Pharmacological heterogeneity of NMDA receptors in cerebellar granule cells in immature rat slices. A microfluorimetric study with the [Ca2+]i sensitive dye indo-1

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

Magnesium gates glutamate-activated channels in mouse central neurones

1984 • 3,999 citations

Developmental and regional expression in the rat brain and functional properties of four NMDA receptors

1994 • 3,437 citations

Glycine potentiates the NMDA response in cultured mouse brain neurons

1987 • 3,116 citations

Heteromeric NMDA Receptors: Molecular and Functional Distinction of Subtypes

1992 • 2,527 citations

The physiology of excitatory amino acids in the vertebrate central nervous system

1987 • 1,718 citations

Molecular diversity of the NMDA receptor channel

1992 • 1,354 citations

Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits.

1993 • 978 citations

Structure-activity relationships in the development of excitatory ammo acid receptor agonists and competitive antagonists

1990 • 905 citations

Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors.

1993 • 828 citations

Cooperative Modulation of [³H]MK‐801 Binding to the N‐Methyl‐d‐Aspartate Receptor‐Ion Channel Complex by l‐Glutamate, Glycine, and Polyamines

1988 • 755 citations

Developmental changes in distribution of NMDA receptor channel subunit mRNAs

1992 • 718 citations

Agonists and antagonists for excitatory amino acid receptors

1987 • 692 citations

7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex.

1988 • 517 citations

Non-competitive antagonists of excitatory amino acid receptors

1987 • 502 citations

The novel anticonvulsant MK‐801 binds to the activated state of the N‐methyl‐<scp>d</scp>‐aspartate receptor in rat brain

1987 • 452 citations

Developmental switch in the expression of NMDA receptors occurs in vivo and in vitro

1993 • 447 citations

NMDA-receptor channel diversity in the developing cerebellum

1994 • 325 citations

Modulation of excitatory amino acid receptors by group IIB metal cations in cultured mouse hippocampal neurones.

1989 • 275 citations

Ifenprodil and SL 82.0715 as cerebral anti-ischemic agents. I. Evidence for efficacy in models of focal cerebral ischemia.

1988 • 237 citations

Sensitivity of the N-methyl-D-aspartate receptor to polyamines is controlled by NR2 subunits.

1994 • 219 citations

Ifenprodil is a novel type of N-methyl-D-aspartate receptor antagonist: interaction with polyamines.

1989 • 215 citations

Ifenprodil and SL 82.0715 as cerebral anti-ischemic agents. II. Evidence for N-methyl-D-aspartate receptor antagonist properties.

1988 • 189 citations

The inhibition of single N‐methyl‐D‐aspartate‐activated channels by zinc ions on cultured rat neurones.

1990 • 170 citations

The developmental onset of NMDA receptor-channel activity during neuronal migration

1993 • 156 citations

Ifenprodil and SL 82.0715 as cerebral antiischemic agents. III. Evidence for antagonistic effects at the polyamine modulatory site within the N-methyl-D-aspartate receptor complex.

1990 • 154 citations

The pharmacotherapy of focal cortical ischaemia in the mouse

1990 • 151 citations

Ifenprodil blocks N-methyl-D-aspartate receptors by a two-component mechanism.

1991 • 127 citations

Differences in results from in vivo and in vitro studies on the use-dependency of N-methylaspartate antagonism by MK-801 and other phencyclidine receptor ligands

1988 • 99 citations

Is the discriminative stimulus produced by phencyclidine due to an interaction with N-methyl-d-aspartate receptors?

1988 • 78 citations

Ifenprodil prevents glutamate cytotoxicity via polyamine modulatory sites of N-methyl-D-aspartate receptors in cultured cortical neurons.

1993 • 64 citations

Neuroprotective effects of the N-methyl-D-aspartate receptor antagonists ifenprodil and SL-82,0715 on hippocampal cells in culture.

1992 • 60 citations

SL 82.0715, an NMDA antagonist acting at the polyamine site, does not induce neurotoxic effects on rat cortical neurons

1992 • 50 citations

The neuroprotective properties of ifenprodil, a novel NMDA receptor antagonist, in neuronal cell culture toxicity studies

1992 • 33 citations

Action of the anti-ischemic agent ifenprodil onN-methyl-d-aspartate and kainate-mediated excitotoxicity

1990 • 32 citations

Dihydropyridine- and omega-conotoxin-resistant, neomycin-sensitive calcium channels mediate the depolarization-induced increase in internal calcium levels in cortical slices from immature rat brain.

1992 • 31 citations

NMDA Receptors with Different Sensitivities to Magnesium and Ifenprodil Control the Release of [¹⁴C]Acetylcholine and [³H]Spermidine from Rat Striatal Slices in Vitro

1994 • 28 citations

Synergistic effects in the? 1- and? 1-adrenergic regulations of intracellular calcium levels in striatal astrocytes

1991 • 14 citations