Mechanism for the Increased Permeability in Endothelial Monolayers Induced by Elastase

A monoclonal antibody to the adherence-promoting leukocyte glycoprotein, CD18, reduces organ injury and improves survival from hemorrhagic shock and resuscitation in rabbits.

1988 • 434 citations

Tissue Destruction by Neutrophils

1989 • 389 citations

Degradation of fibronectin by human leukocyte elastase. Release of biologically active fragments.

1980 • 386 citations

ONO-5046, a novel inhibitor of human neutrophil elastase

1991 • 359 citations

Thrombin‐induced increase in albumin permeability across the endothelium

1986 • 307 citations

Leukocytes are required for increased lung microvascular permeability after microembolization in sheep.

1981 • 271 citations

Cationic Proteins of Human Granulocytes. II. Separation of the Cationic Proteins of the Granules of Leukemic Myeloid Cells

1974 • 243 citations

Endothelial cell killing by neutrophils. Synergistic interaction of oxygen products and proteases.

1989 • 199 citations

Physiology and Pathophysiology of Neutral Proteinases of Human Granulocytes

1984 • 134 citations

THE STICKING AND EMIGRATION OF WHITE BLOOD CELLS IN INFLAMMATION

1973 • 133 citations

A Rapid Procedure for the Large Scale Purification of Elastase and Cathepsin G from Human Sputum

1979 • 128 citations

Measurement of albumin permeability across endothelial monolayers in vitro

1987 • 114 citations

Pathology of the Adult Respiratory Distress Syndrome

1986 • 103 citations

Xanthine oxidase mediates elastase-induced injury to isolated lungs and endothelium

1987 • 87 citations

Anoxia-reoxygenation-induced, neutrophil-mediated endothelial cell injury: role of elastase

1990 • 80 citations

Molecular Basis of the Biological Function of Molybdenum

1974 • 71 citations

Neutrophil alveolitis following endotoxemia. Enhancement by previous exposure to hyperoxia.

1984 • 67 citations

Surface charge properties of the luminal front of blood vessel, walls: An electron microscopical analysis

1975 • 64 citations

Cationic neutrophil proteins increase transendothelial albumin movement

1987 • 59 citations

Polymorphonuclear leukocyte participation in acute oleic-acid-induced lung injury.

1983 • 57 citations

Influence of extracellular matrix in tumor necrosis factor-induced increase in endothelial permeability

1992 • 50 citations

INTERACTIONS BETWEEN GRANULOCYTE PROTEASES AND PROTEASE INHIBITORS IN THE LUNG

1981 • 15 citations

The Adult Respiratory Distress Syndrome: Cell Populations and Soluble Mediators in the Air Spaces of Patients at High Risk

1987 • 7 citations

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