Single‐step transformation of human breast epithelial cells by SV40 large T oncogene

Isolation and Characterization of a Spontaneously Immortalized Human Breast Epithelial Cell Line, MCF-10

1990 • 1,495 citations

Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin.

1990 • 994 citations

Oncogenes, antioncogenes, and the molecular bases of multistep carcinogenesis.

1989 • 961 citations

Induction of transformation and continuous cell lines from normal human mammary epithelial cells after exposure to benzo[a]pyrene.

1985 • 416 citations

Epithelial mouse mammary cell line exhibiting normal morphogenesis in vivo and functional differentiation in vitro.

1984 • 336 citations

Human papilloma virus DNAs immortalize normal human mammary epithelial cells and reduce their growth factor requirements.

1990 • 300 citations

A new diploid nontumorigenic human breast epithelial cell line isolated and propagated in chemically defined medium

1987 • 237 citations

Characterization of chromosomal anomalies in human breast cancer

1990 • 218 citations

SV40 T antigen alone drives karyotype instability that precedes neoplastic transformation of human diploid fibroblasts

1990 • 183 citations

In vitro transformation of human epithelial cells

1986 • 148 citations

Immortalization of Human Adult Normal Prostatic Epithelial Cells by Liposomes Containing Large T-SV40 Gene

1991 • 140 citations

A simplified method for passage and long-term growth of human mammary epithelial cells

1986 • 123 citations

The amplification unit on chromosome 11q13 in aggressive primary human breast tumors entails the bcl-1, int-2 and hst loci.

1989 • 114 citations

Transformation of human mammary epithelial cells by oncogenic retroviruses.

1988 • 103 citations

Epithelial HBL-100 cell line derived from milk of an apparently healthy woman harbours SV40 genetic information

1985 • 96 citations

Neoplastic transformation of mouse mammary epithelial cells by in vitro exposure to N-methyl-N-nitrosourea.

1988 • 40 citations

Characterization of normal breast epithelial cells in primary cultures: Differentiation and growth factor receptors studies

1992 • 29 citations

c-H-ras-1 expression in 7,12-dimethyl benzanthracene-induced Balb/c mouse mammary hyperplasias and their tumors.

1988 • 26 citations

Selective immortalization of a phenotypically distinct epithelial cell type by microinjection of SV40 DNA into cultured human milk cells

1990 • 24 citations

Loss of heterozygosity for the short arm of chromosome 11 (11p15) in human milk epithelial cells immortalized by microinjection of SV40 DNA.

1991 • 16 citations

Viral T-Antigen Interactions With Cellular Proto-oncogene and Anti-oncogene Products

1990 • 16 citations

Characterization and distribution in human tissues of a glycoproteic antigen defined by monoclonal antibody 1BE12 raised against the human breast cancer cell line T47D.

1990 • 13 citations

A novel monoclonal antibody (7B10) with differential reactivity between human mammary carcinoma and normal breast.

1987 • 11 citations

Two Monoclonal Antibodies Identify Antigens Preferentially Expressed on Normal Human Breast Cells Versus Breast Cancer Cells

1991 • 3 citations