Expression of an Intestine-Specific Transcription Factor (CDX1) in Intestinal Metaplasia and in Subsequently Developed Intestinal Type of Cholangiocarcinoma in Rat Liver

Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

1981 • 14,396 citations

An Intestine-Specific Homeobox Gene Regulates Proliferation and Differentiation

1996 • 508 citations

Key Role of the Cdx2 Homeobox Gene in Extracellular Matrix–mediated Intestinal Cell Differentiation

1997 • 271 citations

CDX1 protein expression in normal, metaplastic, and neoplastic human alimentary tract epithelium

1997 • 214 citations

Molecular cloning, sequencing and expression of the mRNA encoding human Cdx1 and Cdx2 homeobox. Down-regulation of Cdx1 and Cdx2 mRNA expression during colorectal carcinogenesis

1997 • 206 citations

A mouse gene homologous to the Drosophila gene caudal is expressed in epithelial cells from the embryonic intestine.

1988 • 202 citations

Cdx-2 homeodomain protein expression in human and rat colorectal adenoma and carcinoma.

1995 • 158 citations

Metaplasia and precursor lesions of gallbladder carcinoma. Frequency, distribution, and probability of detection in routine histologic samples

1993 • 142 citations

Intestinal metaplasia as a common option of oval cells in relation to cholangiofibrosis in liver of rats exposed to 2-acetylaminofluorene.

1985 • 101 citations

Phenotypic characterization of metaplastic intestinal glands and ductular hepatocytes in cholangiofibrotic lesions rapidly induced in the caudate liver lobe of rats treated with furan.

1991 • 87 citations

Overexpression of C-NEU and C-MET during rat liver cholangiocarcinogenesis: A link between biliary intestinal metaplasia and mucin-producing cholangiocarcinoma

1999 • 83 citations

"Intestinal-type" of adenocarcinoma preferentially induced in right/caudate liver lobes of rats treated with furan.

1993 • 72 citations

Significance of intestinal metaplasia for the evolution of cancer in the biliary tract

1984 • 71 citations

Isolation, Characterization, and Precise Physical Localization of Human CDX1, a caudal-Type Homeobox Gene

1995 • 65 citations

Intestinal-Type Adenocarcinoma of the Gallbladder

1986 • 56 citations

Biliary Proliferation and Adaptation in Furan-Induced Rat Liver Injury and Carcinogenesis

1996 • 49 citations

Liver fluke-associated and sporadic cholangiocarcinoma: an immunohistochemical study of bile duct, peribiliary gland and tumour cell phenotypes

2006 • 47 citations

Mucosal Dysplasia of Gallbladder: Isolated and Adjacent Lesions to Carcinoma

1989 • 44 citations

Small cell carcinoma of the gall‐bladder with intestinal metaplastic epithelium

1998 • 42 citations

Histochemical and immunohistochemical studies on development of biliary carcinoma in forty-seven patients with choledochal cyst—Special reference to intestinal metaplasia in the biliary duct—

1985 • 41 citations

A unique rat model of bile ductular hyperplasia in which liver is almost totally replaced with well-differentiated bile ductules.

1994 • 38 citations

Carcinoma of the gallbladder: The correlation between histogenesis and prognosis

1989 • 36 citations

Sequential appearance of intestinal mucosal cell types in the right and caudate liver lobes of furan-treated rats

1992 • 35 citations

A new rat bile ductular epithelial cell culture model characterized by the appearance of polarized bile ductsin vitro

1997 • 34 citations

NEU overexpression in the furan rat model of cholangiocarcinogenesis compared with biliary ductal cell hyperplasia.

1997 • 32 citations

‘Metaplastic lesions’ in intrahepatic bile ducts in hepatolithiasis: A histochemical and immunohistochemical study

1990 • 29 citations

Intestinal metaplasia and altered enzyme expression in propylnitrosamine-induced Syrian hamster cholangiocellular and gallbladder lesions

1986 • 23 citations

Establishment of a novel rat cholangiocarcinoma cell culture model

1999 • 21 citations

Relation of histopathological features to prognosis of gallbladder cancer.

1990 • 19 citations

Cholangiocarcinomas induced by feeding 3'-methyl-4-dimethylaminoazobenzene to rats. Histopathology and ultrastructure.

1977 • 19 citations

A new rat bile ductular epithelial cell culture model characterized by the appearance of polarized bile ducts in vitro

1997 • 6 citations

A caudal-type homeobox gene activity associated with the development and regeneration of the liver.

1996 • 5 citations