chronic Obstructive Lung Disease and Normal Blood Gases

1981 • 231 citations

Measuring Symptoms in Terminal Cancer: Are Pain and Dyspnoea Controlled?

1989 • 225 citations

The Relationship Between Pulmonary Function and Dyspnea in Obstructive Lung Disease

1989 • 189 citations

Mechanism of relief of dyspnea after thoracocentesis in patients with large pleural effusions

1983 • 180 citations

Pulmonary Edema

1973 • 175 citations

THE PHYSICAL AND MENIAL DISTRESS OF THE DYING

1963 • 169 citations

Effects of Oral Morphine on Breathlessness and Exercise Tolerance in Patients with Chronic Obstructive Pulmonary Disease

1989 • 161 citations

Intercostal muscle spindle activity and its γ‐motor control

1963 • 156 citations

DISPROPORTIONATELY SEVERE BREATHLESSNESS IN CHRONIC BRONCHITIS

1969 • 145 citations

Supplemental oxygen and exercise ability in chronic obstructive airways disease.

1988 • 142 citations

Effects of aminophylline upon right and left ventricular performance in chronic obstructive pulmonary disease

1978 • 141 citations

Breathlessness during different forms of ventilatory stimulation: a study of mechanisms in normal subjects and respiratory patients

1985 • 138 citations

Sustained-release theophylline reduces dyspnea in nonreversible obstructive airway disease.

1985 • 137 citations

Endorphins and the Control of Breathing

1981 • 134 citations

Therapeutics in Terminal Cancer

1984 • 117 citations

Effect of low dose nebulised morphine on exercise endurance in patients with chronic lung disease.

1989 • 115 citations

Diazepam in the Treatment of Dyspnoea in the ‘Pink Puffer’ Syndrome

1980 • 101 citations

RELEASE OF PROSTACYCLIN IN VIVO AND ITS ROLE IN MAN

1983 • 96 citations

The effects of morphine on venous tone in patients with acute pulmonary edema.

1976 • 94 citations

Neuronal Basis for the Central Action Of Chlorpromazine

1966 • 80 citations

Long-term management of respiratory symptoms in advanced cancer

1990 • 77 citations

The effect of Airway Anaesthesia on the Control of Breathing and the Sensation of Breathlessness in Man

1985 • 76 citations

Dyspnea: Physiological and Pathophysiological Mechanisms

1988 • 76 citations

Effects of morphine on ventilatory response to exercise

1979 • 73 citations

Gate mechanism in breathlessness caused by chest wall vibration in humans

1984 • 70 citations

Lignocaine aerosol and persistent cough

1977 • 62 citations

Correlation of ventilatory responses to hypoxia and hypercapnia.

1973 • 60 citations

THORACIC RECEPTORS CONNECTED WITH SENSATION

1977 • 60 citations

Neuronal responses in sensorimotor cortex to ramp displacements and maintained positions imposed on hindlimb of the unanesthetized monkey

1981 • 58 citations

Effects of morphine on the peripheral vascular response to sympathetic stimulation

1972 • 50 citations

Dyspnea: Diagnosis and Management

1987 • 48 citations

Single-Patient Randomized Clinical Trial

1986 • 47 citations

Mechanisms of Dyspnea

1987 • 47 citations

Chlorpromazine‐a specific effect on breathlessness?

1985 • 46 citations

RESPIRATORY SENSATIONS IN MAN

1977 • 45 citations

Dyspnoea: assessment and pharmacological manipulation.

1988 • 41 citations

Ventilation and breathlessness on maximal exercise in patients with interstitial lung disease after local anaesthetic aerosol inhalation

1988 • 41 citations

Dyspnoea: assessment and pharmacological manipulation

1988 • 40 citations

Domiciliary terminal care.

1980 • 38 citations

Haemodynamic effects of intravenous morphine in patients with acute myocardial infarction complicated by severe left ventricular failure.

1980 • 37 citations

Effects of Small-Particle Aerosols of Local Anaesthetic on Dyspnoea in Patients with Respiratory Disease

1985 • 32 citations

Effects of codeine on the respiratory responses to exercise in healthy subjects.

1983 • 32 citations

The deep-breath-venoconstriction reflex.

1969 • 28 citations

Palliative Care: The Management of Far-Advanced Illness

1984 • 28 citations

Clinical Care of the Terminal Cancer Patient.

1983 • 25 citations

Diseases of the Organs of Respiration.

1902 • 25 citations

Predictors of hospice utilization patterns

1986 • 20 citations

Assessment of dyspnoea.

1988 • 19 citations

The chemical regulation of ventilation

1971 • 18 citations

An approach to dyspnea in cancer patients

1989 • 15 citations

[Diseases of the respiratory organs].

1959 • 14 citations

Domiciliary Terminal Care

1988 • 14 citations

The Use of Oral Diazepam in Patients with Obstructive Lung Disease and Hypercapnia

1975 • 14 citations

Assessment of dyspnoea

1988 • 11 citations

Effects of salbutamol, ipratropium bromide and disodium cromoglycate on breathlessness induced by exercise in normal subjects.

1981 • 10 citations

Indomethacin and Perception of Dyspnea in Chronic Airflow Obstruction

1988 • 10 citations

Clinical Problems of Ventilatory Control

1980 • 8 citations

A clinical data base for advanced cancer patients

1988 • 7 citations

Symptom Control in Palliative Home Care

1990 • 1 citations