Heroin self-administration by rats: Influence of dose and physical dependence

Behavioral Analysis of Drug Dependence

1986 • 547 citations

Development of physical dependence on morphine in respect to time and dosage and quantification of the precipitated withdrawal syndrome in rats

1973 • 523 citations

Self Administration of and Behavioral Dependence on Drugs

1969 • 489 citations

Tolerance to and physical dependence on morphine in rats

1963 • 446 citations

Reinstatement of heroin and cocaine self-administration behavior in the rat by intracerebral application of morphine in the ventral tegmental area

1984 • 219 citations

Blockade of nucleus accumbens opiate receptors attenuates intravenous heroin reward in the rat

1985 • 175 citations

Quasi morphine-abstinence syndrome

1974 • 112 citations

Susceptibility to readdiction as a function of the addiction and withdrawal environments.

1965 • 99 citations

PRODUCTION OF TOLERANCE AND PHYSICAL DEPENDENCE IN THE RAT BY SIMPLE ADMINISTRATION OF MORPHINE IN DRINKING WATER

1982 • 91 citations

Ventral tegmental site of opiate reward: Antagonism by a hydrophilic opiate receptor blocker

1983 • 91 citations

Quantitative relationships among measures of morphine tolerance and physical dependence in the rat

1979 • 82 citations

Antagonist treatment in nucleus accumbers or periaqueductal grey affects heroin self-administration

1988 • 60 citations

Quantitative assessment of tolerance to and dependence on morphine in mice

1977 • 56 citations

Effects of single doses of N-Allylnormorphine on hindlimb reflexes of chronic spinal dogs during cycles of morphine addiction.

1953 • 52 citations

Behavioral and pharmacological aspects of opioid dependence: mixed agonist-antagonists.

1983 • 47 citations

Dose and physical dependence as factors in the self-administration of morphine by rats

1979 • 35 citations

Heroin self-administration: Effects of antagonist treatment in lateral hypothalamus

1987 • 31 citations

Effect of unit dose and route of administration on self-administration of morphine

1976 • 27 citations

Rapid induction of dependence to morphine in rats

1986 • 25 citations

Resumption of morphine self-administration by ex-addict rats: An attempt to modify tendencies to relapse.

1972 • 21 citations

Morphine preference in rats previously morphine dependent

1984 • 20 citations

Development of tolerance to the rewarding effects of self-administered S(+)-amphetamine

1980 • 19 citations

Production of physical dependence in rats by drinking a morphine solution

1986 • 17 citations