Lith1, a major gene affecting cholesterol gallstone formation among inbred strains of mice.

MAPMAKER: An interactive computer package for constructing primary genetic linkage maps of experimental and natural populations

1987 • 6,762 citations

Mapping mendelian factors underlying quantitative traits using RFLP linkage maps.

1989 • 5,285 citations

Regulation of the mevalonate pathway

1990 • 5,282 citations

Critical tables for calculating the cholesterol saturation of native bile.

1978 • 788 citations

Gallbladder Disease in Pima Indians

1970 • 385 citations

Synthetic low and high fat diets for the study of atherosclerosis in the mouse.

1990 • 291 citations

Atherosclerosis susceptibility differences among progenitors of recombinant inbred strains of mice.

1990 • 281 citations

Pathogenesis of gallstones

1993 • 222 citations

Hepatic Cholesterol Metabolism in Patients with Gallstones

1975 • 168 citations

Effect of chenodeoxycholic acid and phenobarbital on the rate-limiting enzymes of hepatic cholesterol and bile acid synthesis in patients with gallstones.

1976 • 162 citations

Atherosclerosis and plasma and liver lipids in nine inbred strains of mice

1993 • 162 citations

Replacement of serine-871 of hamster 3-hydroxy-3-methylglutaryl-CoA reductase prevents phosphorylation by AMP-activated kinase and blocks inhibition of sterol synthesis induced by ATP depletion.

1993 • 161 citations

Induction of gallstones in mice by feeding a cholesterol-cholic acid containing diet

1964 • 142 citations

Serum lipids and gallstones: A case-control study

1990 • 139 citations

Hepatic mRNA levels for the LDL receptor and HMG-CoA reductase show coordinate regulation in vivo.

1992 • 120 citations

Bile acid synthesis in man: assay of hepatic microsomal cholesterol 7 alpha-hydroxylase activity by isotope dilution-mass spectrometry.

1986 • 102 citations

An Increased Familial Frequency of Gallstones

1983 • 102 citations

Effect of a dispersion of cholesterol in Triton WR-1339 on acyl CoA: Cholesterol acyltransferase in rat liver microsomes

1981 • 96 citations

Effect of dietary cholesterol and taurocholate on cholesterol 7 alpha-hydroxylase and hepatic LDL receptors in inbred mice

1993 • 84 citations

Effects of dietary cholesterol on cholesterol and bile acid homeostasis in patients with cholesterol gallstones.

1994 • 82 citations

Cholesterol gallstone formation. 2. Pathobiology and pathomechanics.

1992 • 77 citations

Hepatic HMGCoA reductase in human cholelithiasis: effects of chenodeoxycholic and ursodeoxycholic acids*

1980 • 76 citations

Genetics and epidemiology of gallbladder disease in New World native peoples.

1984 • 74 citations

Cholesterol and bile acids regulate cholesterol 7 alpha-hydroxylase expression at the transcriptional level in culture and in transgenic mice.

1994 • 72 citations

Cholesterol gallstone formation. 1. Physical-chemistry of bile and biliary lipid secretion.

1992 • 69 citations

Biliary lipid composition in monozygotic and dizygotic pairs of twins.

1989 • 55 citations

Function and Regulation of Hydroxylases Involved in the Bile Acid Biosynthesis Pathways

1992 • 55 citations

Biliary lipid synthesis and secretion in gallstone patients before and during treatment with chenodeoxycholic acid.

1980 • 48 citations

Genetic and dietary interactions in the regulation of HMG-CoA reductase gene expression.

1992 • 48 citations

Lithogenic bile in siblings of young women with cholelithiasis.

1972 • 47 citations

Familial Occurrence of Gallstone Disease

1973 • 43 citations

Modulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase by azole antimycotics requires lanosterol demethylation, but not 24,25-epoxylanosterol formation.

1987 • 42 citations

Bile salt hydrophobicity controls vesicle secretion rates and transformations in native bile

1992 • 42 citations

Different susceptibilities to the formation of cholesterol gallstones in mice

1987 • 32 citations

Somatic cell genetics and the study of cholesterol metabolism

1988 • 29 citations

HPLC analysis of desmosterol, 7‐dehydrocholesterol, and cholesterol

1989 • 29 citations

Effects of lovastatin and dietary cholesterol on bile acid kinetics and bile lipid composition in healthy male subjects.

1994 • 26 citations

Bile flow rate and cholesterol content in mice fed a gallstone-inducing diet

1964 • 25 citations

Inheritance of gall-bladder disease.

1959 • 24 citations

Strain difference in mouse cholelithiasis and the effect of taurine on the gallstone formation in mice

1978 • 22 citations

Cholesterol and Bile Acids Regulate Cholesterol 7 α-Hydroxylase Expression at the Transcriptional Level in Culture and in Transgenic Mice

1994 • 16 citations

Pathogenesis of gallstones.

1992 • 16 citations

Use of animal models for research in human nutrition

1990 • 6 citations