T cell autoreactivity against a 28 kD biliary protein (B1-p28) in primary biliary cirrhosis

Primary Biliary Cirrhosis

1987 • 1,981 citations

Symposium: Advances in Liver Pathology [Abridged]

1967 • 570 citations

ABERRANT EXPRESSION OF HLA-DR ANTIGENS ON BILEDUCT EPITHELIUM IN PRIMARY BILIARY CIRRHOSIS: RELEVANCE TO PATHOGENESIS

1984 • 496 citations

Protein disulfide isomerase. A multifunctional protein resident in the lumen of the endoplasmic reticulum.

1992 • 318 citations

PRIMARY BILIARY CIRRHOSIS IS A DRY GLAND SYNDROME WITH FEATURES OF CHRONIC GRAFT-VERSUS-HOST DISEASE

1980 • 233 citations

A simple new method for using antigens separated by polyacrylamide gel electrophoresis to stimulate lymphocytes in vitro after converting bands cut from Western blots into antigen-bearing particles

1987 • 231 citations

Primary Biliary Cirrhosis: A Model Autoimmune Disease

1983 • 220 citations

Primary biliary cirrhosis: Paradigm or paradox for autoimmunity

1991 • 204 citations

HLA DRw8 and complement C4 deficiency as risk factors in primary biliary cirrhosis

1991 • 140 citations

Evidence for the targeting by 2-oxo-dehydrogenase enzymes in the T cell response of primary biliary cirrhosis.

1991 • 139 citations

Primary biliary cirrhosis: Associations with class II major histocompatibility complex antigens

1987 • 133 citations

Leukocyte migration inhibition in response to biliary antigens in primary biliary cirrhosis, sclerosing cholangitis, and other chronic liver diseases

1979 • 121 citations

Ultrastructural immunocytochemical analysis of lymphocytes infiltrating bile duct epithelia in primary biliary cirrhosis

1986 • 118 citations

Susceptibility to primary biliary cirrhosis is associated with the HLA-DR8-DQB1*0402 haplotype

1992 • 115 citations

DNA typing of HLA class II genes; DRB1*0803 increases the susceptibility of Japanese to primary biliary cirrhosis

1994 • 109 citations

Analysis of hepatic T lymphocyte and immunoglobulin deposits in patients with primary biliary cirrhosis

1990 • 106 citations

Membrane dihydrolipoamide acetyltransferase (E2) on human biliary epithelial cells in primary biliary cirrhosis

1992 • 103 citations

T cell receptor gene rearrangements of T lymphocytes infiltrating the liver in chronic active hepatitis B and primary biliary cirrhosis (PBC): Oligoclonality of PBC‐derived T cell clones

1990 • 95 citations

Clonal analysis of human T lymphocytes infiltrating the liver in chronic active hepatitis B and primary biliary cirrhosis

1988 • 64 citations

Blood and liver-infiltrating lymphocytes in primary biliary cirrhosis: Increase in activated T and natural killer cells and recruitment of primed memory T cells

1991 • 61 citations

Cell-mediated Immune Response in Primary Biliary Cirrhosis to a Protein Fraction from Human Bile

1973 • 60 citations

Distribution of dihydrolipoamide acetyltransferase (E2) in the liver and portal lymph nodes of patients with primary biliary cirrhosis: An immunohistochemical study

1991 • 55 citations

An improved in vitro immunization procedure for the production of monoclonal antibodies against neural and other antigens

1984 • 47 citations

[DNA typing of HLA class II genes].

1990 • 40 citations

Primary biliary cirrhosis.

1987 • 37 citations

Autoantibody against dihydrolipoamide dehydrogenase, the E3 subunit of the 2-oxoacid dehydrogenase complexes: Significance for primary biliary cirrhosis

1991 • 36 citations

Clonal analysis of liver-derived T cells of patients with primary biliary cirrhosis.

1989 • 28 citations

Depletion of CD8+ cells exacerbates organ-specific autoimmune diseases induced by CD4+ T cells in semiallogeneic hosts with MHC class II disparity.

1990 • 26 citations

Differing epitope selection of experimentally-induced and natural antibodies to a disease-specific autoantigen, the E2 subunit of pyruvate dehydrogenase complex (PDC-E2)

1992 • 26 citations

Molecular aspects of the M2 autoantigens in primary biliary cirrhosis: What a difference a year makes

1989 • 18 citations

Cytotoxic activity of spleen‐derived T lymphocytes against autologous biliary epithelial cells in autopsy patients with primary biliary cirrhosis

1993 • 12 citations

Primary biliary cirrhosis

1985 • 11 citations

Autoreactivity against biliary tract antigens in primary biliary cirrhosis

1985 • 9 citations

Propagation and characterization of lymphocytes infiltratiti livers of patients with primary biliary cirrhosis and autoimmune hepatitis

1990 • 9 citations

A biliary protein identified by immunoblotting stimulates proliferation of peripheral blood T lymphocytes in primary biliary cirrhosis

1991 • 5 citations

The association of primary biliary cirrhosis with HLA DRw8 in Japan

1993 • 4 citations

The human pyruvate dehydrogenase complex: a polymorphic region of the lipoate acetyl transferase (E2) subunit gene

1991 • 4 citations

Cellular autoimmunity against bile derived autoantigen in patients with primary biliary cirrhosis.

1990 • 2 citations