ALLOZYMIC DIFFERENTIATION IN RESPONSE TO LABORATORY DEMOGRAPHIC SELECTION OFDROSOPHILA MELANOGASTER

Aging: A Theory Based on Free Radical and Radiation Chemistry

1956 • 8,252 citations

The moulding of senescence by natural selection

1966 • 2,252 citations

AN UNSOLVED PROBLEM OF BIOLOGY

1953 • 1,832 citations

Evolution in age-structured populations

1995 • 1,793 citations

Extension of Life-Span by Overexpression of Superoxide Dismutase and Catalase in Drosophila melanogaster

1994 • 1,461 citations

Genetic Data Analysis

1990 • 1,380 citations

Evolutionary biology of aging

1991 • 1,333 citations

Evolution in Age-Structured Populations

1981 • 949 citations

Evolution in Age-Structured Populations.

1995 • 803 citations

LABORATORY EVOLUTION OF POSTPONED SENESCENCE INDROSOPHILA MELANOGASTER

1984 • 774 citations

Laboratory Evolution of Postponed Senescence in Drosophila melanogaster

1984 • 641 citations

SELECTION FOR DELAYED SENESCENCE IN DROSOPHILA MELANOGASTER

1984 • 562 citations

Handbook of Detection of Enzymes on Electrophoretic Gels

2002 • 510 citations

GENETICS OF LIFE HISTORY IN DROSOPHILA MELANOGASTER. II. EXPLORATORY SELECTION EXPERIMENTS

1981 • 414 citations

Selection on stress resistance increases longevity in Drosophila melanogaster

1992 • 304 citations

Practical isozyme genetics

1988 • 300 citations

Evidence for positive selection in the superoxide dismutase (Sod) region of Drosophila melanogaster.

1994 • 290 citations

RESISTANCE TO ENVIRONMENTAL STRESS IN DROSOPHILA MELANOGASTER SELECTED FOR POSTPONED SENESCENCE

2004 • 270 citations

Old Age and Natural Death

2019 • 266 citations

Simultaneous Overexpression of Copper- and Zinc-containing Superoxide Dismutase and Catalase Retards Age-related Oxidative Damage and Increases Metabolic Potential in Drosophila melanogaster

1995 • 239 citations

Practical Isozyme Genetics

1989 • 239 citations

New paths in genetics

1942 • 201 citations

Life history evolution with antagonistic pleiotropy and overlapping generations

1985 • 170 citations

Overexpression of Cu-Zn superoxide dismutase in Drosophila does not affect life-span.

1990 • 162 citations

Genetic Effects on Aging

1990 • 147 citations

Eggs, enzymes, and evolution: natural genetic variants change insect fecundity.

1992 • 124 citations

Expression of Bovine Superoxide Dismutase in Drosophila melanogaster Augments Resistance to Oxidative Stress

1991 • 117 citations

Role of oxidative stress in Drosophila aging

1992 • 117 citations

THE EVOLUTION OF DEVELOPMENT INDROSOPHILA MELANOGASTERSELECTED FOR POSTPONED SENESCENCE

1994 • 115 citations

ADAPTATION AT SPECIFIC LOCI. IV. DIFFERENTIAL MATING SUCCESS AMONG GLYCOLYTIC ALLOZYME GENOTYPES OF COLIAS BUTTERFLIES

1985 • 109 citations

FURTHER GENETIC STUDIES OF THE SOUTH AMHERST POPULATION OF DROSOPHILA MELANOGASTER

1970 • 94 citations

CUMULATIVE PARENTAL AGE EFFECTS INDROSOPHILA SUBOBSCURA

1968 • 92 citations

Expression of bovine superoxide dismutase in Drosophila melanogaster augments resistance of oxidative stress.

1991 • 91 citations

MULTIGENIC RESPONSE TO ETHANOL IN DROSOPHILA MELANOGASTER

1981 • 84 citations

Allozymes in evolutionary genetics: self-imposed burden or extraordinary tool?

1994 • 75 citations

Physiological Significance of the Alcohol Dehydrogenase Polymorphism in Larvae of Drosophila

1987 • 70 citations

Quantitative genetics of postponed aging in Drosophila melanogaster. I. Analysis of outbred populations.

1991 • 65 citations

A qualitative analysis of some life-history correlates of longevity inDrosophila melanogaster

1988 • 63 citations

Localizing genes that defer senescence in Drosophila melanogaster

1988 • 62 citations

The effect of superoxide dismutase alleles on aging inDrosophila

1993 • 60 citations

Allozyme variation in the butterfly, Maniola jurtina (Lepidoptera: Satyrinae) (L.): evidence for selection

1993 • 54 citations

Parental age effects in Drosophila pseudoobscura

1968 • 51 citations

SELECTION FOR AMYLASE ALLOZYMES INDROSOPHILA MELANOGASTER

1977 • 46 citations

Phenotypic rescue by a bovine transgene in a Cu/Zn superoxide dismutase-null mutant of Drosophila melanogaster.

1994 • 40 citations

Chromosomal localization and regulation of the longevity determinant genes in a selected strain of Drosophila melanogaster

1993 • 40 citations

Genotype-by-environment and epistatic interactions in Drosophila melanogaster: the effects of Gpdh allozymes, genetic background and rearing temperature on larval developmental time and viability.

1989 • 36 citations

Selection affecting enzyme polymorphisms in laboratory populations of Drosophila melanogaster

1979 • 35 citations

THE RESPONSE OF ENZYME POLYMORPHISMS TO DEVELOPMENTAL RATE SELECTION IN DROSOPHILA MELANOGASTER

1983 • 33 citations

Superoxide dismutase in Drosophila melanogaster: biochemical and structural characterization of allozyme variants.

1981 • 33 citations

Two-dimensional protein electrophoretic analysis of postponed aging inDrosophila

1993 • 30 citations

DYNAMICS OF THE LINKAGE DISEQUILIBRIUM FUNCTION UNDER MODELS OF GENE-FREQUENCY HITCHHIKING

1981 • 29 citations

Genetic variation for superoxide dismutase level in Drosophila melanogaster

1986 • 29 citations

The epistasis ofAdhandGpdhallozymes and variation in the ethanol tolerance ofDrosophila melanogasterlarvae

1988 • 19 citations

Linkage disequilibrium in natural and experimental populations of Drosophila melanogaster.

1988 • 18 citations

The genetic basis of adaptation to selection for longevity inDrosophila melanogaster

1989 • 17 citations

Two modes of balancing selection in Drosophila melanogaster: overcompensation and overdominance.

1991 • 17 citations

Adaptive value of PGM polymorphism in laboratory populations ofDrosophila melanogaster

1980 • 15 citations

Longevity and Male Mating Success in Drosophila pseudoobscura

1981 • 11 citations

Allozyme polymorphism at the αGpdh and Adh loci and fitness in Drosophila melanogaster

1989 • 10 citations

THE EFFECT OF DDT ON THE POLYMORPHISM AT THE G6pd AND Pgd LOCI IN DROSOPHILA MELANOGASTER

1983 • 10 citations

The population genetics of alleles affecting enzyme activity

1992 • 9 citations

Electrophoretic variation at flight-related enzyme loci and its possible association with flight capacity inEpiphyas postvittana

1991 • 9 citations

Chromosome inversion polymorphisms inDrosophila melanogaster IV. Inversion and Adh allele frequency changes under selection for different development times

1987 • 7 citations