IN VITRO ANALYSIS OF GADOLINIUM CHLORIDE ABROGATION OF THE SYSTEMIC TOLERANCE INDUCED BY PORTAL VENOUS ADMINISTRATION OF ULTRAVIOLET B-IRRADIATED DONOR CELLS1,2

A Theory of Self-Nonself Discrimination

1970 • 1,700 citations

Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis.

1981 • 1,281 citations

A NEW ANALYSIS OF ALLOGENEIC INTERACTIONS

1975 • 551 citations

Viral DNA in transformed cells

1974 • 429 citations

Molecular events in the induction of a nonresponsive state in interleukin 2-producing helper T-lymphocyte clones.

1987 • 310 citations

Hepatic Suppression of Sensitization to Antigen absorbed into the Portal System

1967 • 253 citations

An accessory cell-derived costimulatory signal acts independently of protein kinase C activation to allow T cell proliferation and prevent the induction of unresponsiveness.

1989 • 143 citations

Kupffer cell blockade inhibits induction of tolerance by the portal venous route.

1989 • 87 citations

KUPFFER CELL BLOCKADE INHIBITS INDUCTION OF TOLERANCE BY THE PORTAL VENOUS ROUTE

1989 • 85 citations

Studies on the induction of tolerance to alloantigens. I. The abrogation of potentials for delayed-type-hypersensitivity response to alloantigens by portal venous inoculation with allogeneic cells.

1985 • 85 citations

LYMPHOCYTE SUPPRESSION BY KUPFFER CELLS PREVENTS PORTAL VENOUS TOLERANCE INDUCTION

1993 • 72 citations

Kupffer cell blockade prevents induction of portal venous tolerance in rat cardiac allograft transplantation

1990 • 70 citations

Portal vein administration of donor cells promotes peripheral allospecific hyporesponsiveness and graft tolerance.

1994 • 61 citations

Pretransplant portal venous administration of donor antigen and portal venous allograft drainage synergistically prolong rat cardiac allograft survival.

1990 • 55 citations

Role of Kupffer Cells in the Induction of Tolerance after Liver Transplantation

1996 • 49 citations

Interactions between T lymphocyte subsets supported by interleukin 2-rich lymphokines produce acute rejection of vascularized cardiac allografts in T cell deprived rats.

1984 • 44 citations

ARGININE-SPECIFIC SUPPRESSION OF MIXED LYMPHOCYTE CULTURE REACTIVITY BY KUPFFER CELLS—A BASIS OF PORTAL VENOUS TOLERANCE

1991 • 41 citations

Induction of cytotoxic T cell precursors in vivo. Role of T helper cells.

1983 • 23 citations

Abrogation of the induction of portal venous tolerance in a cardiac transplant model resulting from Kupffer cell inhibition by gadolinium.

1990 • 23 citations

TOLERANCE INDUCTION OF ALLOREACTIVITY BY PORTAL VENOUS INOCULATION WITH ALLOGENEIC CELLS FOLLOWED BY THE INJECTION OF CYCLOPHOSPHAMIDE

1987 • 23 citations

ABROGATION OF THE INDUCTION OF PORTAL VENOUS TOLERANCE IN A CARDIAC TRANSPLANT MODEL RESULTING FROM KUPFFER CELL INHIBITION BY GADOLINIUM

1990 • 19 citations

Abrogation of the capacity of delayed-type hypersensitivity responses to alloantigens by intravenous injection of neuraminidase-treated allogeneic cells.

1987 • 15 citations

The anatomic site-specificity of tolerance induction to alloantigen.

1990 • 14 citations

Lanthanide "Blockade" of Antigen-Presenting Cells Suppresses Lymphocyte Proliferation by Inducing Nitric Oxide Synthesis

1993 • 13 citations

THE ANATOMIC SITE-SPECIFICITY OF TOLERANCE INDUCTION TO ALLOANTIGEN

1990 • 10 citations

DIFFERENTIAL EFFECTS OF PRETREATMENT WITH ULTRAVIOLET-B MODIFIED OR UNMODIFIED DONOR-SPECIFIC LEUKOCYTE TRANSFUSIONS ON INTESTINAL AND CARDIAC ALLOGRAFT SURVIVAL IN THE RAT

1992 • 5 citations