Tyrosine Kinase-Independent Extracellular Action of Genistein on the CFTR Cl- Channel in Guinea Pig Ventricular Myocytes and CFTR-Transfected Mouse Fibroblasts.

Demonstration That CFTR Is a Chloride Channel by Alteration of Its Anion Selectivity

1991 • 1,108 citations

Cystic fibrosis: molecular biology and therapeutic implications

1992 • 820 citations

Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel

1991 • 658 citations

[41] Use of vanadate as protein-phosphotyrosine phosphatase inhibitor

1991 • 583 citations

Mode of regulation of the ACh-sensitive K-channel by the muscarinic receptor in rabbit atrial cells

1984 • 436 citations

[30] Use and specificity of genistein as inhibitor of protein-tyrosine kinases

1991 • 421 citations

cAMP-independent activation of CFTR Cl channels by the tyrosine kinase inhibitor genistein

1995 • 207 citations

Genistein potentiates wild-type and delta F508-CFTR channel activity

1997 • 205 citations

CFTR!

1992 • 192 citations

Actions of Genistein on Cystic Fibrosis Transmembrane Conductance Regulator Channel Gating

1998 • 162 citations

Modulation of CFTR chloride channels by calyculin A and genistein

1997 • 149 citations

Alternate stimulation of apical CFTR by genistein in epithelia

1996 • 146 citations

The CFTR Chloride Channel of Mammalian Heart

1995 • 140 citations

Direct action of genistein on CFTR

1997 • 139 citations

cAMP and genistein stimulate HCO3- conductance through CFTR in human airway epithelia

1997 • 128 citations

Genistein activates CFTR Cl- channels via a tyrosine kinase- and protein phosphatase-independent mechanism

1997 • 117 citations

Glibenclamide, an ATP-Sensitive K ⁺ Channel Blocker, Inhibits Cardiac cAMP-Activated Cl ⁻ Conductance

1995 • 95 citations

Inhibition of adenylate cyclase in human blood platelets by 9-substituted adenine derivatives.

1979 • 85 citations

Alternative splicing of CFTR Cl- channels in heart

1993 • 74 citations

CFTR chloride channel activation by genistein: the role of serine/threonine protein phosphatases

1996 • 69 citations

Genistein and tyrphostin 47 stimulate CFTR-mediated Cl- secretion in T84 cell monolayers

1995 • 69 citations

Cystic fibrosis gene encodes a cAMP-dependent chloride channel in heart.

1996 • 63 citations

Genistein Directly Inhibits L-Type Calcium Currents but Potentiates cAMP-Dependent Chloride Currents in Cardiomyocytes

1996 • 59 citations

Genistein Increases the Sensitivity of Cardiac Ion Channels to β-Adrenergic Receptor Stimulation

1998 • 48 citations

Activation of cardiac chloride conductance by the tyrosine kinase inhibitor, genistein

1996 • 38 citations

Tyrosine phosphorylation is a novel pathway for regulation of chloride secretion in shark rectal gland

1995 • 33 citations

Expression and regulation of chloride channels in neonatal rat cardiomyocytes

1996 • 26 citations

Synergistic activation of guinea‐pig cardiac cystic fibrosis transmembrane conductance regulator by the tyrosine kinase inhibitor genistein and cAMP

1997 • 22 citations

Phosphatase-Mediated Enhancement of Cardiac cAMP-Activated Cl ⁻ Conductance by a Cl ⁻ Channel Blocker, Anthracene-9-Carboxylate

1997 • 21 citations