Loss of heterozygosity of the oestrogen receptor gene in breast cancer

pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long‐term follow‐up

1991 • 5,979 citations

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase

1988 • 4,259 citations

Allelotype of breast cancer: cumulative allele losses promote tumor progression in primary breast cancer.

1990 • 511 citations

Genomic organization of the human oestrogen receptor gene.

1988 • 480 citations

Localization of the Estrogen Receptor Locus (ESR) to Chromosome 6q25.1 by FISH and a Simple Post-FISH Banding Technique

1993 • 229 citations

Accumulation of genetic alterations and progression of primary breast cancer.

1991 • 229 citations

Allelotype of human breast carcinoma: a second major site for loss of heterozygosity is on chromosome 6q.

1991 • 194 citations

Frequent loss of heterozygosity on chromosomes 6q, 11, and 17 in human ovarian carcinomas.

1990 • 189 citations

Loss of heterozygosity on chromosome 7q and aggressive primary breast cancer

1992 • 168 citations

Heterogeneity for Allelic Loss in Human Breast Cancer

1992 • 135 citations

Genetic alterations of the tumour suppressor gene regions 3p, 11p, 13q, 17p, and 17q in human breast carcinomas

1992 • 107 citations

Estrogen receptor variant messenger RNA lacking exon 4 in estrogen-responsive human breast cancer cell lines.

1993 • 93 citations

Dinucleotide repeat polymorphism in the human estrogen receptor (ESR) gene

1992 • 59 citations

Microsatellite polymorphisms and the genetic linkage map of the human genome

1993 • 51 citations

Estrogen and progesterone receptors: Correlation of response rates, site and timing of receptor analysis

1982 • 41 citations

Role of estrogen receptor variants in the development of hormone resistance in breast cancer

1992 • 39 citations

The ER-positive / PgR-negative breast cancer phenotype is not associated with mutations within the DNA binding domain

1993 • 38 citations

Estrogen receptors and response to endocrine therapy and cytotoxic chemotherapy in advanced breast cancer

1980 • 37 citations

Molecular lesions involved in the progression of a human breast cancer.

1988 • 32 citations

Chromosome anomalies in human breast cancer: evidence for specific involvement of 1q region in lymphocyte cultures.

1991 • 27 citations

Prognostic factors for recurrence and survival in axillary node-negative breast cancer

1989 • 25 citations

Loss of heterozygosity at selective sites on chromosomes 13 and 17 in human breast carcinoma.

1991 • 21 citations

Loss of heterozygosity at chromosome 17p is associated with HER‐2 amplification and lack of nodal involvement in breast cancer

1993 • 14 citations

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