Expression of the tyrosine kinase c‐kit is an independent prognostic factor in patients with small cell lung cancer

Management of malignant gastrointestinal stromal tumours

2002 • 574 citations

Mutations in Exon 11 of c-Kit Occur Preferentially in Malignant versus Benign Gastrointestinal Stromal Tumors and Do Not Occur in Leiomyomas or Leiomyosarcomas

1999 • 555 citations

Biology and genetic aspects of gastrointestinal stromal tumors: KIT activation and cytogenetic alterations

2002 • 457 citations

Autocrine growth of small cell lung cancer mediated by coexpression of c-kit and stem cell factor.

1996 • 275 citations

The selective tyrosine kinase inhibitor STI571 inhibits small cell lung cancer growth.

2000 • 271 citations

Coexpression of the stem cell factor and the c-kit genes in small-cell lung cancer.

1991 • 258 citations

Growth inhibition and modulation of kinase pathways of small cell lung cancer cell lines by the novel tyrosine kinase inhibitor STI 571

2000 • 238 citations

The international system for staging lung cancer

2000 • 219 citations

Expression of c-kit receptor in normal and transformed human nonlymphoid tissues.

1992 • 208 citations

Preferential expression of c-kit protooncogene transcripts in small cell lung cancer

1992 • 182 citations

Expression of the proto-oncogenes c-met and c-kit and their ligands, hepatocyte growth factor/scatter factor and stem cell factor, in SCLC cell lines and xenografts

1993 • 164 citations

Characterization of c-kit expression in small cell lung cancer: prognostic and therapeutic implications.

2003 • 146 citations

Expression and prognostic significance of kit, protein kinase B, and mitogen-activated protein kinase in patients with small cell lung cancer.

2003 • 111 citations

Recombinant human stem cell factor mediates chemotaxis of small-cell lung cancer cell lines aberrantly expressing the c-kit protooncogene.

1993 • 95 citations

Analysis of c-kit protein expression in small-cell lung carcinoma and its implication for prognosis

2002 • 91 citations

Lack of c-kit exon 11 activating mutations in c-KIT/CD117-positive SCLC tumour specimens

2003 • 67 citations

CD117 (c-KIT) overexpression in patients with extensive-stage small-cell lung carcinoma

2003 • 56 citations

Ectopic expression of c-kit in small-cell lung cancer

1994 • 31 citations

Recombinant human stem cell factor does exert minor stimulation of growth in small cell lung cancer and melanoma cell lines

1995 • 30 citations

Specific Growth Inhibition of Small‐cell Lung Cancer Cells by Adenovirus Vector Expressing Antisense c‐kit Transcripts

1996 • 24 citations