Chromosomal Locations of Human Tissue Plasminogen Activator and Urokinase Genes

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Cloning and expression of human tissue-type plasminogen activator cDNA in E. coli

1983 • 1,241 citations

Changes in size and secondary structure of the ribosomal transcription unit during vertebrate evolution

1975 • 1,188 citations

Similar Amino Acid Sequences: Chance or Common Ancestry?

1981 • 855 citations

The role of gene dosage and genetic transpositions in carcinogenesis

1981 • 670 citations

Antibodies to plasminogen activator inhibit human tumor metastasis

1983 • 651 citations

Two human c-onc genes are located on the long arm of chromosome 8.

1982 • 329 citations

The Primary Structure of High Molecular Mass Urokinase from Human Urine. The Complete Amino Arid Sequence of the A Chain

1982 • 312 citations

The structure of the human tissue-type plasminogen activator gene: correlation of intron and exon structures to functional and structural domains.

1984 • 303 citations

The role of proteinase in cellular invasiveness

1983 • 297 citations

The Complete Amino Acid Sequence of Low Molecular Mass Urokinase from Human Urine

1982 • 230 citations

Identification and primary sequence of an unspliced human urokinase poly(A)+ RNA.

1984 • 229 citations

International System for Human Gene Nomenclature (1979) ISGN (1979)

1979 • 212 citations

Cancer biology: Heritable fragile sites in cancer

1984 • 210 citations

Evolution of Structure and Function of Proteases

1967 • 197 citations

Mapping the Human Genome, Cloned Genes, DNA Polymorphisms, and Inherited Disease

1982 • 197 citations

Tissue plasminogen activator: peptide analyses confirm an indirectly derived amino acid sequence, identify the active site serine residue, establish glycosylation sites, and localize variant differences

1984 • 176 citations

Human immune interferon gene is located on chromosome 12.

1983 • 173 citations

Current problems in mechanistic studies of serine and cysteine proteinases

1982 • 165 citations

The phylogeny of trypsin-related serine proteases and their zymogens. New methods for the investigation of distant evolutionary relationships

1975 • 152 citations

Interleukin 2 (IL2) is assigned to human chromosome 4

1984 • 143 citations

The secretion of plasminogen activators by human myeloid leukemic cells in vitro

1983 • 120 citations

Assignment of the β-glucuronidase structural gene to the pter→q22 region of chromosome 7 in man

1978 • 117 citations

The 1983 catalogue of mapped human genetic markers and report of the nomenclature committee

1984 • 66 citations

Tumor promoter PMA stimulates the synthesis and secretion of mouse pro-urokinase in MSV-transformed 3T3 cells: this is mediated by an increase in urokinase mRNA content.

1984 • 58 citations

Modulation of plasminogen activator in rodent mammary tumors by hormones and other effectors.

1983 • 57 citations

Effects of 12-O-Tetradecanoylphorbol 13-Acetate on the Production of mRNAs for Human Tissue-Type Plasminogen Activator

1983 • 53 citations

Modulation and mapping of a human plasminogen activator by cell fusion

1978 • 33 citations

The Human Gene Map 15 November 1983

1984 • 21 citations

The history of science today.

1986 • 2 citations