Synovial lymphocytes and the aetiology of synovitis.

Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis.

1991 • 1,630 citations

Autoimmunity to type II collagen an experimental model of arthritis.

1977 • 1,599 citations

Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention

1988 • 940 citations

Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting

1991 • 892 citations

Human naive and memory T cells

1988 • 793 citations

Adhesion molecules controlling lymphocyte migration

1989 • 654 citations

Evidence for the Effects of a Superantigen in Rheumatoid Arthritis

1991 • 632 citations

Pathogenesis of lentivirus infections

1986 • 558 citations

Restricted use of T cell receptor V genes in murine autoimmune encephalomyelitis raises possibilities for antibody therapy

1988 • 555 citations

How important are t cells in chronic rheumatoid synovitis?

1990 • 553 citations

Genetic analysis of autoimmune type 1 diabetes mellitus in mice

1991 • 494 citations

CYCLOSPORIN INCREASES THE RATE AND LENGTH OF REMISSIONS IN INSULIN-DEPENDENT DIABETES OF RECENT ONSET

1986 • 443 citations

Limited heterogeneity of rearranged T-cell receptor Vα transcripts in brains of multiple sclerosis patients

1990 • 395 citations

Antigen recognition in autoimmune encephalomyelitis and the potential for peptide-mediated immunotherapy

1989 • 394 citations

Shared Human T Cell Receptor V _β Usage to Immunodominant Regions of Myelin Basic Protein

1990 • 386 citations

TNFα—A PIVOTAL ROLE IN RHEUMATOID ARTHRITIS?

1992 • 377 citations

Defining protective responses to pathogens: cytokine profiles in leprosy lesions

1991 • 375 citations

Prevention of type II collagen-induced arthritis by in vivo treatment with anti-L3T4.

1985 • 372 citations

Autoreactive T lymphocytes in multiple sclerosis determined by antigen-induced secretion of interferon-gamma.

1990 • 363 citations

Induction of Inflammatory Arthropathy Resembling Rheumatoid Arthritis in Mice Transgenic for HTLV-I

1991 • 344 citations

Type II collagen-induced arthritis in rats. Passive transfer with serum and evidence that IgG anticollagen antibodies can cause arthritis.

1982 • 339 citations

Limited T-cell receptor beta-chain heterogeneity among interleukin 2 receptor-positive synovial T cells suggests a role for superantigen in rheumatoid arthritis.

1991 • 297 citations

Arthritis induced in rats by cloned T lymphocytes responsive to mycobacteria but not to collagen type II.

1984 • 296 citations

Studies on the Specificity of the Cellular Infiltrate in Delayed Hypersensitivity Reactions

1963 • 294 citations

Clonal dominance among T-lymphocyte infiltrates in arthritis.

1988 • 268 citations

Transfer of diabetes in mice prevented by blockade of adhesion-promoting receptor on macrophages

1990 • 245 citations

The preferential accumulation of helper‐inducer T lymphocytes in inflammatory lesions: evidence for regulation by selective endothelial and homotypic adhesion

1988 • 230 citations

T cell recognition as the target for immune intervention in autoimmune disease

1989 • 218 citations

Angiogenesis inhibition suppresses collagen arthritis.

1992 • 188 citations

A mycobacterial 65-kD heat shock protein induces antigen-specific suppression of adjuvant arthritis, but is not itself arthritogenic.

1990 • 188 citations

Experimental allergic encephalomyelitis in the absence of a classical delayed-type hypersensitivity reaction. Severe paralytic disease correlates with the presence of interleukin 2 receptor-positive cells infiltrating the central nervous system.

1987 • 182 citations

Type 1 diabetes in mice is linked to the interleukin-1 receptor and Lsh/lty/Bcg genes on chromosome 1

1991 • 171 citations

T cell receptor V alpha-V beta repertoire and cytokine gene expression in active multiple sclerosis lesions.

1992 • 163 citations

Preferential V beta gene usage and lack of junctional sequence conservation among human T cell receptors specific for a tetanus toxin-derived peptide: evidence for a dominant role of a germline-encoded V region in antigen/major histocompatibility complex recognition.

1992 • 150 citations

T lymphocyte lines producing or vaccinating against autoimmune encephalomyelitis (EAE). Functional activation induces peanut agglutinin receptors and accumulation in the brain and thymus of line cells

1983 • 145 citations

The severe combined immunodeficiency (scid) mouse. A laboratory model for the analysis of Lyme arthritis and carditis.

1989 • 142 citations

Autoimmune reactions to heat‐shock proteins in pristane‐induced arthritis

1990 • 140 citations

Analysis of naturally occurring delayed-type hypersensitivity reactions in leprosy by in situ hybridization.

1989 • 103 citations

Therapy against murine collagen‐induced arthritis with T cell receptor V_β‐specific antibodies

1991 • 102 citations

Selective migration of the human helper‐inducer memory T cell subset: confirmation by in vivo cellular kinetic studies

1991 • 98 citations

Proteoglycan‐induced polyarthritis and spondylitis adoptively transferred to naive (nonimmunized) BALB/c mice

1990 • 90 citations

Limiting dilution analysis of the frequency of antigen-reactive lymphocytes isolated from the central nervous system of Lewis rats with experimental allergic encephalomyelitis

1987 • 64 citations

Enumeration of lymphokine mRNA-containing cells in vivo in a murine graft-versus-host reaction using the PCR.

1992 • 59 citations

Streptococcal cell wall arthritis. Passive transfer of disease with a T cell line and crossreactivity of streptococcal cell wall antigens with Mycobacterium tuberculosis.

1989 • 59 citations

The immunopathogenesis of rheumatoid arthritis

1991 • 58 citations

T‐Cell Recognition of Bacterial Heat‐Shock Proteins in Inflammatory Arthritis

1991 • 57 citations

Depletion of alpha/beta T cells by a monoclonal antibody against the alpha/beta T cell receptor suppresses established adjuvant arthritis, but not established collagen-induced arthritis in rats.

1992 • 54 citations

Diversity of rheumatoid synovial tissue T cells by T cell receptor analysis. Oligoclonal expansion in interleukin‐2–responsive cells

1991 • 47 citations

Lack of T cell oligoclonality in enzyme-digested synovial tissue and in synovial fluid in most patients with rheumatoid arthritis

1991 • 39 citations

Dissection of the mechanisms of immune injury in rheumatoid arthritis, using total lymphoid irradiation

1988 • 33 citations

Studies on the homing of Mycobacterium-sensitized T lymphocytes to the synovium during passive adjuvant arthritis

1990 • 17 citations

Intraocular trafficking of lymphocytes in locally induced experimental autoimmune uveoretinitis (EAU)

1988 • 16 citations

Arthritis by autoreactive T cell lines obtained from rats after injection of intestinal bacterial cell wall fragments

1992 • 14 citations