Convergent and divergent sequence evolution in the surface envelope glycoprotein of human immunodeficiency virus type 1 within a single infected patient.

The neighbor-joining method: a new method for reconstructing phylogenetic trees.

1987 • 59,130 citations

Coevolution of hosts and parasites

1982 • 1,623 citations

Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells.

1990 • 975 citations

Conserved Sequence and Structural Elements in the HIV-1 Principal Neutralizing Determinant

1990 • 665 citations

Temporal fluctuations in HIV quasispecies in vivo are not reflected by sequential HIV isolations

1989 • 655 citations

Principal neutralizing domain of the human immunodeficiency virus type 1 envelope protein.

1989 • 628 citations

Human immunodeficiency virus-infected individuals contain provirus in small numbers of peripheral mononuclear cells and at low copy numbers

1990 • 605 citations

Genetic Variation in HTLV-III/LAV Over Time in Patients with AIDS or at Risk for AIDS

1986 • 570 citations

Antigenic Diversity Thresholds and the Development of AIDS

1991 • 531 citations

Computer-assisted analysis of envelope protein sequences of seven human immunodeficiency virus isolates: prediction of antigenic epitopes in conserved and variable regions

1987 • 443 citations

Extensive variation of human immunodeficiency virus type-1 in vivo

1988 • 415 citations

Adaptive evolution in the stomach lysozymes of foregut fermenters

1987 • 376 citations

Analysis of sequence diversity in hypervariable regions of the external glycoprotein of human immunodeficiency virus type 1

1990 • 305 citations

Rates and dates of divergence between AIDS virus nucleotide sequences.

1988 • 259 citations

Concurrent evolution of human immunodeficiency virus type 1 in patients infected from the same source: rate of sequence change and low frequency of inactivating mutations

1990 • 222 citations

Characterization of HIV-1 neutralization escape mutants

1989 • 220 citations

HIV-1 V3 domain variation in brain and spleen of children with AIDS: Tissue-specific evolution within host-determined quasispecies

1991 • 209 citations

Discontinuous sequence change of human immunodeficiency virus (HIV) type 1 env sequences in plasma viral and lymphocyte-associated proviral populations in vivo: implications for models of HIV pathogenesis

1991 • 199 citations

The evolutionary dynamics of HIV-1 quasispecies and the development of immunodeficiency disease

1990 • 195 citations

Rapid emergence of novel antigenic and genetic variants of equine infectious anemia virus during persistent infection

1986 • 176 citations

Evolution of human immunodeficiency virus type 1 nef and long terminal repeat sequences over 4 years in vivo and in vitro

1991 • 144 citations

Evolution of sequences encoding the principal neutralization epitope of human immunodeficiency virus 1 is host dependent, rapid, and continuous.

1990 • 143 citations

Naturally occurring mutations within HIV-1 V3 genomic RNA lead to antigenic variation dependent on a single amino acid substitution

1991 • 140 citations

Antigenic variation in visna virus

1979 • 103 citations

Detection, quantification and sequencing of HIV-1 from the plasma of seropositive individuals and from factor VIII concentrates

1991 • 99 citations

Antigenic Variation in Lentiviral Diseases

1988 • 73 citations

Molecular evolution and phylogeny of the human AIDS viruses LAV, HTLV-III, and ARV

1987 • 65 citations

Evolution of the Structural Proteins of Human Immunodeficiency Virus: Selective Constraints on Nucleotide Substitution

1988 • 45 citations