Inhibition of human skin fibroblast collagenase, thermolysin, and Pseudomonas aeruginosa elastase by peptide hydroxamic acids

Structural basis of the action of thermolysin and related zinc peptidases

1988 • 675 citations

A linear equation that describes the steady-state kinetics of enzymes and subcellular particles interacting with tightly bound inhibitors

1972 • 524 citations

A continuous spectrophotometric assay for angiotensin converting enzyme

1979 • 416 citations

On the active site of proteases. III. Mapping the active site of papain; specific peptide inhibitors of papain

1968 • 400 citations

Effects of inhibitors of plasminogen activator, serine proteinases, and collagenase IV on the invasion of basement membranes by metastatic cells

1988 • 352 citations

[28] Assay of coagulation proteases using peptide chromogenic and fluorogenic substrates

1981 • 310 citations

The collagen substrate specificity of human neutrophil collagenase.

1987 • 285 citations

Binding of hydroxamic acid inhibitors to crystalline thermolysin suggests a pentacoordinate zinc intermediate in catalysis

1981 • 231 citations

Collagenase Inhibitors: Their Design and Potential Therapeutic Use

1987 • 121 citations

Purification of human collagenases with a hydroxamic acid affinity column

1986 • 114 citations

A new synthetic inhibitor of mammalian tissue collagenase inhibits bone resorption in culture

1985 • 98 citations

12-o-Tetradecanoyl-phorbol-13-acetate-differentiated U937 cells express a macrophage-like profile of neutral proteinases. High levels of secreted collagenase and collagenase inhibitor accompany low levels of intracellular elastase and cathepsin G.

1986 • 74 citations

Binding energetics of phosphorus-containing inhibitors of thermolysin

1989 • 56 citations

Phosphoramidate peptide inhibitors of human skin fibroblast collagenase

1990 • 40 citations

Kinetics of slow, tight-binding inhibitors of angiotensin converting enzyme

1986 • 13 citations

Latent collagenase of rheumatoid synovial fluid is not of granulocytic origin

1984 • 7 citations

Phthaloyl-Glycyl^P-Isoleucyl-Tryptophan Benzylamide is a Potent Inhibitor of Human Skin Fibroblast Collagenase with AK_iof 25nM

1989 • 7 citations