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Impaired natural killer activity and expression of interleukin-2 receptor antigen in familial erythrophagocytic lymphohistiocytosis

Data up to Jan 2025

Published1990
Citations41
References27

Total Citations Per Year

Abstract

References (27)

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The p75 peptide is the receptor for interleukin 2 expressed on large granular lymphocytes and is responsible for the interleukin 2 activation of these cells.

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1983 • 129 citations

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1984 • 126 citations

Natural killer (HNK-1+) cells in Chediak-Higashi patients are present in normal numbers but are abnormal in function and morphology.

1982 • 99 citations

Interleukin 2 enhances the natural killer cell activity of acquired immunodeficiency syndrome patients through a gamma-interferon-independent mechanism.

1985 • 86 citations

Distribution of lymphocytes with interleukin-2 receptors (TAC antigens) in reactive lymphoproliferative processes, Hodgkin's disease, and non-Hodgkin's lymphomas. An immunohistologic study of 300 cases.

1987 • 85 citations

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1982 • 56 citations

Immunologic dysregulation in a patient with familial hemophagocytic lymphohistiocytosis

1987 • 39 citations

Natural killer‐interferon system in patients with preleukaemic states

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Peripheral blood lymphocytes from patients with cancer lack interleukin-2 receptors

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Familial erythrophagocytic lymphohistiocytosis: An association with serum lipid abnormalities

1983 • 28 citations

Mitogenicity and down-regulation of high-affinity interleukin 2 receptor by YTA-1 and YTA-2, monoclonal antibodies that recognize 75-kDa molecules on human large granular lymphocytes.

1989 • 26 citations

Use of VP-16–213 in the treatment of familial erythrophagocytic lymphohistiocytosis

1986 • 24 citations

Abnormalities of interleukin 2 receptor expression associated with decreased antigen-induced lymphocyte proliferation in patients with AIDS and related disorders.

1987 • 21 citations

Endoperoxidation, hyperprostaglandinemia, and hyperlipidemia in a case of erythrophagocytic lymphohistiocytosis. Reversal with VP-16 and indomethacin

1987 • 19 citations

Expression of CD 25 (Tac antigen) in lymphoid leukemias and non‐Hodgkin lymphomas

1987 • 13 citations

Reversible graft versus host reaction as cause of erythrophagic splenomegaly in a child?

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