Light chain of tetanus toxin intracellularly inhibits acetylcholine release at neuro‐neuronal synapses, and its internalization is mediated by heavy chain

Molecular Pharmacology of Botulinum Toxin and Tetanus Toxin

1986 • 469 citations

Acceptors for botulinum neurotoxin reside on motor nerve terminals and mediate its internalization

1984 • 320 citations

Tetanus toxin: primary structure, expression in E. coli, and homology with botulinum toxins.

1986 • 307 citations

Clostridial Neurotoxins: Handling and Action at the Cellular and Molecular Level

1986 • 240 citations

Intracellularly injected tetanus toxin inhibits exocytosis in bovine adrenal chromaffin cells

1986 • 183 citations

The tetanus toxin light chain inhibits exocytosis

1989 • 129 citations

Tetanus toxin and botulinum A toxin inhibit release and uptake of various transmitters, as studied with particulate preparations from rat brain and spinal cord

1981 • 128 citations

Neurotransmitter release is blocked intracellularly by botulinum neurotoxin, and this requires uptake of both toxin polypeptides by a process mediated by the larger chain.

1988 • 120 citations

Transmission abolished on a cholinergic synapse after injection of acetylcholin-esterase into the presynaptic neurone

1974 • 100 citations

Distinct sites of action of clostridial neurotoxins revealed by double-poisoning of mouse motor nerve terminals

1987 • 95 citations

Selective location of acceptors for botulinum neurotoxin a in the central and peripheral nervous systems

1987 • 86 citations

Involvement of the constituent chains of botulinum neurotoxins A and B in the blockade of neurotransmitter release

1988 • 75 citations

Tetanus toxin: Biochemical and pharmacological comparison between its protoxin and some isotoxins obtained by limited proteolysis

1988 • 51 citations

Quantitative comparison between tetanus toxin, some fragments and toxoid for binding and axonal transport in the rat

1986 • 50 citations

Different effects of botulinum A toxin and tetanus toxin on the transmitter releasing process at the mammalian neuromuscular junction

1981 • 44 citations

Enzymatic breakdown of tetanus toxin

1974 • 40 citations

Tetanus Toxin and Botulinum A and C Neurotoxins Inhibit Noradrenaline Release from Cultured Mouse Brain

1988 • 38 citations

Fragment C of tetanus toxin antagonizes the neuromuscular blocking properties of native tetanus toxin.

1984 • 33 citations

Inhibition of transmitter release by botulinum neurotoxin A

1989 • 30 citations

Involvement of the constituent chains of botulinum neurotoxins A and B in the blockade of neurotransmitter release

1988 • 26 citations

Membrane properties of Aplysia neurones intracellularly injected with phospholipases A and C

1977 • 13 citations

On the transmitter at the A-to-B cell in Aplysia californica

1986 • 6 citations