FIFTH GADDUM MEMORIAL LECTURE, UNIVERSITY OF BRISTOL, SEPTEMBER 1974

Nerve, Muscle and Synapse

1966 • 1,431 citations

The Physiology of Synapses

1964 • 1,239 citations

Muscarinic Cholinergic Binding in Rat Brain

1974 • 1,214 citations

THE EXCITATION AND DEPRESSION OF SPINAL NEURONES BY STRUCTURALLY RELATED AMINO ACIDS

1960 • 853 citations

Drugs, Neurotransmitters, and Schizophrenia

1974 • 832 citations

Iontophoretic studies of neurones in the mammalian cerebral cortex

1963 • 659 citations

THE UPTAKE OF [³H]GABA BY SLICES OF RAT CEREBRAL CORTEX

1968 • 543 citations

A pharmacological study of the depression of spinal neurones by glycine and related amino acids

1968 • 505 citations

The hyperpolarization of spinal motoneurones by glycine and related amino acids

1968 • 481 citations

High affinity uptake systems for glycine, glutamic and aspartic acids in synaptosomes of rat central nervous tissues

1972 • 476 citations

Properties of Opiate-Receptor Binding in Rat Brain

1973 • 437 citations

GABA UPTAKE IN RAT CENTRAL NERVOUS SYSTEM: COMPARISON OF UPTAKE IN SLICES AND HOMOGENATES AND THE EFFECTS OF SOME INHIBITORS

1971 • 417 citations

A study of the action of picrotoxin on the inhibitory neuromuscular junction of the crayfish

1969 • 414 citations

Inhibitory of glycine on spinal neurons in the cat.

1968 • 411 citations

Biochemical-physiology correlations in studies of the γ-aminobutyric acid system

1968 • 408 citations

Strychnine Binding Associated with Glycine Receptors of the Central Nervous System

1973 • 388 citations

A review — critical for idenctification of a central nervous system transmitter

1966 • 379 citations

Studies of the uptake of3H-GABA and [3H]glycine in slices and homogenates of rat brain and spinal cord by electron microscopic autoradiography

1972 • 371 citations

The specificity of strychnine as a glycine antagonist in the mammalian spinal cord

1971 • 353 citations

Pharmacology of Benzodiazepines: Laboratory and Clinical Correlations

1967 • 265 citations

Perspectives in Neuropharmacology

1973 • 261 citations

AMINO ACIDS AS CENTRAL NERVOUS TRANSMITTERS: THE INFLUENCE OF IONS, AMINO ACID ANALOGUES, AND ONTOGENY ON TRANSPORT SYSTEMS for <scp>l</scp>‐GLUTAMIC AND <scp>l</scp>‐ASPARTIC ACIDS AND GLYCINE INTO CENTRAL NERVOUS SYNAPTOSOMES OF THE RAT¹

1973 • 261 citations

Regulation of monoamine metabolism in the central nervous system.

1972 • 241 citations

Muscarinic cholinergic receptor binding: regional distribution in monkey brain

1974 • 236 citations

An investigation of primary or direct inhibition

1953 • 222 citations

The effects of substance P and other peptides on spinal neurons of the frog

1974 • 207 citations

Pharmacology of cortical inhibition

1966 • 182 citations

Strychnine Binding in Rat Spinal Cord Membranes Associated with the Synaptic Glycine Receptor: Cooperativity of Glycine Interactions

1974 • 165 citations

On the excitability and cooperativity of the electroplax membrane.

1968 • 159 citations

Biophysics of Junctional Transmission

1954 • 158 citations

Potassium-induced release of amino acids from cerebral cortex and spinal cord slices of the rat

1974 • 156 citations

A comparison of the concentration of glycine, a transmitter suspect, in different areas of the brain and spinal cord in seven different vertebrates

1969 • 151 citations

Amino Acid Neurotransmitter Candidates: Sodium-Dependent High-Affinity Uptake by Unique Synaptosomal Fractions

1972 • 144 citations

The Glycine Synaptic Receptor: Evidence That Strychnine Binding Is Associated with the Ionic Conductance Mechanism

1974 • 136 citations

Interaction of Benzodiazepines with Central Nervous Glycine Receptors: Possible Mechanism of Action

1974 • 136 citations

Opiate receptor binding: effects of enzymatic treatments.

1974 • 135 citations

Acetylcholine Receptor and Ion Conductance Modulator Sites at the Murine Neuromuscular Junction: Evidence from Specific Toxin Reactions

1973 • 133 citations

Metabolic response of synaptosomes to electrical stimulation: Release of amino acids

1970 • 131 citations

Substance P excitation of cerebral cortical Betz cells

1974 • 125 citations

Effect of electrical stimulation and high potassium concentrations on the efflux of [¹⁴C] glycine from slices of spinal cord

1971 • 119 citations

Further study on anion permeability of inhibitory post‐synaptic membrane of cat motoneurones

1962 • 116 citations

THE PROPERTIES OF MUSCARINIC RECEPTORS IN MAMMALIAN CEREBRAL CORTEX

1974 • 113 citations

Synaptic biochemistry of amino acids.

1973 • 109 citations

Efflux of amino acid neurotransmitters from rat spinal cord slices. II. Factors influencing the electrically induced efflux of [14Cglycine and3H-GABA

1971 • 105 citations

Neuropharmacology of the Affective Disorders

1973 • 104 citations

The effects of strychnine on the inhibition of interneurons by glycine and γ-aminobutyric acid

1969 • 94 citations

Isolation of Acetylcholine Receptors

1972 • 93 citations

Release of Neurotransmitters and Their Interaction with Receptors

1972 • 91 citations

Neurochemistry of cholinergic receptors

1974 • 85 citations

THE RELEASE OF AMINO ACIDS FROM THE HEMISECTED SPINAL CORD DURING STIMULATION

1972 • 80 citations

Strychnine and Cortical Inhibition

1967 • 78 citations

The action of glycine on cortical neurones

1969 • 77 citations

LSD and CNS Transmission

1972 • 71 citations

The Use of Autoradiographic Techniques for the Identification and Mapping of Transmitter-Specific Neurones in CNS

1973 • 71 citations

SYNAPTIC TRANSMISSION

1970 • 70 citations

An analysis of the action of strychnine on the recurrent IPSP and amino acid induced inhibitions in the cat spinal cord

1969 • 69 citations

Werman R:The cooperativity of -aminobutyric action on the membrane of locust muscle fibers.

1973 • 65 citations

Studies on uptake of intraventricularly administered tritiated noradrenaline and 5-hydroxytryptamine with combined fluorescence histochemical and autoradiographic techniques

1968 • 64 citations

Strychnine-sensitive inhibition in the medullary reticular formation: Evidence for glycine as an inhibitory transmitter

1972 • 57 citations

Analysis of glycine actions on spinal interneurones by intracellular recording

1968 • 56 citations

Specific Glycine-Accumulating Synaptosomes in the Spinal Cord of Rats

1972 • 46 citations

The distribution of glycine, a neurotransmitter suspect in the central nervous system of several vertebrate species*1

1968 • 45 citations

Selective Accumulation of 3H-Serotonin by Nerve Terminals of Raphe Neurones: An Autoradiographic Study

1973 • 42 citations

Dexetimide, a useful tool in acetylcholine-receptor localization

1973 • 41 citations

Observations on strychnine reversal

1911 • 37 citations

Electron microscopic identification of monoamine nerve ending particles in rat brain homogenates

1970 • 37 citations

Amino acids as central neurotransmitters.

1972 • 27 citations