Effects of dietary purified eicosapentaenoic acid (20:5(n − 3)) and docosahexaenoic acid (22:6(n − 3)) on fatty acid desaturation and oxidation in isolated rat liver cells

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

1957 • 63,238 citations

The Rapid Preparation of Fatty Acid Esters for Gas Chromatographic Analysis

1961 • 1,842 citations

Cardiovascular Effects of n-3 Fatty Acids

1988 • 1,185 citations

Fish oils and plasma lipid and lipoprotein metabolism in humans: a critical review.

1989 • 1,152 citations

Preparation of rat liver cells

1973 • 1,137 citations

Dietary n-3 polyunsaturated fatty acids and amelioration of cardiovascular disease: possible mechanisms

1990 • 717 citations

Nutritional and hormonal factors influencing desaturation of essential fatty acids

1981 • 557 citations

Effect of Saturated and Unsaturated Fatty Acids on the Desaturation in Vitro of Palmitic, Stearic, Oleic, Linoleic, and Linolenic Acids

1966 • 406 citations

The adaptive effects of dietary fish and safflower oil on lipid and lipoprotein metabolism in perfused rat liver

1984 • 305 citations

Δ 6-desaturase activity in liver microsomes of rats fed diets enriched with cholesterol and/or ω3 fatty acids

1988 • 252 citations

Induction of peroxisomal β-oxidation in rat liver by high-fat diets

1980 • 215 citations

Regulation of the Activity of Acetyl Coenzyme A Carboxylase by Palmitoyl Coenzyme A and Citrate

1972 • 195 citations

Regulation of Fatty Acid Synthesis in Isolated Hepatocytes

1973 • 156 citations

Eicosapentaenoic acid inhibits synthesis and secretion of triacylglycerols by cultured rat hepatocytes

1986 • 140 citations

Effect of dietary fats on arachidonic acid and eicosapentaenoic acid biosynthesis and conversion to C22 fatty acids in isolated rat liver cells

1984 • 125 citations

Regulation of palmitate metabolism by carnitine and glucagon in hepatocytes isolated from fasted and carbohydrate refed rats

1977 • 121 citations

Effects of dietary fish oil on human mammary carcinoma and on lipid‐metabolizing enzymes

1989 • 116 citations

Dietary n-3 Polyunsaturated Fatty Acids: Modification of Rat Cardiac Lipids and Fatty Acid Composition

1986 • 115 citations

Interrelationship between the dietary regulation of fatty acid synthesis and the fatty acyl‐CoA desaturases

1977 • 113 citations

Effect of Dietary Cholesterol and/or ω3 Fatty Acids on Lipid Composition and Δ5-Desaturase Activity of Rat Liver Microsomes

1988 • 112 citations

Peroxisomal retroconversion of docosahexaenoic acid (22:6(n−3)) to eicosapentaenoic acid (20:5(n−3)) studied in isolated rat liver cells

1991 • 111 citations

Eicosapentaenoic acid inhibits cholesterol esterification in cultured parenchymal cells and isolated microsomes from rat liver.

1988 • 98 citations

Modification of fatty acid composition of membrane phospholipid in hepatocyte monolayer with n − 3, n − 6 and n − 9 fatty acids and its relationship to triacylglycerol production

1987 • 98 citations

Changes of arachidonic acid and n-3 polyunsaturated fatty acids of phospholipid classes in liver, plasma and platelets during dietary fat manipulation.

1984 • 77 citations

On the effect of peroxisomal β‐oxidation and carnitine palmitoyltransferase activity by eicosapentaenoic acid in liver and heart from rats

1990 • 74 citations

Comparative studies on composition of cardiac phospholipids in rats fed different vegetable oils

1980 • 71 citations

Effect of diet on linoleic acid desaturation and on some enzymes of carbohydrate metabolism

1970 • 71 citations

Identification of shellfish fatty acids and their effects on lipogenic enzymes

1980 • 70 citations

Changes of arachidonic acid and n − 3 polyunsaturated fatty acids of phospholipid classes in liver, plasma and platelets during dietary fat manipulation

1984 • 69 citations

Secretion of lecithin:cholesterol acyltransferase from isolated rat hepatocytes

1976 • 62 citations

linolenic acid desaturation and chain elongation and rapid turnover of phospholipid n − 3 fatty acids in isolated rat liver cells

1983 • 54 citations

The effect of feeding fish oils, vegetable oils and clofibrate on the ketogenesis from long chain fatty acids in hepatocytes

1986 • 42 citations

Effect of dietary fatty acid composition on the biosynthesis of unsaturated fatty acids in rat liver microsomes

1980 • 42 citations

The zellweger syndrome: Deficient conversion of docosahexaenoic acid (22:6(n−3)) to eicosapentaenoic acid (20:5(n−3)) and normal Δ4-desaturase activity in cultured skin fibroblasts

1990 • 37 citations

Metabolism of long-chain polyunsaturated fatty acids in isolated cardiac myocytes

1989 • 36 citations

Increased β-oxidation of erucic acid in perfused hearts from rats fed clofibrate

1980 • 33 citations

Studies on the regulation of arachidonic acid synthesis in isolated rat liver cells

1982 • 33 citations

Effect of polyunsaturated fatty acids on the desaturation in vitro of linoleic to γ-linolenic acid

1965 • 32 citations

The effect of clofibrate on heart and plasma lipids in rats fed a diet containing rapeseed oil

1979 • 20 citations

The metabolism of 20‐ and 22‐carbon unsaturated acids in rat heart and myocytes as mediated by feeding fish oil

1990 • 17 citations