Phosphate excess and progressive renal failure: The precipitation-calcification hypothesis

Hyperfiltration in remnant nephrons: a potentially adverse response to renal ablation

1981 • 1,664 citations

Control of glomerular hypertension limits glomerular injury in rats with reduced renal mass.

1985 • 931 citations

Nephron adaptation to renal injury or ablation

1985 • 633 citations

Hemodynamically mediated glomerular injury and the progressive nature of kidney disease

1983 • 607 citations

PROSPECTIVE RANDOMISED TRIAL OF EARLY DIETARY PROTEIN RESTRICTION IN CHRONIC RENAL FAILURE

1984 • 546 citations

On the pathogenesis of hyperparathyroidism in chronic experimental renal insufficiency in the dog

1971 • 484 citations

Renal functional reserve in humans

1983 • 479 citations

Calcium Carbonate as a Phosphate Binder in Patients with Chronic Renal Failure Undergoing Dialysis

1986 • 389 citations

Effect of dietary phosphorus on circulating concentrations of 1,25-dihydroxyvitamin D and immunoreactive parathyroid hormone in children with moderate renal insufficiency.

1984 • 360 citations

Chronic effects of dietary protein in the rat with intact and reduced renal mass

1986 • 337 citations

Preservation of Function in Experimental Renal Disease by Dietary Restriction of Phosphate

1978 • 296 citations

Inorganic Phosphate Treatment of Hypercalcemia of Diverse Etiologies

1966 • 243 citations

Reduction of dietary phosphorus absorption by phosphorus binders. A theoretical, in vitro, and in vivo study.

1989 • 241 citations

Effects of dietary protein and phosphorus restriction on the progression of early renal failure

1982 • 232 citations

The Effect of a Keto Acid–Amino Acid Supplement to a Restricted Diet on the Progression of Chronic Renal Failure

1984 • 207 citations

Renal toxicity of phosphate in rats

1980 • 191 citations

The absorption of dietary phosphorus and calcium in hemodialysis patients

1986 • 174 citations

Renal autoregulation and vulnerability to hypertensive injury in remnant kidney

1987 • 171 citations

Verapamil protects against progression of experimental chronic renal failure

1987 • 153 citations

Effect of various protein diets on growth, renal function, and survival of uremic rats

1979 • 150 citations

Role of dietary factors in the progression of chronic renal disease

1983 • 145 citations

Regulation of canine renal vesicle Pi transport by growth hormone and parathyroid hormone

1980 • 140 citations

Phosphate depletion arrests progression of chronic renal failure independent of protein intake

1986 • 138 citations

Mechanisms underlying transition from acute glomerular injury to late glomerular sclerosis in a rat model of nephrotic syndrome.

1988 • 130 citations

Precipitous Fall in Serum Calcium, Hypotension, and Acute Renal Failure After Intravenous Phosphate Therapy for Hypercalcemia

1967 • 124 citations

THE EFFECT OF DIETARY PROTEIN ON THE COURSE OF NEPHROTOXIC NEPHRITIS IN RATS

1939 • 121 citations

RENAL DAMAGE FOLLOWING THE INGESTION OF A DIET CONTAINING AN EXCESS OF INORGANIC PHOSPHATE

1935 • 120 citations

Selective effect of low protein diets in chronic renal diseases.

1984 • 117 citations

Dietary restrictions early and late: effects on the nephropathy of the NZB X NZW mouse.

1978 • 112 citations

Effects on Renal Function of a Low-Nitrogen Diet Supplemented with Essential Amino Acids and Ketoanalogues and of Hemodialysis and Free Protein Supply in Patients with Chronic Renal Failure

1981 • 112 citations

Preservation of renal function in experimental glomerulonephritis

1980 • 111 citations

Serial micropuncture analysis of single nephron function in subtotal renal ablation

1988 • 105 citations

Effects of parathyroid hormone on cytosolic calcium in renal proximal tubular primary cultures

1986 • 105 citations

Effects of nephron reduction and dietary protein content on renal ammoniagenesis in the rat

1975 • 99 citations

Progression of renal failure in patients with renal disease of diverse etiology on protein-restricted diet

1985 • 98 citations

Micropuncture study of water and electrolyte movements along the loop of henle in Psammomys with special reference to magnesium, calcium and phosphorus

1973 • 92 citations

Parathyroid hormone and 1,25(OH)2D3 in chronic renal failure

1988 • 90 citations

The decline of renal function slowed by very low phosphorus intake in chronic renal patients following a low nitrogen diet.

1984 • 88 citations

Long-term renal responses to high dietary protein in dogs with 75% nephrectomy

1986 • 88 citations

The Use of Magnesium-Containing Phosphate Binders in Patients with End-Stage Renal Disease on Maintenance Hemodialysis

1982 • 86 citations

1,25-dihydroxycholecalciferol and parathyroid hormone in advanced chronic renal failure: effects of simultaneous protein and phosphorus restriction.

1986 • 82 citations

Evidence that serum calcium oxalate supersaturation is a consequence of oxalate retention in patients with chronic renal failure.

1986 • 79 citations

Effect of Dietary Protein Restriction on the Development of Renal Failure after Subtotal Nephrectomy in Rats

1983 • 79 citations

The risks and benefits of a low protein–essential amino acid–keto acid diet

1986 • 77 citations

Amelioration of experimental glomerulonephritis by dietary protein restriction

1983 • 75 citations

Restricted phosphorus and nitrogen intake to slow the progression of chronic renal failure: a controlled trial.

1983 • 68 citations

Effect of parathyroid hormone on phosphate reabsorption in rat distal convolution

1978 • 62 citations

Retardation of the progression of renal insufficiency in patients treated with low-protein diets.

1983 • 61 citations

Calcium metabolism in uremic nephrocalcinosis: Preventive effect of verapamil

1985 • 61 citations

Low-protein diet prevents glomerular damage in adriamycin-treated rats

1985 • 58 citations

Low-protein diet supplemented by keto acids in chronic renal failure: a prospective controlled study.

1983 • 57 citations

Precipitation of calcium phosphates from electrolyte solutions V. The influence of citrate ions

1979 • 57 citations

Calcium reabsorption in the thin loop of Henle

1974 • 54 citations

Effects of high and low protein diets on sheep renal function and metabolism

1973 • 53 citations

Protein restriction in chronic renal failure

1982 • 52 citations

Effect of Thyroparathyroidectomy and Parathyroidectomy on Renal Function and the Nephrotic Syndrome in Rat Nephrotoxic Serum Nephritis

1981 • 51 citations

Relationship between serum vitamin D metabolites and dietary intake of phosphate in patients with early renal failure.

1987 • 48 citations

Preventing the progression of human renal disease: Have rational therapeutic principles emerged?

1988 • 48 citations

Prolonged renal survival and stunting, with protein-deficient diets in experimental uremia. Reversal of these effects by addition of essential amino acids.

1981 • 47 citations

Suppression of secondary hyperparathyroidism in children with chronic renal failure by high dose phosphate binders: calcium carbonate versus aluminium hydroxide.

1985 • 47 citations

Early dietary protein and phosphorus restriction is effective in delaying progression of chronic renal failure.

1983 • 46 citations

Phosphate transport in superficial and deep nephrons in phosphate-loaded rats

1977 • 44 citations

Reversal of hyperparathyroidism in response to dietary phosphorus restriction in the uremic dog

1979 • 42 citations

Effects of parathyroid hormone on electrolyte transport in the hamster nephron

1979 • 41 citations

Effects of phosphate-induced hyperparathyroidism and parathyroidectomy on rat kidney calcium in vivo

1981 • 39 citations

Low protein and low phosphorus diet in patients with chronic renal failure: Influence on glucose tolerance and tissue insulin sensitivity

1987 • 38 citations

Effects of parathyroid hormone on cytosolic free calcium concentration in individual rabbit connecting tubules.

1989 • 38 citations

Observations on the kidney after phosphate loading in the rat.

1959 • 37 citations

Adaptation of deep and superficial nephrons to changes in dietary phosphate intake

1983 • 36 citations

Nephron heterogeneity of phosphate reabsorption

1978 • 35 citations

A micropuncture study of renal phosphate transport in rats with chronic renal failure and secondary hyperparathyroidism.

1978 • 35 citations

Beneficial Effect of Low Phosphorus Diet in Uraemic Rats: A Reappraisal

1982 • 34 citations

Renal Tubular Sites of Altered Calcium Transport in Phosphate-depleted Rats

1979 • 33 citations

Protein restriction in the conservative management of uremia

1978 • 33 citations

Decreased luminal membrane transport of phosphate in chronic renal failure

1982 • 28 citations

Prevention of phosphate-induced progression of uremia in rats by 3-phosphocitric acid

1982 • 27 citations

Effects of phosphate administration on tubular calcium transport.

1982 • 24 citations

Role of the control of phosphate in the progression of chronic renal failure.

1982 • 22 citations

Parathyroid hormone-independent adaptation of the renal handling of phosphate in response to renal mass reduction

1982 • 21 citations

Effects of a Low Phosphorus, Low Nitrogen Diet Supplemented with Essential Amino Acids and Ketoanalogues on Serum Triglycerides of Chronic Uremic Patients

1986 • 21 citations

The Effect of a High Protein Intake on Renal Function of Patients with Chronic Renal Insufficiency

1987 • 21 citations

Adverse effect of proteins on remnant kidney: dissociation from that of other nutrients.

1983 • 20 citations

Effects of somatostatin on phosphate transport: Evidence for the role of basal insulin

1983 • 20 citations

Role of renal prostaglandins in normal and nephrotic rats with diet-induced hyperfiltration.

1986 • 18 citations

Nephron heterogeneity of phosphate reabsorption: effect of parathyroid hormone

1984 • 16 citations

Functional profile of the isolated uremic nephron: Intrinsic adaptation of phosphate transport in the rabbit proximal tubule

1983 • 16 citations

Phosphate excretion in chronic renal failure: evidence for a mechanism other than circulating parathyroid hormone.

1977 • 15 citations

Improved dietary treatment with low protein and phosphorus restriction in uremic rats.

1983 • 13 citations

Early dietary protein restriction protects the failing kidney.

1985 • 12 citations

Effects of dietary phosphate restriction in children with chronic renal failure

1987 • 9 citations

Renal Phosphate Adaptation in Uraemic Dogs with a Remnant Kidney

1981 • 9 citations

Phosphate Handling by the Remnant Dog Kidney in the Presence and Absence of the Contralateral Normal Kidney

1980 • 7 citations

Fluid and Electrolytes

2005 • 5 citations