A correlation between residual radiation-induced DNA double-strand breaks in cultured fibroblasts and late radiotherapy reactions in breast cancer patients

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1993 • 5,107 citations

Late effects toxicity scoring: the SOMA scale

1995 • 387 citations

Cellular basis of radiation-induced fibrosis

1995 • 371 citations

Prognostic factors for acute and late skin reactions in radiotheraphy patients

1996 • 306 citations

The christie hospital breast conservation trial: An update at 8 years from inception

1993 • 285 citations

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1982 • 275 citations

Evidence for individual differences in the radiosensitivity of human skin

1992 • 193 citations

Prospective comparison of in vitro normal cell radiosensitivity and normal tissue reactions in radiotherapy patients

1993 • 186 citations

Relationship between early and late normal-tissue injury after postmastectomy radiotherapy

1991 • 184 citations

Relationship between the in vitro radiosensitivity of skin fibroblasts and the expression of subcutaneous fibrosis, telangiectasia, and skin erythema after radiotherapy

1996 • 162 citations

Prediction of normal-tissue tolerance to radiotherapy from in-vitro cellular radiation sensitivity

1992 • 161 citations

Prognostic factors for breast recurrence after conservative breast surgery and radiotherapy: results from a randomised trial

1996 • 153 citations

Fibroblast radiosensitivity versus acute and late normal skin responses in patients treated for breast cancer

1995 • 137 citations

Evidence for a Positive Correlation betweenin VitroRadiosensitivity of Normal Human Skin Fibroblasts and the Occurrence of Subcutaneous Fibrosis after Radiotherapy

1994 • 125 citations

Conservation of the breast using two different radiotherapy techniques: Interim report of a clinical trial

1990 • 119 citations

The relationship between cellular radiation sensitivity and tissue response may provide the basis for individualising radiotherapy schedules

1994 • 113 citations

Clinical correlations between late normal tissue endpoints after radiotherapy: Implications for predictive assays of radiosensitivity

1993 • 111 citations

Fibroblasts from Ataxia Telangiectasia (AT) and AT Heterozygotes Show an Enhanced Level of Residual DNA Double-strand Breaks after Low Dose-rate γ-irradiation as Assayed by Pulsed Field Gel Electrophoresis

1991 • 106 citations

Induction and Rejoining of DNA Double-Strand Breaks and Interphase Chromosome Breaks after Exposure to X Rays in One Normal and Two Hypersensitive Human Fibroblast Cell Lines

1995 • 99 citations

Cellular radiosensitivity and dna damage in primary human fibroblasts

1994 • 84 citations

Radiosensitivity in Cultured Human Fibroblasts

1980 • 83 citations

Radiation-induced differentiation of human skin fibroblasts: relationship with cell survival and collagen production

1996 • 60 citations

SYBR Green I staining of pulsed field agarose gels is a sensitive and inexpensive way of quantitating DNA double-strand breaks in mammalian cells

1997 • 51 citations

Dosimetric evaluation of compensation in radiotherapy of the breast: MLC intensity modulation and physical compensators

1997 • 49 citations

The radiosensitivity of human fibroblast cell lines correlates with residual levels of DNA double-strand breaks

1998 • 46 citations

Tangential breast irradiation—rationale and methods for improving dosimetry

1994 • 42 citations

A correlation between residual DNA double-strand breaks and clonogenic measurements of radiosensitivity in fibroblasts from preradiotherapy cervix cancer patients

1997 • 37 citations

Lack of correlation between residual radiation-induced DNA damage, in keratinocytes assayed directly from skin, and late radiotherapy reactions in breast cancer patients

1999 • 16 citations

DNA double strand breaks in fibroblast cell lines, from non-Hodgkin's lymphoma patients, showing increased sensitivity to chronic gamma irradiation

1991 • 12 citations

Response to letter re: Prediction of normal tissue tolerance from in vitro cellular radiation sensitivity

1995 • 9 citations