Increasing Power for Tests of Genetic Association in the Presence of Phenotype and/or Genotype Error by Use of Double-Sampling

Maximum Likelihood from Incomplete Data Via the EM Algorithm

1977 • 46,601 citations

Exploratory Data Analysis

1977 • 12,265 citations

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

1993 • 8,888 citations

A New Statistical Method for Haplotype Reconstruction from Population Data

2001 • 7,499 citations

Statistical Methods in Cancer Research

1980 • 6,825 citations

Merlin—rapid analysis of dense genetic maps using sparse gene flow trees

2001 • 3,369 citations

Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI.

1990 • 2,936 citations

Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population.

1995 • 1,977 citations

Inference of haplotypes from PCR-amplified samples of diploid populations.

1990 • 773 citations

Sensitivity of HER-2/neu antibodies in archival tissue samples: potential source of error in immunohistochemical studies of oncogene expression.

1994 • 495 citations

Errors of Measurement in Statistics

1968 • 473 citations

Accuracy of Haplotype Frequency Estimation for Biallelic Loci, via the Expectation-Maximization Algorithm for Unphased Diploid Genotype Data

2000 • 405 citations

The Advanced Theory of Statistics.

1947 • 387 citations

Detection and Integration of Genotyping Errors in Statistical Genetics

2002 • 359 citations

Assessing Allelic Dropout and Genotype Reliability Using Maximum Likelihood

2002 • 337 citations

Experimentally-derived haplotypes substantially increase the efficiency of linkage disequilibrium studies

2001 • 160 citations

Improved Method for Genotyping Apolipoprotein E Polymorphisms by a PCR-Based Assay Simultaneously Utilizing Two Distinct Restriction Enzymes

1997 • 158 citations

A General Approach to Analyzing Epidemiologic Data that Contain Misclassification Errors

1987 • 112 citations

An investigation of the effect of misclassification on the properties of x,2-tests in the analysis of categorical data

1965 • 101 citations

Case–Control Analysis with Partial Knowledge of Exposure Misclassification Probabilities

2001 • 97 citations

ERRORS AND LINKAGE DISEQUILIBRIUM INTERACT MULTIPLICATIVELY WHEN COMPUTING SAMPLE SIZES FOR GENETIC CASE-CONTROL ASSOCIATION STUDIES

2002 • 92 citations

On the Limiting Power Function of the Frequency Chi-Square Test

1958 • 89 citations

On the Use of Double Sampling Schemes in Analyzing Categorical Data with Misclassification Errors

1977 • 85 citations

What SNP genotyping errors are most costly for genetic association studies?

2004 • 84 citations

ASSESSMENT AND MANAGEMENT OF SINGLE NUCLEOTIDE POLYMORPHISM GENOTYPE ERRORS IN GENETIC ASSOCIATION ANALYSIS

2000 • 72 citations

Log-Linear Models for Categorical Data with Misclassification and Double Sampling

1979 • 69 citations

Error detection for genetic data, using likelihood methods.

1996 • 68 citations

Modulation byDLST of the genetic risk of Alzheimer's disease in a very elderly population

1999 • 39 citations

Genotyping Error Detection Through Tightly Linked Markers

2003 • 23 citations

Association of the dihydrolipoamide dehydrogenase gene with Alzheimer's disease in an Ashkenazi Jewish population

2004 • 18 citations

Substantial Linkage Disequilibrium Across the Dihydrolipoyl Succinyltransferase Gene Region Without Alzheimer's Disease Association

2004 • 7 citations

Neuropsychiatric Genetics: Misclassification in Linkage Studies of Phenotype-Genotype Research

2001 • 5 citations