THE PURINE REQUIREMENT OF CELLS CULTURED FROM HUMANS AFFECTED WITH THE LESCH-NYHAN SYNDROME (HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE DEFICIENCY)
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References (18)
Amino Acid Metabolism in Mammalian Cell Cultures
1959 • 4,025 citations
Gene Action in the X-chromosome of the Mouse (Mus musculus L.)
1961 • 3,881 citations
Enzyme Defect Associated with a Sex-Linked Human Neurological Disorder and Excessive Purine Synthesis
1967 • 1,210 citations
An improved nutrient solution for diploid Chinese hamster and human cell lines
1963 • 890 citations
A specific enzyme defect in gout associated with overproduction of uric acid.
1967 • 477 citations
Biochemical Bases of Accelerated Purine Biosynthesis de Novo in Human Fibroblasts Lacking Hypoxanthine-Guanine Phosphoribosyltransferase
1968 • 251 citations
Mammalian X-Chromosome Action: Inactivation Limited in Spread and in Region of Origin
1963 • 247 citations
The Enzymology of Feedback Inhibition of Glutamine Phosphoribosylpyrophosphate Amidotransferase by Purine Ribonucleotides
1964 • 207 citations
X-Linked Hypoxanthine-Guanine Phosphoribosyl Transferase Deficiency: Heterozygote Has Two Clonal Populations
1968 • 195 citations
Single-allele expression at an X-linked hyperuricemia locus in heterozygous human cells.
1968 • 105 citations
On the Mechanism of Feedback Inhibition of Purine Biosynthesis de Novo in Ehrlich Ascites Tumor Cells in Vitro
1965 • 93 citations
Drug sensitivity as a genetic marker for human cell lines.
1962 • 56 citations
MEGALOBLASTIC ANÆMIA IN THE LESCH-NYHAN SYNDROME
1968 • 51 citations
UDP-glucose: ?-D-galactose-1-phosphate uridylyltransferase activity in cultured human fibroblasts
1967 • 42 citations
Clinical features of the Lesch-Nyhan syndrome. Introduction--clinical and genetic features.
1968 • 41 citations
The single-active-X: functional differentiation at the chromosome level.
1967 • 18 citations
A temperature-sensitive glucose-6-phosphate dehydrogenase in mutant cultured human cells.
1968 • 15 citations
Rational approaches to the treatment of the Lesch-Nyhan syndrome.
1968 • 2 citations