Mutants in a Small Heat Shock Protein That Affect the Oligomeric State

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

SWISS‐MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modeling

1997 • 10,943 citations

Generic Assignments, Strain Histories and Properties of Pure Cultures of Cyanobacteria

1979 • 7,419 citations

How to measure and predict the molar absorption coefficient of a protein

1995 • 3,771 citations

[85] Construction of specific mutations in photosystem II photosynthetic reaction center by genetic engineering methods in Synechocystis 6803

1988 • 975 citations

Crystal structure of a small heat-shock protein

1998 • 876 citations

A small heat shock protein stably binds heat-denatured model substrates and can maintain a substrate in a folding-competent state

1997 • 772 citations

Binding of non-native protein to Hsp25 during heat shock creates a reservoir of folding intermediates for reactivation

1997 • 750 citations

Regulation of Hsp27 Oligomerization, Chaperone Function, and Protective Activity against Oxidative Stress/Tumor Necrosis Factor α by Phosphorylation

1999 • 716 citations

Crystal structure and assembly of a eukaryotic small heat shock protein.

2001 • 698 citations

Genealogy of the α-crystallin—small heat-shock protein superfamily

1998 • 480 citations

A Small Heat Shock Protein Cooperates with Heat Shock Protein 70 Systems to Reactivate a Heat-Denatured Protein

2000 • 454 citations

Hsp26: a temperature-regulated chaperone

1999 • 446 citations

Structure and function of the small heat shock protein/α-crystallin family of molecular chaperones

2001 • 428 citations

Mutation R120G in αB-crystallin, which is linked to a desmin-related myopathy, results in an irregular structure and defective chaperone-like function

1999 • 369 citations

Small heat shock proteins, ClpB and the DnaK system form a functional triade in reversing protein aggregation

2003 • 366 citations

The Small Heat-shock Protein IbpB from Escherichia coli Stabilizes Stress-denatured Proteins for Subsequent Refolding by a Multichaperone Network

1998 • 351 citations

HSP27 Multimerization Mediated by Phosphorylation-sensitive Intermolecular Interactions at the Amino Terminus

1999 • 324 citations

Structure and in Vitro Molecular Chaperone Activity of Cytosolic Small Heat Shock Proteins from Pea

1995 • 322 citations

sHsps and their role in the chaperone network

2002 • 288 citations

Subunit Exchange of αA-Crystallin

1997 • 286 citations

Structure and function of small heat shock/α-crystallin proteins: established concepts and emerging ideas

2000 • 254 citations

Structure-Function Studies on Small Heat Shock Protein Oligomeric Assembly and Interaction with Unfolded Polypeptides

1997 • 223 citations

Use of a scanning densitometer or an ELISA plate reader for measurement of nanogram amounts of protein in crude extracts from biological tissues

1988 • 202 citations

Molecular analysis of the flagellar switch protein FliM of Salmonella typhimurium

1992 • 185 citations

Changes in Oligomerization Are Essential for the Chaperone Activity of a Small Heat Shock Protein in Vivo and in Vitro

2002 • 172 citations

pJC20 and pJC40 - Two High-Copy-Number Vectors for T7 RNA Polymerase-Dependent Expression of Recombinant Genes in Escherichia coli

1994 • 162 citations

Chaperone-like Activity and Temperature-induced Structural Changes of α-Crystallin

1997 • 122 citations

Functional Elements in Molecular Chaperone α-Crystallin: Identification of Binding Sites in αB-Crystallin

1997 • 114 citations

Interactions between Small Heat Shock Protein Subunits and Substrate in Small Heat Shock Protein-Substrate Complexes

2004 • 110 citations

Monodisperse Hsp16.3 Nonamer Exhibits Dynamic Dissociation and Reassociation, with the Nonamer Dissociation Prerequisite for Chaperone-like Activity

2002 • 101 citations

A critical motif for oligomerization and chaperone activity of bacterial α‐heat shock proteins

2002 • 94 citations

On the mechanism of chaperone activity of the small heat-shock protein ofMethanococcus jannaschii

2003 • 72 citations

Structure and Energetics of an Allele-Specific Genetic Interaction between dnaJ and dnaK: Correlation of Nuclear Magnetic Resonance Chemical Shift Perturbations in the J-Domain of Hsp40/DnaJ with Binding Affinity for the ATPase Domain of Hsp70/DnaK

2003 • 52 citations

Compensatory Changes in GroEL/Gp31 Affinity as a Mechanism for Allele-specific Genetic Interaction

1999 • 32 citations

Multi-subunit assembly of the Pyrococcus furiosus small heat shock protein is essential for cellular protection at high temperature

2003 • 24 citations

[31] Determination of quaternary structure of an active enzyme using chemical cross-linking with glutaraldehyde

1988 • 22 citations

Thermally induced disintegration of the oligomeric structure of alphaB-crystallin mutant F28S is associated with diminished chaperone activity.

2003 • 17 citations