Positioning of two alpha subunit carboxy-terminal domains of RNA polymerase at promoters by two transcription factors

Protein-protein communication within the transcription apparatus

1993 • 366 citations

Repressor structure and the mechanism of positive control

1983 • 324 citations

Domain organization of RNA polymerase α subunit: C-terminal 85 amino acids constitute a domain capable of dimerization and DNA binding

1994 • 237 citations

DNA-binding determinants of the alpha subunit of RNA polymerase: novel DNA-binding domain architecture.

1996 • 195 citations

Role of the RNA polymerase α subunit in transcription activation

1992 • 179 citations

Mutations that alter the ability of theEscherichia colicyclic AMP receptor protein to activate transcription

1990 • 174 citations

Solution Structure of the Activator Contact Domain of the RNA Polymerase α Subunit

1995 • 159 citations

The Escherichia coli RNA polymerase α subunit: structure and function

1995 • 152 citations

Identification of the activating region of catabolite gene activator protein (CAP): isolation and characterization of mutants of CAP specifically defective in transcription activation.

1993 • 146 citations

Helical phase dependent action of CRP: effect of the distance between the CRP site and the −35 region on promoter activity

1990 • 142 citations

Functional map of the alpha subunit of Escherichia coli RNA polymerase: two modes of transcription activation by positive factors.

1991 • 122 citations

Transcription factor recognition surface on the RNA polymerase alpha subunit is involved in contact with the DNA enhancer element.

1996 • 122 citations

Incorporation of an EDTA-metal complex at a rationally selected site within a protein: application to EDTA-iron DNA affinity cleaving with catabolite gene activator protein (CAP) and Cro

1992 • 109 citations

Characterization of the activating region of Escherichia coli catabolite gene activator protein (CAP) II. Role at class I and class II CAP-dependent promoters

1994 • 94 citations

Flexible linker in the RNA polymerase alpha subunit facilitates the independent motion of the C-terminal activator contact domain

1997 • 75 citations

Transcription Activation by the Escherichia coli Cyclic AMP

1994 • 66 citations

The two α subunits of Escherichia coli RNA polymerase are asymmetrically arranged and contact different halves of the DNA upstream element

1997 • 65 citations

Functional Map of the Alpha Subunit of RNA Polymerase: Insertion Analysis of the Amino-terminal Assembly Domain

1995 • 64 citations

Synthesis of the Protein Cutting Reagent Iron (S)-1-(p-Bromoacetamidobenzyl)ethylenediaminetetraacetate and Conjugation to Cysteine Side Chains

1997 • 63 citations

Functional Map of the Alpha Subunit of Escherichia coli RNA Polymerase

1994 • 50 citations

Structural Map of the Alpha Subunit of RNA Polymerase: Structural Domains Identified by Proteolytic Cleavage

1995 • 50 citations

Functional Map of the Alpha Subunit of RNA Polymerase: Amino Acid Substitution within the Amino-terminal Assembly Domain

1995 • 48 citations

[9] Reconstitution of RNA polymerase

1996 • 46 citations

Protein-protein interactions during transcription activation: the case of the Escherichia coli cyclic AMP receptor protein

1996 • 42 citations

Location of the C-Terminal Domain of the RNA Polymerase Subunit in Different Open Complexes at the Escherichia Coli Galactose Operon Regulatory Region

1996 • 41 citations

[24] Characterization of protein—DNA complexes by affinity cleaving

1991 • 40 citations

Subunit assembly in vivo of Escherichia coli RNA polymerase: role of the amino‐terminal assembly domain of alpha subunit

1996 • 21 citations