Response to neo-adjuvant chemotherapy in women with BRCA1-positive breast cancers

Effect of preoperative chemotherapy on the outcome of women with operable breast cancer.

1998 • 2,115 citations

Breast Cancer Molecular Subtypes Respond Differently to Preoperative Chemotherapy

2005 • 1,833 citations

Germline BRCA1 Mutations and a Basal Epithelial Phenotype in Breast Cancer

2003 • 938 citations

Multifactorial Analysis of Differences Between Sporadic Breast Cancers and Cancers Involving BRCA1 and BRCA2 Mutations

1998 • 695 citations

The Breast Cancer Susceptibility Gene BRCA1 Is Required for Subnuclear Assembly of Rad51 and Survival following Treatment with the DNA Cross-linking Agent Cisplatin

2000 • 565 citations

The Role of BRCA1 in the Cellular Response to Chemotherapy

2004 • 426 citations

BRCA1 functions as a differential modulator of chemotherapy-induced apoptosis.

2003 • 383 citations

Homology-directed dna repair, mitomycin-c resistance, and chromosome stability is restored with correction of a Brca1 mutation.

2001 • 379 citations

The Prognostic Implication of the Basal-Like (Cyclin Ehigh/p27low/p53+/Glomeruloid-Microvascular-Proliferation+) Phenotype of BRCA1 -Related Breast Cancer

2004 • 367 citations

BRCA1 expression modulates chemosensitivity of BRCA1-defective HCC1937 human breast cancer cells

2003 • 354 citations

Tumour biological features of BRCA1-induced breast and ovarian cancer

1997 • 346 citations

Founder Mutations in the BRCA1 Gene in Polish Families with Breast-Ovarian Cancer

2000 • 259 citations

Inhibition of BRCA1 leads to increased chemoresistance to microtubule-interfering agents, an effect that involves the JNK pathway

2001 • 188 citations

A high proportion of founder BRCA1 mutations in Polish breast cancer families

2004 • 186 citations

Targeting the DNA repair defect of BRCA tumours

2005 • 159 citations

BRCA1 Downregulation Leads to Premature Inactivation of Spindle Checkpoint and Confers Paclitaxel Resistance

2006 • 155 citations

The effect of loss of Brca1 on the sensitivity to anticancer agents in p53-deficient cells

2003 • 113 citations

Brca2 hereditary breast cancer pathophenotype

1997 • 78 citations

Role of BRCA1 in cellular resistance to paclitaxel and ionizing radiation in an ovarian cancer cell line carrying a defective BRCA1

2003 • 74 citations

BRCA1-positive breast cancers in young women from Poland

2006 • 46 citations