Effect of CCK and its antagonists on gastric emptying

Two brain cholecystokinin receptors: implications for behavioral actions

1986 • 719 citations

Development of a class of selective cholecystokinin type B receptor antagonists having potent anxiolytic activity.

1990 • 501 citations

A new potent and selective non-peptide gastrin antagonist and brain cholecystokinin receptor (CCK-B) ligand: L-365,260

1989 • 404 citations

Cholecystokinin suppresses food intake by inhibiting gastric emptying

1982 • 330 citations

A potent nonpeptide cholecystokinin antagonist selective for peripheral tissues isolated from Aspergillus alliaceus

1985 • 314 citations

Inhibition of Gastric Emptying is a Physiological Action of Cholecystokinin

1975 • 274 citations

Regulation of gastric emptying in humans by cholecystokinin.

1986 • 269 citations

Proglumide and benzotript: members of a different class of cholecystokinin receptor antagonists.

1981 • 231 citations

ROLE OF CHOLECYSTOKININ IN REGULATION OF GASTROINTESTINAL MOTOR FUNCTIONS

1989 • 229 citations

Evidence that Acetylcholine Released by Gastrin and Related Polypeptides Contributes to their Effect on Gastrointestinal Motility

1973 • 217 citations

Cholecystokinin Antagonists

1991 • 191 citations

Receptors on smooth muscle cells: characterization by contraction and specific antagonists

1982 • 181 citations

Role of cholecystokinin in the regulation of gastric emptying and pancreatic enzyme secretion in humans

1991 • 174 citations

Effects of a novel cholecystokinin (CCK) receptor antagonist, MK-329, on gallbladder contraction and gastric emptying in humans. Implications for the physiology of CCK.

1989 • 156 citations

Action of caerulein on gastric emptying of the conscious rat.

1980 • 141 citations

In vivo pharmacology of L-364,718, a new potent nonpeptide peripheral cholecystokinin antagonist.

1987 • 137 citations

Effects of cholecystokinin-octapeptide (CCK-8) on food intake and gastric emptying in man

1988 • 130 citations

Classification and function of CCK receptors

1987 • 121 citations

Cholecystokinin-58 is the major circulating form of cholecystokinin in canine blood.

1987 • 117 citations

Cholecystokinin and gastrin antagonists

1989 • 74 citations

Acetylcholine-releasing effect of gastrin and related polypeptides

1972 • 73 citations

Cholecystokinin antagonists

1989 • 73 citations

Action of the cholecystokinin antagonist L364,718 on gastric emptying in the rat

1988 • 72 citations

Cholecystokinin inhibits gastric acid secretion through type "A" cholecystokinin receptors and somatostatin in rats

1992 • 70 citations

Cholecystokinin is a physiological hormonal mediator of fat‐induced inhibition of gastric emptying in man

1988 • 62 citations

Distinct receptors for cholecystokinin and gastrin on muscle cells of stomach and gallbladder

1990 • 62 citations

Benzodiazepine analogues L365,260 and L364,718 as gastrin and pancreatic CCK receptor antagonists

1989 • 61 citations

Electrical and mechanical effects of molecular variants of CCK on antral smooth muscle.

1978 • 60 citations

Penetration of diazepam and the non-peptide CCK antagonist, L-364, 718, into rat brain

1987 • 60 citations

Detection of cholecystokinin-58 in human blood by inhibition of degradation

1987 • 59 citations

Characterization of gastrin receptors on guinea pig pancreatic acini

1987 • 57 citations

Evidence that the action of cholecystokinin octapeptide on the guinea pig ileum longitudinal muscle is mediated in part by substance P release from the myenteric plexus

1981 • 56 citations

Regional and cellular heterogeneity of cholecystokinin receptors mediating muscle contraction in the gut

1987 • 54 citations

The effect of the cholecystokinin receptor antagonist MK-329 on meal-stimulated pancreaticobiliary output in humans

1992 • 54 citations

What is Physiological?

1973 • 52 citations

Structure-antigastrin activity relationships of new (R)-4-benzamido-5-oxopentanoic acid derivatives

1992 • 50 citations

Cholecystokinin in the Inhibition of Gastric Secretion and Gastric Emptying in Humans

1990 • 48 citations

Roles of endogenous cholecystokinin in biliary, pancreatic and gastric function: studies with L-364,718, a specific cholecystokinin receptor antagonist.

1987 • 42 citations

Oral administration of loxiglumide (CCK antagonist) inhibits postprandial gallbladder contraction without affecting gastric emptying

1990 • 40 citations

The control of gastric emptying

1983 • 37 citations

Gastrointestinal Receptors and Drugs in Motility Disorders

1991 • 37 citations

Properties of receptors for gastrin and CCK on gastric smooth muscle cells

1989 • 34 citations

Inhibition of the action of cholecystokinin octapeptide on the guinea pig ileum myenteric plexus by dibutyryl cyclic guanosine monophosphate

1980 • 34 citations

Proglumide, a cholecystokinin antagonist, increases gastric emptying in rats

1987 • 31 citations

Effects of cholecystokinin and caerulein on gastric emptying

1982 • 31 citations

The Role of Local Cholinergic Pathways in the Motor Response to Cholecystokinin and Gastrin in Isolated Guinea-pig Fundus and Antrum

1977 • 31 citations

Clinical Efficacy and Prokinetic Effect of the CCK‐A Antagonist Loxiglumide in Nonulcer Dyspepsia

1994 • 31 citations

Functionally distinct receptors for cholecystokinin and gastrin on dispersed chief cells from guinea pig stomach

1988 • 31 citations

Intraventricular CCK inhibits food intake and gastric emptying in baboons

1989 • 28 citations

Effect of CCK antagonist L 364718 on meal-induced pancreatic secretion in rats

1990 • 27 citations

Characterization of antigastrin activity in vivo of CR 2194, a new R-4-benzamido-5-oxo-pentanoic acid derivative

1992 • 24 citations

Effect of metoclopramide, bethanechol and the cholecystokinin receptor antagonist, L-364,718, on gastric emptying in the rat

1988 • 21 citations

The Effect of Cholecystokinin on Human <i>Taenia col</i><i>i</i>

1977 • 21 citations

Cholecystokinin Antagonists in Gastroenterology

1991 • 21 citations

Perspectives of CCK antagonists in pancreatic research and clinical use

1991 • 20 citations

A model of gastric emptying in cats shows solid emptying is promoted by MK-329: a CCK antagonist.

1990 • 19 citations

The effects of cholecystokinin octapeptide on human isolated alimentary muscle

1990 • 19 citations

Cholecystokinin Antagonists

1986 • 18 citations

Low immunoreactivity of canine cholecystokinin-58

1990 • 17 citations

Involvement of endogenous opiates in regulation of gastric emptying of fat test meals in mice

1988 • 16 citations

Direct Effects of Cholecystokinin on Human Gastric Motility

1988 • 14 citations

Influence of enkephalinase inhibitors on gastric emptying in mice depends on the nature of the meal

1988 • 14 citations

Caerulein delays gastric emptying of solids in man.

1981 • 13 citations

Pharmacological Bases of the Medical Treatment of Gastroesophageal Reflux Disease

1988 • 13 citations

What is Physiological? Round 2

1974 • 11 citations

Receptor type for cholecystokinin on isolated intestinal muscle cells of the guinea pig

1990 • 10 citations

Cholecystokinin Antagonists and Motilides: Pharmacology and Potential in the Treatment of Gastroesophageal Reflux Disease and Other Digestive Motor Disorders

2015 • 10 citations

Peptides: Gastrointestinal Hormones

1982 • 7 citations

Gastrointestinal Drug Receptors

1983 • 7 citations

Influence of Stress on Gastric Emptying Depends on the Nature of Meals, Stressors, and Animal Species

1990 • 6 citations

Effect of JO 1754, A new CCKA antagonist on gastric emptying

1990 • 4 citations

Drug ekfects on gastric emptying in animal models depend on the nature of test meals used

1988 • 3 citations

Drug effects on gastric emptying in animal models depend on the nature of test meals used

1988 • 3 citations

Biological Actions of CCK in the Gastrointestinal Tract

1991 • 3 citations

Interaction of fedotozine (JO 1196) a new drug acting on gastrointestinal motility, with opioid receptors

1990 • 3 citations

Potential Methodologic Problems with in Vivo Immunoneutralization of Pancreatic Polypeptide

1987 • 2 citations

Antinociceptive and gastrointestinal transit effects of cholecystokinin (CCK-8) and related analogs of CCK-8 in the mouse.

1991 • 2 citations

Effect of devazepide on caerulein and camostate induced delay of gastric emptying in the rat

1992 • 1 citations

Deleted Work

1955 • 0 citations